Whether you need inbred, outbred, or B6J nude mice, JAX has you covered. Maintained at industry-leading health standards and competitively priced, JAX nude mice are the best route to getting your experimental data faster.
Mice homozygous for the Foxn1nu spontaneous mutation lack a transcriptional factor necessary for development of thymic epithelia and normal hair development. Mutants are athymic, preventing normal T cell development. B cell activity is limited to production of IgM due to a lack of functional CD4 helper T cells. Lack of functional CD8 T cells leads to a loss of T cell-mediated cytotoxic activity.
NSG™ mice (005557) are the most highly immunodeficient mice and the model of choice for cancer xenograft modeling, stem cell biology, humanized mice, and infectious disease research.
JAX maintains the largest repository of mouse models in the world - over 8,000 strains. Search the JAX Mice Database to find your mouse.
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