JAX Mouse Strain Datasheet - 005557

NOD.Cg-Prkdc^scid Il2rg^tm1Wjl/SzJ

Stock No:: 005557 |; NSG

Readily Available

Overview

Also Known As: NOD scid gamma, NOD-scid IL2Rg^null, NOD-scid IL2Rgamma^null, NSG

These mice are most often referred to using their branded name "NSG™" and are extremely immunodeficient. The mice carry two mutations on the NOD/ShiLtJ genetic background; severe combined immune deficiency (scid) and a complete null allele of the IL2 receptor common gamma chain (IL2rg^null). The scid mutation is in the DNA repair complex protein Prkdc and renders the mice B and T cell deficient. The IL2rg^null mutation prevents cytokine signaling through multiple receptors, leading to a deficiency in functional NK cells. The severe immunodeficiency allows the mice to be humanized by engraftment of human CD34+ hematopoietic stem cells (HSC), peripheral blood mononuclear cells (PBMC), patient derived xenografts (PDX), or adult stem cells and tissues. The immunodeficient NSG mice enable research in human immune function, infectious disease, diabetes, oncology, and stem cell biology.

Donating Investigator

Dr. Leonard D. Shultz, The Jackson Laboratory

Genetic overview

Genetic Background	Generation
	N8F?+4pF24 (14-AUG-14)

Il2rg^tm1Wjl

Allele Type	Gene Symbol	Gene Name
Targeted (Null/Knockout)	Il2rg	interleukin 2 receptor, gamma chain

Prkdc^scid

Allele Type	Gene Symbol	Gene Name
Spontaneous	Prkdc	protein kinase, DNA activated, catalytic polypeptide

View Genetics

Research Applications

Research Tools
Cancer Research
Immunology, Inflammation and Autoimmunity Research
Internal/Organ Research
Virology Research

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Base Price

Starting at:

$170.00 Domestic price for male 3-week

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Volume Pricing Available!

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Details

Important Note

Like its parental strain, NOD/ShiLtJ (Stock No. 001976), NSG mice exhibit a progressive hearing loss that is already severe by three months of age.

Detailed Description

The NOD.Cg-Prkdc^scid Il2rg^tm1Wjl/SzJ mice, most often known by their branded name, NOD scid gamma (NSG™), do not express the Prkdc gene nor the X-linked Il2rg gene. NSG mice are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities. Histological examination of lymphoid tissues reveals absence of lymphoid cells and some cystic structures in the thymus, an absence of follicles in the spleen and markedly diminished celluarity of lymph nodes. NSG mice are deficient in mature lymphocytes, serum Ig is not detectable and natural killer (NK) cell cytotoxic activity is extremely low. These mice are resistant to lymphoma development even after sublethal irradiation treatment. These mutant mice have been shown to readily support engraftment of human CD34⁺ hematopoietic stem cells and represent a superior, long-lived model suitable for studies employing xenotransplantation strategies. NSG mice are highly sensitive to the diabetogenic effects of streptozotocin (STZ). The NSG-STZ preclinical model for pancreatic islet transplantation is now available from JAX® Services . Please note that the NSG carries the true null interleukin-2 receptor gamma chain mutation and should not be confused with other strains that express a truncated interleukin-2 receptor gamma chain as described in: "Modulation of hematopoiesis in mice with a truncated mutant of the interleukin-2 receptor gamma chain" Ohbo K et al. Blood 1996. 87:956-67.

View our Resources for the NSG™ mouse model, including,

NSG™ Mouse Model Portfolio
Housing and Breeding Considerations for NSG™ Mice
Frequently Asked NSG™ Questions
Breakthrough Research Using NSG™
Immunodeficient Mouse and Xenograft Host Comparisons
Flow Cytometry Characterization Data for Immunodeficient JAX Strains

Development

These double mutant mice were produced by breeding female NOD.CB17-Prkdc^scid/J (Stock No. 001303) mice with male mice bearing the X-linked B6.129S4-Il2rg^tm1Wjl/J allele (Stock No. 003174). The resulting male mice heterozygous for the Prkdc^scid allele and hemizygous for the Il2rg^tm1Wjl allele were crossed to female NOD.CB17-Prkdc^scid/J (Stock No. 001303) mice for eight generations. Heterozygotes were interbred to produce mice homozygous for the Prkdc^scid allele and homozygous (females) or hemizygous (males) for the Il2rg^tm1Wjl allele.

