Autoimmune and
Inflammatory Diseases

The Jackson Laboratory has developed and validated numerous autoimmune in vivo models to interrogate therapeutic candidates in a relevant and translational manner. These platforms and readouts can help you make informed decisions about which candidates to move forward towards IND.

Lupus Models

Established and emerging models are available to understand the origins and treatment of the most common form of lupus, systemic lupus erythematosus (SLE)

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Type 1 Diabetes Models

Pancreatic dysfunction underlies type 1 diabetes in mice including the commonly used autoimmune NOD/ShiLtJ model

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Inflammatory Bowel
Disease Models

Aberrant immune responses contribute to human inflammatory bowel disease as well as the mouse strains used to study colitis, Crohn’s disease, and other conditions

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