The Jackson Laboratory

Colony Expansion Services

Accelerate your research timelines with JAX Expansion Services. Whether you need large, synchronized cohorts for in vivo studies or fast, precision-driven genetic transfer, JAX provides the speed, health quality, and scientific rigor required to quickly scale up your colony and keep your programs on schedule.

Our expert colony management, world leading genetic expertise, and highest ethical standards deliver high-health-status, genetically reliable, and experiment-ready animals faster than traditional methods.

Partner with JAX to shorten mouse colony development and genetic background refinement,

  • Compress breeding timelines by weeks to years, depending on your application (~50% faster than traditional breeding)
  • Reduce experimental variability with age-matched, controlled cohorts
  • Ensure reproducibility through high-health, genetically-verified animals

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The Jackson Laboratory - Colony Expansion Services

IVF Speed Expansion

IVF Expansion is one of the fastest ways to bypass the bottlenecks of traditional breeding. This service is used for large age-matched cohorts, rapid colony recovery after breeding challenges, tight developmental stage matching, or fast expansion of rare or low-fertility lines.

Using in vitro fertilization and high-efficiency embryo transfer, this service can produce 50+ synchronized offspring from as few as two male mice in as little as 3 months. This approach saves months compared to natural breeding, providing study-ready animals without compromising genetic quality or health status.

JAX IVF Expansion service delivers:

  • Rapid colony buildup: Cohorts ready in ~45 days
  • High consistency: Offspring delivered within a 2-3 day birth window—ideal for age-dependent studies
  • Build large colonies from just a few males: IVF produces high-volume offspring quickly without needing a large male breeding pool
  • High-health-status: SOPF-grade surrogate dams ensure clean, reliable starting colonies
  • Ideal for hard-to-breed strains: A great tool to overcome fertility, lifespan, or breeding-window challenges

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ServiceIVF Expansion
Ideal ForQuickly producing large quantities of same-age, SOPF mice on common genetic backgrounds
Requirements2 males 10-16 weeks of age. Females provided by JAX
DeliverableSOPF Mice, quantity depends on your research needs.
Estimated TimelineDependent on size of colony required, but faster than traditional breeding approaches.

JAX Speed Congenic Service

JAX Speed Congenic Service accelerates the process of transferring a mutation onto a specific inbred background and reduces timelines by 50%. This service is used for rapid transfer of targeted alleles to preferred backgrounds, eliminating unwanted genetic drift or variability, and increasing reproducibility across multi-site or long-term programs.

Conventional backcrossing requires ~10 generations and 2-3 years. With marker assisted breeding, JAX can deliver genetically well-defined congenic mice in ~18 months. This service combines SNP-based selection, high health status breeding, and hands-on project management to ensure genetic accuracy and scientific rigor.

Partner with JAX To Achieve Congenic Precision in Half the Time

  • 50% faster timeline: Reduce congenic generation from >3 years to ~18 months
  • High genetic precision: Achieve >99% desired background with marker assisted selection
  • Reliable inbred integrity: Fully managed backcrossing and genotyping
  • Study-ready delivery: High health status animals prepared for immediate expansion or experimental use

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ServiceSpeed Congenic
Ideal ForIVF Expansion with genotyping included to backcross your strain to a common inbred background, such as B6.
RequirementsFor external strains: Minimum of 2x Male HOM/HET mice (HOM preferred), 8-16 weeks of age
DeliverableCongenic mice (>99%) recovered 50% faster than traditional breeding and at at SOPF health status
Estimated Timeline15-18 months

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