Control Suggestions

Additional Information

Considerations for Choosing Controls

Selected References

Coughlan AM; Harmon C; Whelan S; O'Brien EC; O'Reilly VP; Crotty P; Kelly P; Ryan M; Hickey FB; O'Farrelly C; Little MA. 2016. Myeloid Engraftment in Humanized Mice: Impact of Granulocyte-Colony Stimulating Factor Treatment and Transgenic Mouse Strain.. In: . . MGI: J:230785
Shultz LD; Lyons BL; Burzenski LM; Gott B; Chen X; Chaleff S; Kotb M; Gillies SD; King M; Mangada J; Greiner DL; Handgretinger R. 2005. Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells.. In: . . MGI: J:109833

View All References

Genetics

Il2rg^tm1Wjl

Allele Symbol: Il2rg^tm1Wjl

Allele Name	targeted mutation 1, Warren J Leonard
Allele Type	Targeted (Null/Knockout)
Allele Synonym(s)	CD132^-; IL2Rgamma^null; Il2rg^tm1Wjll; [KO]gammac; gammac^-; gc^-
Gene Symbol and Name	Il2rg, interleukin 2 receptor, gamma chain
Gene Synonym(s)	Ab2-183; CD132; CIDX; Cd132; IL-2RG; IMD4; P64; SCIDX; SCIDX1; [g]c; common cytokine receptor gamma chain; common gamma chain; gamma C receptor; gamma(c); gammaC; gc
Site of Expression	Primarily lymphoid cells.
Strain of Origin	129S4/SvJae
Chromosome	X
Molecular Note	A neomycin resistance cassette replaced part of exon 3 and all of exons 4 - 8 of the gene, resulting in the loss of most of the extracellular domain and all of the transmembrane and cytoplasmic domains of the protein.
Mutations Made By	Dr. Warren Leonard, NHLBI, NIH

Prkdc^scid

Allele Symbol: Prkdc^scid

Allele Name	severe combined immunodeficiency
Allele Type	Spontaneous
Allele Synonym(s)	SCID; scid
Gene Symbol and Name	Prkdc, protein kinase, DNA activated, catalytic polypeptide
Gene Synonym(s)	AI326420; AU019811; DNA-PK; DNA-PKcs; DNAPDcs; DNAPK; DNPK1; DOXNPH; HYRC; HYRC1; IMD26; XRCC7; doxorubicin nephropathy; dxnph; dxnph; expressed sequence AI326420; expressed sequence AU019811; p350; scid; severe combined immunodeficiency; slip
Site of Expression	T and B lymphocytes.
Strain of Origin	C.B-17
Chromosome	16
Molecular Note	A T-to-A transversion point mutation at a position corresponding to codon 4095 created a premature stop codon.

Disease/Phenotype

Disease Terms

Research Areas By Genotype

This mouse can be used to support research in many areas including:

Research Tools
- Immunology, Inflammation and Autoimmunity Research
  - B, T, and NK cell deficiency
- Infectious Disease
  - HIV

Genotype: Il2rg^tm1Wjl related

Cancer Research
- Growth Factors/Receptors/Cytokines
Immunology, Inflammation and Autoimmunity Research
- Growth Factors/Receptors/Cytokines

Genotype: Prkdc^scid related

Immunology, Inflammation and Autoimmunity Research
- Immunodeficiency
  - B and T cell deficiency
Internal/Organ Research
- Lymphoid Tissue Defects
  - B and T cell deficiency
Research Tools
- Cancer Research
  - B and T cell deficiency, xenograft/transplant host
- Toxicology Research
  - xenograft/transplant host
Virology Research
- B and T Cell Deficiency
  - AIDS research tool

