SETX L389S SNV/SNV

Product Code: JIPSC1324

Background

Genetics

Gene

SETX

Condition

Amyotrophic lateral sclerosis 4_ juvenile

Allele Charactertistics

Autosomal Recessive

View Information in ClinVar

Derived from Cell Line

JIPSC1000_KOLF2.1J

Genomic Features

Genomic Coordinate (GRCh38)

chr9:132330432 (-)

dbSNP

rs29001584

Genomic Sequence

GTCCTAACATGTATGAAGAAATGGAAACAT[T/C]AGCCAGTGTACTTCAGTCAGATATTGGTCA
View With Genome Browser

Gene Editing Reagents

Nuclease

SpCas9

Protospacer Sequence

AATATCTGACTGAAGTACAC

Donor Template

AACACGCATGTCTTGACCAATATCTGACTGAAGTACGCTGGCTGATGTTTCCATTTCTTCATACATGTTAGGACAATAATCTGGGCA

DNA Primers for Sequence Validation

PCR Forward

CTTGGCACATTTGACGACGG

PCR Reverse

TGAACCTGTCATAAGTGGTGCT

Sanger Sequencing Primer