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Late-onset AD base models

MODELJAX #TYPEDESCRIPTIONNOMENCLATUREREFERENCE
LOAD1 = APOE4/Trem2*R47H28709compound KIAPOE4 & Trem2R47H KIB6(SJL)-Apoetm1.1(APOE*4)Adiuj Trem2em1Adiuj/JPMID:34707490
LOAD2 = Abeta/APOE4/Trem2*R47H30670compound KIHumanized Aβ1-42, APOE4 & Trem2R47H KIB6.Cg-Apoetm1.1(APOE*4)Adiuj Appem1Adiuj Trem2em1Adiuj/JPMID:38735056
LOAD3 = Abeta/APOE4/MAPT(H1.0)37778compound KIHumanized Aβ1-42, APOE4 & humanized TAU of H1 haplotypeB6(SJL)-Apoetm1.1(APOE*4)Adiuj Tc(HSA17)2Mdk Appem1Adiuj/J
Abeta/APOE434415compound KIHumanized Aβ1-42 & APOE4B6(SJL)-Apoetm1.1(APOE*4)AdiujAppem1Adiuj/J
Abeta/APOE334455compound KIHumanized Aβ1-42 & APOE3B6(SJL)-Apoeem2(APOE*)AdiujAppem1Adiuj/J
Abeta/MAPT(H1.0)38908compound KIHumanized Aβ1-42 & humanized TAU of H1 haplotypeB6.Cg-Tc(HSA17)2Mdk Appem1Adiuj/J
MAD138104compound KIHumanized floxed Aβ1-42, APOE4 & humanized TAU of H2.1 haplotypeB6.(Cg)-Apoetm1.1(APOE*4)AdiujTc(HSA17)1Mdk Apptm1.1Aduci/AduciJ
MAD238105compound KIHumanized floxed Aβ1-42 with Swedish and Iberian mutations, APOE4 & humanized TAU of H2.1 haplotypeB6.(Cg)-Apoetm1.1(APOE*4)AdiujTc(HSA17)1Mdk Appem2Aduci/AduciJ

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