Mammalian Phenotype Terms by Genotype

Genotype: Il2rg^tm1Wjl/Il2rg^tm1Wjl Prkdc^scid/Prkdc^scid
NOD.Cg-Prkdc^scid Il2rg^tm1Wjl/Sz

mortality/aging

premature death
- median survival time is lengthened to between 59-95 weeks (median 89 weeks) in contrast to the shorter lifespan observed homozygous Prkdc^scid controls
- the majority of autopsies indicate no evidence of lymphomas

immune system phenotype

abnormal immune system organ morphology
- lymph tissues are severely depleted of lymphoid cells

abnormal response to transplant
- human CD45+ cells comprise almost 50% of cells in the spleen, approximately 35% in bone marrow and thymus, and 6% in blood at 10 weeks post-engraftment
- mice support CD34+ human stem cell engraftment at much higher levels than Prkdc^scid controls

abnormal spleen B cell follicle morphology
- spleens do not have detectable follicles

abnormal splenic cell ratio
- two fold reduction in nucleated spleen cell numbers in comparison to Prkdc^scid controls

abnormal thymus morphology
- thymus consists mostly of stromal cells with sporadic cyst structures

decreased CD4-positive, alpha beta T cell number
- spleens are deficient in mature T cells

decreased CD8-positive, alpha-beta T cell number
- spleens are deficient in mature T cells

decreased NK cell number
- mice are deficient in cells expressing NK cell markers in comparison to Prkdc^scid controls
- spleen cells from poly(I:C) stimulated 6-8 week old mice exhibit very low levels of NK cell cytotoxic activity

decreased immature B cell number
- flow cytometric analysis indicates that spleen cells exhibit a reduction in B220+ IgK- immature B cells in comparison to Prkdc^scid controls

decreased immunoglobulin level
- no detectable immunoglobulin in mice at 394-426 days of age

decreased leukocyte cell number
- decrease in peripheral leukocytes at 10 weeks as compared to to Prkdc^scid controls

decreased mature B cell number
- spleens are deficient in B220+ IgK+ B cells

lymph node hypoplasia
- lymph nodes are hypocellular

small lymph nodes
- lymph nodes in the double mutant are markedly smaller than those of homozygous Prkdc^scid mice

thymus cysts
- sporadic cyst structures

hematopoietic system phenotype

abnormal spleen B cell follicle morphology
- spleens do not have detectable follicles

abnormal splenic cell ratio
- two fold reduction in nucleated spleen cell numbers in comparison to Prkdc^scid controls

abnormal thymus morphology
- thymus consists mostly of stromal cells with sporadic cyst structures

decreased CD4-positive, alpha beta T cell number
- spleens are deficient in mature T cells

decreased CD8-positive, alpha-beta T cell number
- spleens are deficient in mature T cells

decreased NK cell number
- mice are deficient in cells expressing NK cell markers in comparison to Prkdc^scid controls
- spleen cells from poly(I:C) stimulated 6-8 week old mice exhibit very low levels of NK cell cytotoxic activity

decreased immature B cell number
- flow cytometric analysis indicates that spleen cells exhibit a reduction in B220+ IgK- immature B cells in comparison to Prkdc^scid controls

decreased immunoglobulin level
- no detectable immunoglobulin in mice at 394-426 days of age

decreased leukocyte cell number
- decrease in peripheral leukocytes at 10 weeks as compared to to Prkdc^scid controls

decreased mature B cell number
- spleens are deficient in B220+ IgK+ B cells

decreased mean corpuscular volume
- slight decrease in packed cell volume at 10 weeks as compared to to Prkdc^scid controls

thymus cysts
- sporadic cyst structures

cellular phenotype

increased cellular sensitivity to X-ray irradiation
- mice do not survive doses above or equal to 400cGy

neoplasm

decreased incidence of tumors by ionizing radiation induction
- mice irradiated with doses below 400cGy do not exhibit thymic lymphomas in contrast to homozygous Prkdc^scid controls

homeostasis/metabolism phenotype

abnormal glucose homeostasis
- streptozotocin-diabetic mice are not restored to euglycemia after receiving transplants of 1000 to 3000 IEQ, while 4000 IEQ transplant was successful in two long-term survivors

hyperglycemia
- streptozotocin effectively induced hyperglycemia essentially equally in male and female mice at doses of 120to 160 mg/kg; some mice do not become hyperglycemic at all doses of streptozotocin administered

endocrine/exocrine gland phenotype

abnormal thymus morphology
- thymus consists mostly of stromal cells with sporadic cyst structures

