Diversity Outbred

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    A diversity outbred F1 mouse model identifies host-intrinsic genetic regulators of response to immune checkpoint inhibitors
    Oncoimmunology. 2022 Apr 20;11(1):2064958. doi: 10.1080/2162402X.2022.2064958.
    PMID: 35481286

  • Bogue MA et al
    Collaborative Cross and Diversity Outbred data resources in the Mouse Phenome Database
    Mamm Genome
    . 2015; 26(9-10): 511–520. doi: 10.1007/s00335-015-9595-6
    PMID: 26286858 PMCID: PMC4602074
  • Chesler EJ et al
    Diversity Outbred mice at 21: Maintaining allelic variation in the face of selection
    G3 (Bethesda).
     2016 Dec 7;6(12):3893-3902. doi: 10.1534/g3.116.035527
    PMID: 27694113 PMCID: PMC5144960
  • Keller MP et al
    Genetic Drivers of Pancreatic Islet Function
    Genetics. 2018 May;209(1):335-356. doi: 10.1534/genetics.118.300864. Epub 2018 Mar 22
    PMID: 29567659 PMCID: PMC5937189 
  • Mayeux et al
    Silicosis and Silica-Induced Autoimmunity in the Diversity Outbred Mouse
    Front Immunol.
     2018 Apr 26;9:874. doi: 10.3389/fimmu.2018.00874. eCollection 2018.
    PMID: 29755467 PMCID: PMC5932595
  • Shorter JR et al
    Quantitative trait mapping in Diversity Outbred mice identifies two genomic regions associated with heart size
    Mamm Genome.
     2018 Feb;29(1-2):80-89. doi: 10.1007/s00335-017-9730-7. Epub 2017 Dec 26.
    PMID: 29279960
  • Winter et al
    Mapping Complex Traits in a Diversity Outbred F1 Mouse Population Identifies Germline Modifiers of Metastasis in Human Prostate Cancer
    Cell Syst.
     2017 Jan 25;4(1):31-45.e6. doi: 10.1016/j.cels.2016.10.018. Epub 2016 Dec 1.
    PMID: 27916600 PMCID: PMC5269474
  • Churchill GA et al
    The Collaborative Cross, a community resource for the genetic analysis of complex traits
    Nat Genet.
     2004 Nov;36(11):1133-7. doi: 10.1038/ng1104-1133
    PMID: 15514660
  • Graham JB et al
    Genetic diversity in the Collaborative Cross model recapitulates human West Nile virus disease outcomes
     2015 May 5;6(3):e00493-15. doi: 10.1128/mBio.00493-15.
    PMID: 25944860 PMCID: PMC4436067
  • Josset L et al
    Annotation of long non-coding RNAs expressed in Collaborative Cross founder mice in response to respiratory virus infection reveals a new class of interferon-stimulated transcripts
    RNA Biol.
     2014;11(7):875-90. doi: 10.4161/rna.29442. Epub 2014 Jun 12.
    PMID: 24922324 PMCID: PMC4179962
  • Levy R et al
    Collaborative Cross mice in a genetic association study reveal new candidate genes for bone microarchitecture
    BMC Genomics.
     2015 Nov 26;16:1013. doi: 10.1186/s12864-015-2213-x.
    PMID: 26611327 PMCID: PMC4661944
  • Smith CM et al
    Tuberculosis susceptibility and vaccine protection are independently controlled by host genotype
     2016 Sep 20;7(5). pii: e01516-16. doi: 10.1128/mBio.01516-16.
    PMID: 27651361 PMCID: PMC5030360
  • Srivastava A et al
    Genomes of the mouse Collaborative Cross
     2017 Jun;206(2):537-556. doi: 10.1534/genetics.116.198838.
    PMID: 28592495 PMCID: PMC5499171
  • Venkatratnam A et al
    Collaborative Cross mouse population enables refinements to characterization of the variability in toxicokinetics of trichloroethylene and provides genetic evidence for the role of PPAR pathway in Its oxidative metabolism
    Toxicol Sci.
     2017 Jul 1;158(1):48-62. doi: 10.1093/toxsci/kfx065.
    PMID: 28369613


  • Kannan S et al
    Systems genetics analysis of a recombinant inbred mouse cell culture panel reveals Wnt pathway member Lrp6 as a regulator of adult hippocampal precursor cell proliferation
    Stem Cells.
     2016 Mar;34(3):674-84. doi: 10.1002/stem.2313.
    PMID: 26840599
  • King R et al
    Genomic locus modulating IOP in the BXD mouse strains
    G3 (Bethesda).
     2018 May 4;8(5):1571-1578. doi: 10.1534/g3.118.200190.
    PMID: 29496776 PMCID: PMC5940149
  • Li H et al
    An integrated systems genetics and omics toolkit to probe gene function
    Cell Syst.
     2018 Jan 24;6(1):90-102.e4. doi: 10.1016/j.cels.2017.10.016. Epub 2017 Nov 30.
    PMID: 29199021
  • Neuner SM et al
    Systems genetics identifies Hp1bp3 as a novel modulator of cognitive aging
    Neurobiol Aging.
     2016 Oct;46:58-67. doi: 10.1016/j.neurobiolaging.2016.06.008. Epub 2016 Jun 17.
    PMID: 27460150 PMCID: PMC5018442
  • Philip VM et al
    High-throughput behavioral phenotyping in the expanded panel of BXD recombinant inbred strains
    Genes Brain Behav.
     2010 Mar 1;9(2):129-59. doi: 10.1111/j.1601-183X.2009.00540.x. Epub 2009 Sep 22.
    PMID: 19958391 PMCID: PMC2855868
  • Wang X et al
    Joint mouse-human phenome-wide association to test gene function and disease risk
    Nat Commun.
     2016 Feb 2;7:10464. doi: 10.1038/ncomms10464.
    PMID: 26833085 PMCID: PMC4740880