|Aged B6 mouse displaying graying coat and thinning hair.|
The normal coat color for the C57BL/6J mouse is non-agouti black with lighter (yellow/tan) hairs around ears, eyes, and the base of the tail; however, your aged cohort may display these natural characteristics of aging:
These are normal characteristics of aging and are expected in this colony.
|Aged B6 mouse displaying barbering.|
|Aged B6 mouse displaying barbered muzzle.|
In addition to normal characteristics seen as a result of aging (graying or thinning coat), certain characteristics are allowed in our aging colony after 25 weeks of age, including:
Body weights of aged male and female mice are available.
|Survival curve of C57BL/6J mice. Data are adapted from Yuan, et al. 2012 and are available in the Mouse Phenome Database.|
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Oh YS, Seo EH, Lee YS ET AL. increase of Calcium Sensing Receptor Expression Is Related to Compensatory Insulin Secretion during Aging in Mice. PLoS One. 2016 Jul 21;11(7):e0159689. PMID: 27441644
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The JAX Aging Center uses diverse expertise in biology and genomics on the problems and disorders associated with aging, building a better understanding of the molecular mechanisms at work in lifespan and health span. View publications featuring the aged B6 and other mouse models from JAX.
Aging Research Data from the Mouse Phenome Database
The Mouse Phenome Database (MPD) is the major venue for public dissemination of data generated by the Nathan Shock Center’s Cores and outreach to the wider aging research community. MPD provides public access to median lifespan and Kaplan-Meier survival curves for males and females, as well as phenotypic and genotypic data for all strains.
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