thymus cysts
- sporadic cyst structures

Genotype: Il2rg^tm1Wjl/Y Prkdc^scid/Prkdc^scid
NOD.Cg-Prkdc^scid Il2rg^tm1Wjl/Sz

mortality/aging

premature death
- median survival time is lengthened to between 59-95 weeks (median 89 weeks) in contrast to the shorter lifespan observed homozygous Prkdc^scid controls
- the majority of autopsies indicate no evidence of lymphomas

cellular phenotype

increased cellular sensitivity to X-ray irradiation
- mice do not survive doses above or equal to 400cGy

hematopoietic system phenotype

abnormal spleen B cell follicle morphology
- spleens do not have detectable follicles

abnormal splenic cell ratio
- two fold reduction in nucleated spleen cell numbers in comparison to Prkdc^scid controls

abnormal thymus morphology
- thymus consists mostly of stromal cells with sporadic cyst structures

decreased CD4-positive, alpha beta T cell number
- spleens are deficient in mature T cells

decreased CD8-positive, alpha-beta T cell number
- spleens are deficient in mature T cells

decreased NK cell number
- mice are deficient in cells expressing NK cell markers in comparison to Prkdc^scid controls
- spleen cells from poly(I:C) stimulated 6-8 week old mice exhibit very low levels of NK cell cytotoxic activity

decreased immature B cell number
- flow cytometric analysis indicates that spleen cells exhibit a reduction in B220+ IgK- immature B cells in comparison to Prkdc^scid controls

decreased immunoglobulin level
- no detectable immunoglobulin in mice at 394-426 days of age

decreased leukocyte cell number
- decrease in peripheral leukocytes at 10 weeks as compared to to Prkdc^scid controls

decreased mature B cell number
- spleens are deficient in B220+ IgK+ B cells

decreased mean corpuscular volume
- slight decrease in packed cell volume at 10 weeks as compared to to Prkdc^scid controls

immune system phenotype

abnormal immune system organ morphology
- lymph tissues are severely depleted of lymphoid cells

abnormal response to transplant
- CD4:CD8 human T cell ratios that are close to normal physiological values and high levels of human B cells are observed in spleens of mice compared to NOD.CB17-Prkdc^scid mice
- engraftment of human lymphohematopoietic cells in blood and thymus, and peripheral blood mononuclear cells (PMBC) engraftment are higher than in NOD.CB17-Prkdc^scid
- human CD45+ cells comprise almost 50% of cells in the spleen, approximately 35% in bone marrow and thymus, and 6% in blood at 10 weeks post-engraftment
- irradiated mice engrafted with human hematopoietic stem cells (HSCs) show much greater engraftment of human hematopoietic cells at 12 weeks than control NOD.129S7(B6)-Rag1^tm1Mom homozygotes
- levels of human CD45+ cell and CD3+ T cell engraftment are higher in spleens than in NOD.CB17-Prkdc^scid mice
- mice support CD34+ human stem cell engraftment at much higher levels than Prkdc^scid controls
- percentages of human CD45+ cells engrafted in bone marrow are higher than in NOD.CB17-Prkdc^scid mice

abnormal spleen B cell follicle morphology
- spleens do not have detectable follicles

abnormal splenic cell ratio
- two fold reduction in nucleated spleen cell numbers in comparison to Prkdc^scid controls

abnormal thymus morphology
- thymus consists mostly of stromal cells with sporadic cyst structures

decreased CD4-positive, alpha beta T cell number
- spleens are deficient in mature T cells

decreased CD8-positive, alpha-beta T cell number
- spleens are deficient in mature T cells

decreased NK cell number
- mice are deficient in cells expressing NK cell markers in comparison to Prkdc^scid controls
- spleen cells from poly(I:C) stimulated 6-8 week old mice exhibit very low levels of NK cell cytotoxic activity

decreased immature B cell number
- flow cytometric analysis indicates that spleen cells exhibit a reduction in B220+ IgK- immature B cells in comparison to Prkdc^scid controls

decreased immunoglobulin level
- no detectable immunoglobulin in mice at 394-426 days of age

decreased leukocyte cell number
- decrease in peripheral leukocytes at 10 weeks as compared to to Prkdc^scid controls

decreased mature B cell number
- spleens are deficient in B220+ IgK+ B cells

lymph node hypoplasia
- lymph nodes are hypocellular

small lymph nodes
- lymph nodes in the double mutant are markedly smaller than those of homozygous Prkdc^scid mice

endocrine/exocrine gland phenotype

abnormal thymus morphology
- thymus consists mostly of stromal cells with sporadic cyst structures

