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Platforms for Autoimmune Disease Drug Discovery: Improve Translational RelevanceMay 6, 2021, 1:00 PM USA Eastern Time Would you like to improve the translational relevance of your preclinical autoimmune disease discovery research? During this presentation, we will discuss the various preclinical platforms available, including novel humanized mouse models that are being used to develop treatments for diseases such as systemic lupus erythematosus, psoriasis, and type 1 diabetes. |
Improved Disease Modeling of Diverse Patient Populations with Diversity Outbred MiceMay 27, 2021, 1:00 PM USA Eastern Time Do you need a research platform that more accurately reflects disease progression and treatment in genetically diverse patient populations? Unlike genetically uniform inbred mice, The Jackson Laboratory’s diversity outbred (J:DO) mice have high genetic and phenotypic diversity resulting from intercrossing eight founder strains. During this presentation, we will discuss how J:DO mice promote translationally-relevant research in pharmacology, toxicology, and biomedical research. |
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I study the implication of myeloid cells, particularly antigen-presenting cells (APCs), in antiviral immune response.
International database resource for the laboratory mouse, providing integrated genetic, genomic, and biological data.
New preclinical data reported in the journal Science Translational Medicine (Burak et al., 2015) demonstrates that a monoclonal antibody to...
“Optopatch” mice allow both optogenetic stimulation and simultaneous optical recording of electrical outputs in the same neuron. They are...
Learn about the pros and cons of using Apoe or Ldlr knockout mice for atherosclerosis research.
Computational Oncology studies that integrate clinical, genomic, and imaging data to explore the dynamics of tumor heterogeneity and...
Learn how mice lacking OPN are protected against the development of diet-induced obesity (DIO) and hepatic steatosis.
The closer we are to accurately modeling genetic diseases in the mouse, the closer we are to discovering cures in the...
It’s the New Year. Did you resolve to lose weight (again)? Using optogenetic approaches and behavioral assays in mice, neuroscientists at...
Neuroscience is still a young science. Optogenetics provides an intriguing way to explore what’s going on inside our brains.
Learn about a method that combines optogenetic and multi-electrode systems to provide spatiotemporal modulation of and simultaneous...
This course includes daily lectures in the mornings and evenings as well as afternoon mini-symposia, workshops, tutorials, demonstrations...
This course includes daily lectures in the mornings and evenings as well as afternoon mini-symposia, workshops, tutorials, demonstrations...
This course includes daily lectures in the mornings and evenings as well as afternoon mini-symposia, workshops, tutorials, demonstrations...
This live, virtual course is a modern survey of heredity, disease, genetics in experimental animals and humans, and...
Learn how seven immunodeficient mouse models helped figure out which cell types mediate the autoimmune destruction of insulin-producing...
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