|Aged B6 mouse displaying graying coat and thinning hair.|
The normal coat color for the C57BL/6J mouse is non-agouti black with lighter (yellow/tan) hairs around ears, eyes, and the base of the tail; however, your aged cohort may display these natural characteristics of aging:
These are normal characteristics of aging and are expected in this colony.
|Aged B6 mouse displaying barbering.|
|Aged B6 mouse displaying barbered muzzle.|
In addition to normal characteristics seen as a result of aging (graying or thinning coat), certain characteristics are allowed in our aging colony after 25 weeks of age, including:
|Survival curve of C57BL/6J mice. Data are adapted from Yuan, et al. 2012 and are available in the Mouse Phenome Database.|
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The JAX Aging Center uses diverse expertise in biology and genomics on the problems and disorders associated with aging, building a better understanding of the molecular mechanisms at work in lifespan and health span. View publications featuring the aged B6 and other mouse models from JAX.
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Aging studies are lengthy, resource intensive, and require advance planning. This webinar highlights special considerations for maximizing the translational value of data collected from aged research mice.