Researchers are able to do many things today that were impossible five, three, even one year ago. Some of the new options are...
The genome editing tool, Casilio, can be used to efficiently remove methyl groups from DNA and activate expression of methylation-silenced...
C57BL/6—aka Black 6—is the most widely used mouse strain in research. Its reference genome was published in 2003 and has...
Two new mouse models created to study neurological developments in Snyder-Robinson Syndrome to advance global understanding of this rare...
Antibody stability and half-life prediction in humans require appropriate in vivo experimental models. JAX Therapeutic Antibody Evaluation...
Lead Scientist responsible for the development and validation of Mouse models associated with Clinically associated Rare and...
Learn how JAX designates mouse genotypes, and what “+” means in the context of inbred, mutant or transgenic strains.
Learn how the original BALB/c strain separated into two major substrains (BALB/cJ and BALB/cByJ) and how to decide which one...
B6 and B6N substrains differ genetically as a result of accumulated spontaneous mutations. Learn why it is important not to use different...
Learn about the evolution of genetic targeting techniques from ZNFs and TALENs to today’s CRISPR/Cas systems that allow...
The Animal Health Program at JAX ensures the health of our mouse colonies by preventing the entry of pathogens and minimizing opportunities...
Learn about the barrier facilities maintained at The Jackson Laboratory and the husbandry restrictions that apply to each...
The definitive resource for anyone working with laboratory mice, this is the 6th edition of The Jackson Laboratory Handbook on Genetically...
The definitive resource for anyone working with laboratory mice, this is the 6th edition of The Jackson Laboratory Handbook on Genetically...
Learn the highlights of mouse strain nomenclature with this poster.
A visual guide to the genes influencing coat color.