Eishani Sokolowski

As a Ph.D. Candidate, I am currently working on surveying the specific and shared responses of human pancreatic islets to pathophysiologic stressors related to type 2 diabetes (T2D), along with investigating how a 6-month intense lifestyle intervention can affect the peripheral blood mononuclear cells (PBMCs) of older individuals with T2D. I am leveraging large biological datasets obtained from multiple sequencing modalities (such as bulk RNA-seq, bulk ATAC-seq, scRNA-seq, and snATAC-seq) to uncover changes in the transcriptomic and epigenomic profiles of pancreatic islets and PBMCs.