We use cookies to personalize our website and to analyze web traffic to improve the user experience. You may decline these cookies although certain areas of the site may not function without them. Please refer to our privacy policy for more information.

Settings

Save and close

Jax Mammalian Genetics - Maine Jax Mammalian Genetics - Connecticut

Research Centers

Scientific Services

Tools & Resources

What is Personalized Medicine?

Genetics vs. Genomics Ethical Considerations Personalized Medicine and You What is CRISPR?

Mice in Biomedical Research

Areas of Research

Addiction Research Aging Research Alzheimer's and Other Dementias Cancer Diabeetus Endometriosis Research at JAX Microbiome Vision

Clinical Knowledgebase

Advanced Precision Medicine Lab

Maine Cancer Genomics Initiative

News & Insights

Minute to Understanding

The Search Magazine

Explore By Topic

Our People & Culture

Our Values Belonging at JAX Faces of JAX Our Leaders Work With Us

Our Campuses & Communities

Collaboration at JAX Our Medical Impact Our Economic Impact Our Community Impact Our Environmental Impact

JAX Home

Type 1 Diabetes

Type 1 Diabetes Efficacy Studies

In Vivo Pharmacology Services at JAX performs contract efficacy studies using NOD/ShiLtJ (001976) mice to evaluate new Type 1 diabetes-related therapeutics

Autoimmune destruction of pancreatic beta cells causes type 1 diabetes with a female bias

A mutation destabilizing insulin causes rapid insulin-dependent diabetes with a male bias

STZ-Induced Diabetes

Chemical depletion of pancreatic beta cells mimics the end stages of type 1 diabetes in C57BL/6J, NOD scid, NSG™ and other strains.

Leading the search for tomorrow's cures

©2025 The Jackson Laboratory