Research Overview

Powerful genetic factors influence the biological mechanisms of addiction.

Research into the basic mechanisms of aging to find the genetic and physiological causes of age-related diseases and disorders.

JAX is developing new treatments and therapies based on precision modeling.

JAX has played a critical role in cancer and genetic research since 1929. 

Type 1 and type 2 diabetes have just two things in common: a shared name and insulin. 

We focus on several aspects of cardiovascular function, including early development, regeneration and the role of genetics in determining cholesterol levels.

JAX is thinking differently about how the body’s immune response and inflammation contribute to a variety of diseases, including cancer and diabetes.

JAX is using advanced sequencing techniques for infectious disease diagnostics and developing microbiome-based therapeutics for diseases.

Modern lifestyles have disrupted the equation, and metabolic disorders such as obesity, type 2 diabetes, and cardiovascular disease are at epidemic levels.

Rare diseases are not rare, more than 30 million people in the U.S. have a rare disease, for which there are no cures and few effective treatments.

Regenerative medicine is a relatively new field of study that treats injuries and diseases by harnessing the body’s own regenerative capabilities.

JAX research is exploring the complex genetics of infertility, birth defects and genetic diversity.