Autoimmune and
Inflammatory Diseases

The Jackson Laboratory has developed and validated numerous autoimmune in vivo models to interrogate therapeutic candidates in a relevant and translational manner. These platforms and readouts can help you make informed decisions about which candidates to move forward towards IND.

JMCRS - C22 - SBTA Autoimmune

Lupus Models

Established and emerging models are available to understand the origins and treatment of the most common form of lupus, systemic lupus erythematosus (SLE)

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Type 1 Diabetes Models

Pancreatic dysfunction underlies type 1 diabetes in mice including the commonly used autoimmune NOD/ShiLtJ model

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Inflammatory Bowel
Disease Models

Aberrant immune responses contribute to human inflammatory bowel disease as well as the mouse strains used to study colitis, Crohn’s disease, and other conditions

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