ANXA11 G38R REV/WT

Product Code: JIPSC1210

Background

Genetics

Gene

ANXA11

Condition

Amyotrophic lateral sclerosis

Allele Charactertistics

Autosomal Dominant

View Information in ClinVar

Derived from Cell Line

JIPSC1188_ANXA11_G38R_SNV/WT

Genomic Features

Genomic Coordinate (GRCh38)

chr10:80170859 (-)

dbSNP

rs142083484

Genomic Sequence

TACCCTCCTCCGCCCAGCATGCCCCCCATC[G/A]GGCTGGATAACGTGGCCACCTATGCGGGGC
View With Genome Browser

Gene Editing Reagents

Nuclease

SpCas9

Protospacer Sequence

GGCCACGTTATCCAGCCTGA

Donor Template

GCTTTCAGGTGGTGGTCCCTGGGGAGGTGCTGCCTACCCTCCTCCGCCCAGCATGCCCCCCATCGGGCTGGATAACGTGGCCACCTATGCGGGGCAGTTC

DNA Primers for Sequence Validation

PCR Forward

GCAGAAGCCTGATGAAAACCC

PCR Reverse

TCATGTGGTCTGTGGTGTCC

Sanger Sequencing Primer