In this series, we compare and contrast the top mouse models for metabolic diseases as well as discuss how these models recapitulate different phenotypes, and how diet and the environment impacts disease progression. During these webinars, we discuss using popular models to understand the basis of obesity, diabetes, and cardiovascular diseases, and their application as preclinical models to develop superior therapeutics for these diseases.
This series provides information essentials for successfully using mouse models in biomedical research. During these webinars, investigators from all research areas as well as veterinary and animal care professionals will master the fundamentals of deciphering mouse nomenclature, best practices to optimize the management of mouse colonies, experimental design using power analysis, optimizing challenging breeding schemes, and understanding key differences among B6 substrains.
Cancer is a heterogeneous collection of diseases characterized by uncontrolled cell growth and spread to distant organs. In this series, we discuss mouse models and techniques used to answer basic and preclinical research questions about cancer initiation, progression, and therapeutic interventions. We will cover how to care for immunodeficient strains, proper model selection and generation, novel modeling strategies which more accurately predict human cancer response and considerations for designing successful animal experiments. Join us in the War on Cancer.
The immune system is involved in a wide array of human diseases with roles in allergy, inflammation, infection, neurodegeneration, Type 1 diabetes, and cancer. In this series, we provide considerations for selecting appropriate models, best practices for immunodeficient mouse care, methods to generate mouse models with humanized immune systems, and approaches for using these humanized mouse models in human infectious disease and cancer research.
Mouse models are the platform of choice for modeling human diseases because of their genetic similarities with humans, their short reproductive cycle, and the relative ease of manipulating the mouse genome. In this webinar series, learn methods to investigate and manipulate gene activity and advance our understanding of disease using the Cre-lox system or CRISPR/Cas targeting strategies. Additionally, discover how human cancers and humanized immune systems can be studied effectively in mice. These simple yet sophisticated approaches can generate a vast array of mouse models to advance your specific discovery research projects in the areas of cancer, neurobiology, immunity, and more.