Retinal degeneration 9 rd9

Retinal degeneration 9 (Rd9)

Rd9 is an X-linked semi-dominant retinal degeneration model. In Rd9 mutants, the retina is covered with diffuse white spots (mottled). The fundus appears normal at weaning age, and the retina becomes mottled starting at 6 weeks of age in heterozygous females. The fundus of homozygous females and hemizygous males has a blond appearance. Retinal pigment loss and electroretinogram response decreases with age.