The Jackson Laboratory

2026 Computational Sciences Publications

2026 Publications:

  1. Yang T, Huhe H, Williams SP, Kaur S, Ay YA, Davis-Gilbert ZW, Cary GA, Paisie C, Butler RR, 3rd, Wiley J, Betarbet R, Fu H, Duong D, Seyfried NT, Leal K, Carter GW, Edwards A, Levey AI, Capener JL, Drewry DH, Hossain MA, Oh HJ, Axtman AD, Sukoff Rizzo SJ, Longo FM, The Emory-Sage-SGC-JAX TREAT-AD Center. PAK1 inhibitor NVS-PAK1-1 preserves dendritic spines in amyloid/tau exposed neurons and 5xFAD mice. Alzheimers Dement. 2025;21(12):e71033. PMID: 41451871; PMCID: PMC12741935. https://libkey.io/libraries/3075/41451871

  2. Sabnis GS, Hession L, Mahoney JM, Mobley A, Santos M, Geuther B, Kumar V. Visual detection of seizures in mice using supervised machine learning. Cell Rep Methods. 2025;5(12):101242. PMID: 41308647. https://libkey.io/libraries/3075/41308647

  3. Ordaz T, Sundaramurthi JC, Arterbery AS, Bagley AM, Gargano MA, Bauer JP, Danis D, Giampietro P, Raney E, Rekerle L, Shingle M, Davids JR, Robinson PN. An ITPR1 Variant in the IP3-ITPR1 Binding Pocket Associated With a Clinical Phenotype of Athetoid Cerebral Palsy. Am J Med Genet A. 2026;200(2):459-67. PMID: 40968496. https://libkey.io/libraries/3075/40968496

  4. Cary GA, Li Q, Wiley JC, Paisie CA, Du Y, Zoeller EL, Duong D, Fu H, Seyfried NT, Levey AI, Betarbet R, Carter GW, for The Emory-Sage-SGC-JAX TREAT-AD Center. Integrated phenotypic and proteomic screening identifies top-tier Alzheimer's disease therapeutic targets. Alzheimers Dement. 2025;21(12):e71008. PMID: 41388808; PMCID: PMC12701361. https://libkey.io/libraries/3075/41388808

  5. Arnuk A, Han C, Lawal AE, Wang B, Karma S, Zhang Z, Yassouf MY, Rajendran SH, Chandok H, Eller ML, Sajedi S, McKenna M, Herman E, Hagen L, Nadorp B, Mo Z, Orellana H, Tsirigos A, Miura P, Abbas HA, Aifantis I, Wang E. Epigenetic reactivation of the tumor suppressor ZBTB7A by KDM4 inhibition in human acute myeloid leukemia. Sci Transl Med. 2026;18(838):eady2936. PMID: 41739902. https://libkey.io/libraries/3075/41739902

  6. Lindsay H, Du Y, Qi L, Zhang H, Zhao S, Braun FK, Kogiso M, Stephan C, Alton G, Stein G, Beaton G, Kesari S, Neuhauser S, Stearns T, Chuang J, Jocoy EL, Bult CJ, Teicher B, Smith MA, Li XN. Targeting Pediatric Glioblastomas by Combining OLIG2 Inhibitor CT-179 with Fractionated Radiation in a Panel of Patient-Derived Orthotopic Xenograft Mouse Models. Int J Mol Sci. 2026;27(3). PMID: 41683962; PMCID: PMC12898090. https://libkey.io/libraries/3075/41683962

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