Cancer
In this series, we discuss mouse models and techniques used to answer basic and preclinical research questions about cancer initiation, progression, and therapeutic interventions.
Register for our complimentary, interactive live webinars!
De-Risk Therapeutic Antibody Drug Development Using Humanized FcRn MiceMay 28, 2020, 1:00 PM USA Eastern Time Do you need reliable pharmacokinetic (PK) data to evaluate human immunoglobulin or albumin-based therapeutic drug candidates? The humanized FcRn (Hu-FcRn) mouse model enables you to obtain clinically-relevant PK data related to drug half-life. This critically important PK data helps optimize the design of preclinical efficacy studies and to de-risk lead selection. |
Comparing Immunodeficient Mice for Cancer, Immunity, and Transplant ResearchJune 4, 2020, 1:00 PM USA Eastern Time Mouse strains with varying degrees of immunodeficiency are powerful tools for modeling human disease. In this webinar, we will discuss the most widely-used immunodeficient mouse models and important considerations for selecting the most appropriate model. |
Having trouble connecting to a live webinar? Click here for assistance.
In this series, we discuss mouse models and techniques used to answer basic and preclinical research questions about cancer initiation, progression, and therapeutic interventions.
In this series, we provide considerations for selecting appropriate models, best practices for immunodeficient mouse care, methods to generate mouse models with humanized immune systems, and approaches for using these humanized mouse models in human infectious disease and cancer research.
In this webinar series, learn methods to investigate and manipulate gene activity and advance our understanding of disease using the Cre-lox system or CRISPR/Cas targeting strategies.
The Jackson Laboratory maintains the world’s largest collection of mouse models for neurobiology research studies. In this webinar series, we discuss various mouse models of neurological diseases and their use in preclinical and basic biomedical research.
This series provides information essentials for successfully using mouse models in biomedical research.
In this series, we compare and contrast the top mouse models for metabolic diseases as well as discuss how these models recapitulate different phenotypes, and how diet and the environment impact disease progression.
International database resource for the laboratory mouse, providing integrated genetic, genomic, and biological data.
The traditional approach to genetic testing for those of Ashkenazi Jewish ancestry is under debate, with some experts calling for testing...
New preclinical data reported in the journal Science Translational Medicine (Burak et al., 2015) demonstrates that a monoclonal antibody to...
“Optopatch” mice allow both optogenetic stimulation and simultaneous optical recording of electrical outputs in the same neuron. They are...
3D-genome technologies, Structural Variants, Cancer biology
RNA Biology- RNA modifications and Diseases
This is a four-day, professional development course geared towards senior graduate students and postdoctoral fellows, which will help you...
Learn about the pros and cons of using Apoe or Ldlr knockout mice for atherosclerosis research.
RNA splicing and cancer
PDX tumor models retain much of the biological diversity and heterogeneity of the original patient tumor. Advances in the development of...
Learn how mice lacking OPN are protected against the development of diet-induced obesity (DIO) and hepatic steatosis.
The closer we are to accurately modeling genetic diseases in the mouse, the closer we are to discovering cures in the...
It’s the New Year. Did you resolve to lose weight (again)? Using optogenetic approaches and behavioral assays in mice, neuroscientists at...
Neuroscience is still a young science. Optogenetics provides an intriguing way to explore what’s going on inside our brains.
This course includes daily lectures in the mornings and evenings as well as afternoon mini-symposia, workshops, tutorials, demonstrations...