Phenotype Information

Body Weight Information - JAX^® Mice Strain NOD.Cg-Prkdc^scid Il2rg^tm1Wyl/SzJ (005557)

JAX^® Physiological Data Summary [pdf]

References

Coughlan AM; Harmon C; Whelan S; O'Brien EC; O'Reilly VP; Crotty P; Kelly P; Ryan M; Hickey FB; O'Farrelly C; Little MA. 2016. Myeloid Engraftment in Humanized Mice: Impact of Granulocyte-Colony Stimulating Factor Treatment and Transgenic Mouse Strain.. In: . . MGI: J:230785
Shultz LD; Lyons BL; Burzenski LM; Gott B; Chen X; Chaleff S; Kotb M; Gillies SD; King M; Mangada J; Greiner DL; Handgretinger R. 2005. Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells.. In: . . MGI: J:109833

Additional References

Agliano A; Martin-Padura I; Mancuso P; Marighetti P; Rabascio C; Pruneri G; Shultz LD; Bertolini F. 2008. Human acute leukemia cells injected in NOD/LtSz-scid/IL-2Rgamma null mice generate a faster and more efficient disease compared to other NOD/scid-related strains.. In: . . MGI: J:142410
Banerjee P; Tripp A; Lairmore MD; Crawford L; Sieburg M; Ramos JC; Harrington W Jr; Beilke MA; Feuer G. 2010. Adult T-cell leukemia/lymphoma development in HTLV-1-infected humanized SCID mice.. In: . . MGI: J:162610
Boitano AE; Wang J; Romeo R; Bouchez LC; Parker AE; Sutton SE; Walker JR; Flaveny CA; Perdew GH; Denison MS; Schultz PG; Cooke MP. 2010. Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells.. In: . . MGI: J:167433
Chen Q; Khoury M; Chen J. 2009. Expression of human cytokines dramatically improves reconstitution of specific human-blood lineage cells in humanized mice.. In: . . MGI: J:155817
Distler E; Wolfel C; Kohler S; Nonn M; Kaus N; Schnurer E; Meyer RG; Wehler TC; Huber C; Wolfel T; Hartwig UF; Herr W. 2008. Acute myeloid leukemia (AML)-reactive cytotoxic T lymphocyte clones rapidly expanded from CD8(+) CD62L((high)+) T cells of healthy donors prevent AML engraftment in NOD/SCID IL2Rgamma(null) mice.. In: . . MGI: J:150330
Doulatov S; Notta F; Eppert K; Nguyen LT; Ohashi PS; Dick JE. 2010. Revised map of the human progenitor hierarchy shows the origin of macrophages and dendritic cells in early lymphoid development.. In: . . MGI: J:162608
Giassi LJ; Pearson T; Shultz LD; Laning J; Biber K; Kraus M; Woda BA; Schmidt MR; Woodland RT; Rossini AA; Greiner DL. 2008. Expanded CD34+ human umbilical cord blood cells generate multiple lymphohematopoietic lineages in NOD-scid IL2rgamma(null) mice.. In: . . MGI: J:150337
Goldstein AS; Huang J; Guo C; Garraway IP; Witte ON. 2010. Identification of a cell of origin for human prostate cancer.. In: . . MGI: J:162606
Gorantla S; Makarov E; Finke-Dwyer J; Gebhart CL; Domm W; Dewhurst S; Gendelman HE; Poluektova LY. 2010. CD8+ cell depletion accelerates HIV-1 immunopathology in humanized mice.. In: . . MGI: J:161304
Hayakawa J; Hsieh MM; Uchida N; Phang O; Tisdale JF. 2009. Busulfan produces efficient human cell engraftment in NOD/LtSz-Scid IL2Rgamma(null) mice.. In: . . MGI: J:150336
Heaney NB; Pellicano F; Zhang B; Crawford L; Chu S; Kazmi SM; Allan EK; Jorgensen HG; Irvine AE; Bhatia R; Holyoake TL. 2010. Bortezomib induces apoptosis in primitive chronic myeloid leukemia cells including LTC-IC and NOD/SCID repopulating cells.. In: . . MGI: J:162612
