Animal Health Program
The Jackson Laboratory is committed to setting quality standards in animal care and ensuring that these standards are maintained throughout all of our mouse colonies.
This intensive workshop is for those wishing to obtain practical hands-on training in mouse surgical techniques. In addition to surgical...
Recently developed outbred mouse populations, such as the diversity outbred (DO) mice at The Jackson Laboratory (JAX), have created...
Learn about breeding Cre lox mice to turn on or off transgenes and using Cre reporter strains.
The impact of Dr. Snell’s work laid the foundation for understanding how transplantation could be successful both in experimental animals...
B6 and B6N substrains differ genetically as a result of accumulated spontaneous mutations. Learn why it is important not to use different...
Learn about the barrier facilities maintained at The Jackson Laboratory and the husbandry restrictions that apply to each...
The Jackson Laboratory diagnostic laboratory routinely monitors animal health status using statistically valid sampling...
Learn how the original BALB/c strain separated into two major substrains (BALB/cJ and BALB/cByJ) and how to decide which one...
Learn about the evolution of genetic targeting techniques from ZNFs and TALENs to today’s CRISPR/Cas systems that allow...
Learn how JAX designates mouse genotypes, and what “+” means in the context of inbred, mutant or transgenic strains.
Learn how in mouse models the gut microbiota can be selected by the host to enhance its tolerance to systemic infection.
Many mouse strains expressing Cre have unexpected phenotypes that may complicate the interpretation of your experiments. Here we dispel...
Learn how a neat reporter system is a powerful tool to track host-pathogen cell interactions during infection, clearance and phagocytosis...
Learn how a new method renders whole organs optically transparent to construct 3D maps to better understand organs in both normal and...
Learn how with the CRISPR/Cas system, you can generate genetically engineered mice within weeks, instead of years.
The Cre/lox system enables sophisticated control over the timing and location of gene expression. Learn the details about Cre-lox that too...
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