SETX L389S REV/REV

Product Code: JIPSC1340

Background

Genetics

Gene

SETX

Condition

Amyotrophic lateral sclerosis 4_ juvenile

Allele Charactertistics

Autosomal Recessive

View Information in ClinVar

Derived from Cell Line

JIPSC1324_SETX_L389S_SNV/SNV

Genomic Features

Genomic Coordinate (GRCh38)

chr9:132330432 (-)

dbSNP

rs29001584

Genomic Sequence

GTCCTAACATGTATGAAGAAATGGAAACAT[T/C]AGCCAGTGTACTTCAGTCAGATATTGGTCA
View With Genome Browser

Gene Editing Reagents

Nuclease

SpCas9

Protospacer Sequence

AATATCTGACTGAAGTACGC

Donor Template

GAGAACAGCCATTTGCCCAGATTATTGTCCTAACATGTATGAAGAAATGGAAACATTAGCCAGTGTACTTCAGTCAGATATTGGTCAAGACATGCGTGTT

DNA Primers for Sequence Validation

PCR Forward

CTTGGCACATTTGACGACGG

PCR Reverse

TGAACCTGTCATAAGTGGTGCT

Sanger Sequencing Primer