About
Functional Genomics Essentials Course
What comes after genome-wide association studies or the identification of a potentially pathogenic variant within your study population? Delve into our Functional Genomics Webinar Series to explore how cells, tissues, organs, and biological systems collaboratively generate diverse phenotypes. The objective of this course is to furnish participants with foundational knowledge in functional genomics, as well as freely available analytical platforms, enabling them to comprehend disease mechanisms, validate gene-disease associations, and cultivate diagnostics and therapeutics for precision medicine, ultimately benefiting global health.
After conducting genome-wide association studies or identifying potentially pathogenic variants within your study population, the next step involves a deep dive into our Functional Genomics Webinar Series. This series delves into how cells, tissues, organs, and biological systems work together to contribute to diverse phenotypes. The primary goal of this course is to equip participants with fundamental insights into functional genomics and introduce freely available analytical platforms. This knowledge empowers participants to understand disease mechanisms, validate gene-disease associations, and develop diagnostics and therapeutics for precision medicine, contributing to the improvement of global health. Join us on this educational journey to unravel the intricacies of functional genetics and genomics.
The "Introduction to Functional Genetics" course, organized collaboratively by AfSHG-YIF, ESHG-Y, and JAX Labs, is a comprehensive exploration of functional genomics. Delivered through four sessions spanning April 29-30 and May 6-7, this online course aims to provide participants with a nuanced understanding of functional genomics tools, databases, and practical applications. Experts from JAX, AfSHG, and ESHG will guide participants through essential topics, including in silico tools, genome editing, and Mouse Genomics Informatics (MGI).
About
Participants will be introduced to functional genomics experiments and analyses and to select tools and resources that can be applied to their research. Course topics include:
- Introduction to functional genomics and its significance
- Overview of select functional genomics tools and their applications
- In silico tools for functional genomics
- Models for in vivo and in vitro functional genomics
- Introduction to specific online databases/tools
- Designing functional genetics models (cells/animals) using genome editing resources (Knockout, knock-in, silencing, site-directed mutagenesis, and conditional mutagenesis)
- Mouse Genomics Informatics (MGI)
- Exploring genes, variants, genotypes, strains, ontologies, and disease terminologies.
- Utilizing MGI to study diseases and their genotype-to-phenotype correlations.
- Analysis and application utilizing the MGI expression database.
- Utilizing the Human-Mouse Disease Database.
- Resources for translating genetic variants between human and mouse models, as well as other model systems.
Join us in this exciting journey to delve into the world of functional genomics! Expand your knowledge, interact with experts, and gain practical insights that can enhance your understanding of this rapidly evolving field.
Eligible participants:
This virtual course is tailored for African and European graduate students, post-doctoral fellows, and early career scientists, including young faculty members of the AfSHG, engaged in genome-wide association studies, genetics/genomic research, population genetics, and related fields. Participants affiliated with the Young Investigators of the African Society of Human Genetics and the European Society of Human Genetics-Young will be prioritized
This virtual course is specifically designed for graduate students, post-doctoral fellows, and early career scientists from Africa and Europe who are actively involved in genome-wide association studies, genomic research, population genetics, and related fields. Priority consideration will be given to participants associated with the Young Investigators of the African Society of Human Genetics and the European Society of Human Genetics-Young.