Accelerate, protect, and restore your mouse lines with JAX's comprehensive assisted reproductive and rescue services. Whether you need to cleanse a strain of pathogens, maintain complex genotypes, or recover a colony at risk of extinction, JAX delivers high-health-status animals supported by world-leading reproductive science.
Quickly restore your mouse line to high health status. JAX performs IVF sperm rederivation and embryo rederivation to remove viruses, bacteria, and parasites and deliver SOPF/SPF offspring with full health reports, typically in ~12-15 weeks. These services are used to import external lines, clear quarantine requirements, recover a strain after pathogen detection, or standardize health status across sites for reproducible studies.
Our Standard IVF Rederivation Service (sperm rederivation) requires only two males from your colony. Should you need additional animals, this service can be easily scaled to produce large numbers of offspring.
Our Custom Rederivation Service can receive both males and females from your colony, but if you are not in the position to provide the number of mice in the age ranges required for rederivation, we can provide breeding services to expand colonies and produce the mice needed. Upon request, genotyping services can be added for an additional fee.
| Standard IVF Rederivation | Speed Congenic | |
|---|---|---|
| Ideal For |
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| Requirements | 2+ males of the same genotype 8-16 weeks of age Females provided by JAX | 2+ male mice and 8-12 female mice from your colony |
| Deliverable | At least 8 pups. Health report is included. | At least 2 pair of mice. Health report included. |
| Estimated Timeline | 12-15 weeks | 12-15 weeks |
Save endangered mouse lines, restore breeding and protect irreplaceable genetics. JAX Strain Rescue is a focused, rapid-response service for colonies threatened by age, breeding cessation, or poor health. We apply our nearly 100 years of experience and advanced assisted reproductive technologies to recover viable animals and secure your model's future.
Our team has rescued over 150 mouse strains from extinction due to breeding cessation or health issues. If your mouse colonies have ceased reproducing or are threatened by health or other issues, JAX may be able to help.
Recover your failing strain with JAX
| Service | Strain Rescue |
|---|---|
| Ideal For | Designed to rescue small colonies threatened by age, breeding cessation or poor health |
| Requirements | 2+ male carrier mice, 9-18 months old from your colony |
| Deliverable | All recovered pups, recovered at a SOPF status |
| Estimated Timeline | 12-15 weeks |
Genetic drift occurs in any independent mouse breeding colony and has the potential to negatively affect experimental reproducibility and scientific conclusions. Spontaneous mutations caused by genetic drift may go unrecognized for years, until the specific research questions that depend on such mutations happen to be addressed.
