Well-Characterized Mouse Models

JAX® Mice are the best characterized and most widely used mice available. More than 80% of all mouse-related research publications that cite a strain source use JAX® Mice.

Data sets included in the physiological data summaries

Body weights

Many researchers use body weight as a basic indicator of mouse health and overall general condition, and sometimes as criteria for selecting the most appropriate strain for their studies.

Hematology profiles

Knowing the cellular components of blood allows researchers to assess animal health. The profiles include:

  • White blood cell (WBC) count
  • Red blood cell (RBC) count
  • Hemoglobin concentration
  • Hematocrit
  • Mean cell volume (MCV)
  • Mean cell hemoglobin concentration (MCHC)
  • Platelet count
  • Mean platelet volume (MPV)
  • Reticulocyte counts
  • Percent reticulocytes
  • Reticulocyte hemoglobin content
  • Neutrophil, lymphocyte, monocyte, eosinophil and basophil counts
  • Percent neutrophils, lymphocytes, monocytes, eosinophils and basophils

Serum biochemistry

Many scientists use serum biochemistry as a primary health indicator and to investigate commonly found disease states. Serum biochemistry data includes:

  • Albumin and total protein levels
  • Blood urea nitrogen (BUN)
  • Electrolytes (calcium, phosphorus)
  • Lipid levels (including cholesterol, high density lipoprotein cholesterol (HDLC), triglyceride, and free fatty acids)
  • Glucose (fed)
  • Alanine transferase (ALT),
  • Creatine kinase (CK)
  • Thyroxine (T4)

Organ weights

  • Brain
  • Heart
  • Liver
  • Kidneys
  • Spleen
  • Other

Body composition (DEXA Analysis)

  • Bone mineral density
  • Bone mineral content
  • Lean tissue
  • Fat tissue

Immunological profiles (Spleen analysis by Flow Cytometry)

  • Lymphoid cell percentages (including B cells, T cells, NK cells, NKT cells)
  • Myeloid cell percentages (granulocytes and monocytes)