JAX SOMASEQ™
Step into the future of oncology research with our next generation sequencing (NGS) assay. Unlock information behind 517 vital cancer-related genes, delving deep into the core of DNA and RNA variant exploration. Seamlessly uncover SNVs, CNVs, indels, and fusions, alongside comprehensive insights into MSI and TMB - all in a single, dynamic package.
- Provides median exon coverage ≥150X
- Detects SNVs and indels with variant allele fraction as low as 5%
- Identifies copy number alterations, including amplifications (≥5 copies) and deletions (≤1 copy)
- Includes biomarker report for tumor mutational burden and microsatellite instability
RNASEQ
Explore the full spectrum of gene expression with comprehensive transcriptome coverage. Our RNA-Seq technology offers unparalleled flexibility and scalability. Customize your experimental design to fit your research goals and scale up seamlessly for in-depth analyses across diverse biological contexts.
- Experience unmatched precision as our cutting-edge sequencing platform captures the full spectrum of RNA molecules.
- Evaluate the differences between non-responsive and responsive tumors in a single study arm.
- Choose desired coverage for your project!
Whole Exome Sequencing
Discover genetic variations amongst your study cohort from rare mutations to common polymorphisms using JAX APML's cutting edge technology combined with our analytics expertise.
- Evaluate the differences between non-responsive and responsive tumors in a single study arm.
- Detect key genomic alterations with the JAX APML exome pipeline.
- Choose desired coverage for your project!
Whole Genome Sequencing
From delving into rare disease to exploring therapeutic targets our whole genome sequencing service equips you with the data you need to drive research forward. State-of-the-art technology ensures accuracy and completeness.
- Identify a plethora of genetic variations that are crucial to understanding genetic diversity, inherited traits, and disease-related mutations.
- Choose desired coverage for your project!
*All services include subtraction of murine background.
Data Processing
To aid functional interpretation, detailed annotations of variants based on several genomic, functional, and population datasets including dbSNP, COSMIC, Ensembl, UCSC, the 1000 Genomes project, NHLBI Exome Sequencing Project (ESP), the Exome Aggregation Consortium (ExAC), PolyPhen, SIFT, PhyloP, and many more will be provided.