Holt N; Wang J; Kim K; Friedman G; Wang X; Taupin V; Crooks GM; Kohn DB; Gregory PD; Holmes MC; Cannon PM. 2010. Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo.. In: . . MGI: J:162607
Ishikawa F; Niiro H; Iino T; Yoshida S; Saito N; Onohara S; Miyamoto T; Minagawa H; Fujii S; Shultz LD; Harada M; Akashi K. 2007. The developmental program of human dendritic cells is operated independently of conventional myeloid and lymphoid pathways.. In: . . MGI: J:150332
Ishikawa F; Saito Y; Yoshida S; Harada M; Shultz LD. 2008. The differentiative and regenerative properties of human hematopoietic stem/progenitor cells in NOD-SCID/IL2rgamma(null) mice.. In: . . MGI: J:151387
Ishikawa F; Shimazu H; Shultz LD; Fukata M; Nakamura R; Lyons B; Shimoda K; Shimoda S; Kanemaru T; Nakamura K; Ito H; Kaji Y; Perry AC; Harada M. 2006. Purified human hematopoietic stem cells contribute to the generation of cardiomyocytes through cell fusion.. In: . . MGI: J:150333
Ishikawa F; Yasukawa M; Lyons B; Yoshida S; Miyamoto T; Yoshimoto G; Watanabe T; Akashi K; Shultz LD; Harada M. 2005. Development of functional human blood and immune systems in NOD/SCID/IL2 receptor {gamma} chain(null) mice.. In: . . MGI: J:142411
Ishikawa F; Yoshida S; Saito Y; Hijikata A; Kitamura H; Tanaka S; Nakamura R; Tanaka T; Tomiyama H; Saito N; Fukata M; Miyamoto T; Lyons B; Ohshima K; Uchida N; Taniguchi S; Ohara O; Akashi K; Harada M; Shultz LD. 2007. Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region.. In: . . MGI: J:150331
Jaiswal S; Jamieson CH; Pang WW; Park CY; Chao MP; Majeti R; Traver D; van Rooijen N; Weissman IL. 2009. CD47 is upregulated on circulating hematopoietic stem cells and leukemia cells to avoid phagocytosis.. In: . . MGI: J:151391
Jaiswal S; Pearson T; Friberg H; Shultz LD; Greiner DL; Rothman AL; Mathew A. 2009. Dengue virus infection and virus-specific HLA-A2 restricted immune responses in humanized NOD-scid IL2rgammanull mice.. In: . . MGI: J:154110
Janes MR; Limon JJ; So L; Chen J; Lim RJ; Chavez MA; Vu C; Lilly MB; Mallya S; Ong ST; Konopleva M; Martin MB; Ren P; Liu Y; Rommel C; Fruman DA. 2010. Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor.. In: . . MGI: J:162611
King M; Pearson T; Rossini AA; Shultz LD; Greiner DL. 2008. Humanized mice for the study of type 1 diabetes and beta cell function.. In: . . MGI: J:151393
King M; Pearson T; Shultz LD; Leif J; Bottino R; Trucco M; Atkinson MA; Wasserfall C; Herold KC; Woodland RT; Schmidt MR; Woda BA; Thompson MJ; Rossini AA; Greiner DL. 2008. A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene.. In: . . MGI: J:131635
King MA; Covassin L; Brehm MA; Racki W; Pearson T; Leif J; Laning J; Fodor W; Foreman O; Burzenski L; Chase TH; Gott B; Rossini AA; Bortell R; Shultz LD; Greiner DL. 2009. Human peripheral blood leucocyte non-obese diabetic-severe combined immunodeficiency interleukin-2 receptor gamma chain gene mouse model of xenogeneic graft-versus-host-like disease and the role of host major histocompatibility complex.. In: . . MGI: J:151390
Kong Y; Yoshida S; Saito Y; Doi T; Nagatoshi Y; Fukata M; Saito N; Yang SM; Iwamoto C; Okamura J; Liu KY; Huang XJ; Lu DP; Shultz LD; Harada M; Ishikawa F. 2008. CD34+CD38+CD19+ as well as CD34+CD38-CD19+ cells are leukemia-initiating cells with self-renewal capacity in human B-precursor ALL.. In: . . MGI: J:150329
