Cancer
In this series, we discuss mouse models and techniques used to answer basic and preclinical research questions about cancer initiation, progression, and therapeutic interventions.
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Genetic Drift: What it is and How to Minimize Its Impact on Your ResearchOctober 18, 2018, 1:00 PM ET, 5:00 PM GMT The phenotypes of genetically modified mouse strains depend on the genetic mutation and background. Genetic background is subject to genetic drift that may result in phenotypic drift over time. |
Neuromuscular Platforms for Drug DiscoveryOctober 27, 2018, 1:00 PM ET, 5:00 PM GMT Designing and validating mouse models for the study of neurological diseases presents a unique set of challenges. Proper model selection and rigorous study design and execution are vital in ensuring translational validity. In this presentation, we discuss considerations for selecting models, readouts, and study designs to evaluate the efficacy of potential therapeutics for neuromuscular diseases. |
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International database resource for the laboratory mouse, providing integrated genetic, genomic, and biological data.
This is a NEW one-of-a-kind workshop on mouse stereotaxic surgery being held in Paris, France. Participants attending this course will...
New preclinical data reported in the journal Science Translational Medicine (Burak et al., 2015) demonstrates that a monoclonal antibody to...
It’s the New Year. Did you resolve to lose weight (again)? Using optogenetic approaches and behavioral assays in mice, neuroscientists at...
“Optopatch” mice allow both optogenetic stimulation and simultaneous optical recording of electrical outputs in the same neuron. They are...
Learn about a method that combines optogenetic and multi-electrode systems to provide spatiotemporal modulation of and simultaneous...
Learn about the effects of feeding a high fat diet to NON/ShiLtJ males, a new mouse model for diet-induced obesity (DIO) and...
Learn about the pros and cons of using Apoe or Ldlr knockout mice for atherosclerosis research.
Learn how mice lacking OPN are protected against the development of diet-induced obesity (DIO) and hepatic steatosis.
This workshop provides training in the use of genetically defined laboratory mice as tools for asking questions about gene function and the...
Neuroscience is still a young science. Optogenetics provides an intriguing way to explore what’s going on inside our brains.
This course includes daily lectures in the mornings and evenings as well as afternoon mini-symposia, workshops, tutorials, demonstrations...
This course includes daily lectures in the mornings and evenings as well as afternoon mini-symposia, workshops, tutorials, demonstrations...
Learn how seven immunodeficient mouse models helped figure out which cell types mediate the autoimmune destruction of insulin-producing...
Aiming to understand the aging process from a microbiome prospective, looking for interventions on aging related chronic low-grade...
This JAX course will focus on the use of the innovative tools and methods, specifically in the laboratory mouse, for answering questions of...
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