Characterized Cre strains for craniofacial research
We are characterizing cre strains useful for craniofacial research as part of a related resource, the JAX Cre Repository. a centralized, comprehensive set of well-characterized Cre Driver lines and related information resources.
Strains listed below have undergone in-depth characterization in our group, following the Cre Repository staining protocols. Strains are listed alphabetically by promoter.
You can also visit creportal to search for Cre-expressing strains by promoter or site of activity, view detailed characterization of Cre activity including images, and get links to strains available in repositories.
|
Stock number(links to data sheet) |
Strain name |
Promoter (species) |
Expected site of expression |
Expression data thumbnail |
|---|---|---|---|---|
|
Krt17, keratin 17 (mouse) |
Cre recombinase expression is driven by the endogenous keratin 17 (Krt17) promoter/enhancer elements |
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Osr2, odd-skipped related 2 (Drosophila), mouse, laboratory |
Cre recombinase activity is reported in developing palate and urogenital tract |
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Trp63, transformation related protein 63 (mouse) |
Cre recombinase expression is driven by Trp63promoter/enhancer elements |
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Prrx1, paired related homeobox 1 (rat) |
Cre recombinase activity is expected in early limb bud mesenchyme and in a subset of craniofacial mesenchyme, along with limited female germline expression |
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Tgfb3, transforming growth factor, beta 3 (mouse) |
Cre recombinase activity is expected in the heart, pharyngeal arches, otic vesicle, mid brain, limb buds, midline palatal epithelium, and whisker follicles during embryo and fetus development |
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Wnt1, wingless-related MMTV integration site 1 (mouse) |
Cre recombinase activity is expected in embryonic neural tube, midbrain, caudal diencephalon, the mid-hindbrain junction, dorsal spinal cord, and neural crest cells |
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