Koo GC; Hasan A; O'Reilly RJ. 2009. Use of humanized severe combined immunodeficient mice for human vaccine development.. In: . . MGI: J:151535
Kumar P; Ban HS; Kim SS; Wu H; Pearson T; Greiner DL; Laouar A; Yao J; Haridas V; Habiro K; Yang YG; Jeong JH; Lee KY; Kim YH; Kim SW; Peipp M; Fey GH; Manjunath N; Shultz LD; Lee SK; Shankar P. 2008. T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice.. In: . . MGI: J:142409
Lepus CM; Gibson TF; Gerber SA; Kawikova I; Szczepanik M; Hossain J; Ablamunits V; Kirkiles-Smith N; Herold KC; Donis RO; Bothwell AL; Pober JS; Harding MJ. 2009. Comparison of human fetal liver, umbilical cord blood, and adult blood hematopoietic stem cell engraftment in NOD-scid/gammac-/-, Balb/c-Rag1-/-gammac-/-, and C.B-17-scid/bg immunodeficient mice.. In: . . MGI: J:156922
Libby SJ; Brehm MA; Greiner DL; Shultz LD; McClelland M; Smith KD; Cookson BT; Karlinsey JE; Kinkel TL; Porwollik S; Canals R; Cummings LA; Fang FC. 2010. Humanized nonobese diabetic-scid IL2rgammanull mice are susceptible to lethal Salmonella Typhi infection.. In: . . MGI: J:163745
Liu C; Chen BJ; Deoliveira D; Sempowski GD; Chao NJ; Storms RW. 2010. Progenitor cell dose determines the pace and completeness of engraftment in a xenograft model for cord blood transplantation.. In: . . MGI: J:167432
Majeti R; Chao MP; Alizadeh AA; Pang WW; Jaiswal S; Gibbs KD Jr; van Rooijen N; Weissman IL. 2009. CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells.. In: . . MGI: J:151392
Majeti R; Park CY; Weissman IL. 2007. Identification of a hierarchy of multipotent hematopoietic progenitors in human cord blood.. In: . . MGI: J:142413
Marodon G; Desjardins D; Mercey L; Baillou C; Parent P; Manuel M; Caux C; Bellier B; Pasqual N; Klatzmann D. 2009. High diversity of the immune repertoire in humanized NOD.SCID.gamma c-/- mice.. In: . . MGI: J:156921
Maykel J; Liu JH; Li H; Shultz LD; Greiner DL; Houghton J. 2014. NOD-scidIl2rg (tm1Wjl) and NOD-Rag1 (null) Il2rg (tm1Wjl) : a model for stromal cell-tumor cell interaction for human colon cancer.. In: . . MGI: J:227975
Medyouf H; Gao X; Armstrong F; Gusscott S; Liu Q; Gedman AL; Matherly LH; Schultz KR; Pflumio F; You MJ; Weng AP. 2010. Acute T-cell leukemias remain dependent on Notch signaling despite PTEN and INK4A/ARF loss.. In: . . MGI: J:157729
Morisot S; Wayne AS; Bohana-Kashtan O; Kaplan IM; Gocke CD; Hildreth R; Stetler-Stevenson M; Walker RL; Davis S; Meltzer PS; Wheelan SJ; Brown P; Jones RJ; Shultz LD; Civin CI. 2010. High frequencies of leukemia stem cells in poor-outcome childhood precursor-B acute lymphoblastic leukemias.. In: . . MGI: J:165977
Mota J; Rico-Hesse R. 2009. Humanized mice show clinical signs of dengue fever according to infecting virus genotype.. In: . . MGI: J:153922
Pearson T; Greiner DL; Shultz LD. 2008. Creation of 'humanized' mice to study human immunity.. In: . . MGI: J:151386
Pearson T; Shultz LD; Lief J; Burzenski L; Gott B; Chase T; Foreman O; Rossini AA; Bottino R; Trucco M; Greiner DL. 2008. A new immunodeficient hyperglycaemic mouse model based on the Ins2 ( Akita ) mutation for analyses of human islet and beta stem and progenitor cell function.. In: . . MGI: J:138005
Pearson T; Shultz LD; Miller D; King M; Laning J; Fodor W; Cuthbert A; Burzenski L; Gott B; Lyons B; Foreman O; Rossini AA; Greiner DL. 2008. Non-obese diabetic-recombination activating gene-1 (NOD-Rag1 null) interleukin (IL)-2 receptor common gamma chain (IL2r gamma null) null mice: a radioresistant model for human lymphohaematopoietic engraftment.. In: . . MGI: J:140388
Quintana E; Shackleton M; Sabel MS; Fullen DR; Johnson TM; Morrison SJ. 2008. Efficient tumour formation by single human melanoma cells.. In: . . MGI: J:142408
Rowe J; Greenblatt RJ; Liu D; Moffat JF. 2010. Compounds that target host cell proteins prevent varicella-zoster virus replication in culture, ex vivo, and in SCID-Hu mice.. In: . . MGI: J:162609
Sanchez PV; Perry RL; Sarry JE; Perl AE; Murphy K; Swider CR; Bagg A; Choi JK; Biegel JA; Danet-Desnoyers G; Carroll M. 2009. A robust xenotransplantation model for acute myeloid leukemia.. In: . . MGI: J:156920
Shultz LD; Ishikawa F; Greiner DL. 2007. Humanized mice in translational biomedical research.. In: . . MGI: J:142414
Shultz LD; Pearson T; King M; Giassi L; Carney L; Gott B; Lyons B; Rossini AA; Greiner DL. 2007. Humanized NOD/LtSz-scid IL2 receptor common gamma chain knockout mice in diabetes research.. In: . . MGI: J:151394
Shultz LD; Saito Y; Najima Y; Tanaka S; Ochi T; Tomizawa M; Doi T; Sone A; Suzuki N; Fujiwara H; Yasukawa M; Ishikawa F. 2010. Generation of functional human T-cell subsets with HLA-restricted immune responses in HLA class I expressing NOD/SCID/IL2r gamma(null) humanized mice.. In: . . MGI: J:162315
Simpson-Abelson MR; Sonnenberg GF; Takita H; Yokota SJ; Conway TF Jr; Kelleher RJ Jr; Shultz LD; Barcos M; Bankert RB. 2008. Long-term engraftment and expansion of tumor-derived memory T cells following the implantation of non-disrupted pieces of human lung tumor into NOD-scid IL2Rgamma(null) mice.. In: . . MGI: J:142412
Strowig T; Chijioke O; Carrega P; Arrey F; Meixlsperger S; Ramer PC; Ferlazzo G; Munz C. 2010. Human NK cells of mice with reconstituted human immune system components require preactivation to acquire functional competence.. In: . . MGI: J:167434
Strowig T; Gurer C; Ploss A; Liu YF; Arrey F; Sashihara J; Koo G; Rice CM; Young JW; Chadburn A; Cohen JI; Munz C. 2009. Priming of protective T cell responses against virus-induced tumors in mice with human immune system components.. In: . . MGI: J:149509
Unsinger J; McDonough JS; Shultz LD; Ferguson TA; Hotchkiss RS. 2009. Sepsis-induced human lymphocyte apoptosis and cytokine production in 'humanized' mice.. In: . . MGI: J:151270
Vlad G; Stokes MB; Liu Z; Chang CC; Sondermeijer H; Vasilescu ER; Colovai AI; Berloco P; D'Agati VD; Ratner L; Cortesini R; Suciu-Foca N. 2009. Suppression of xenogeneic graft-versus-host disease by treatment with immunoglobulin-like transcript 3-Fc.. In: . . MGI: J:156923
Wunderlich M; Chou FS; Link KA; Mizukawa B; Perry RL; Carroll M; Mulloy JC. 2010. AML xenograft efficiency is significantly improved in NOD/SCID-IL2RG mice constitutively expressing human SCF, GM-CSF and IL-3.. In: . . MGI: J:166359
le Viseur C; Hotfilder M; Bomken S; Wilson K; Rottgers S; Schrauder A; Rosemann A; Irving J; Stam RW; Shultz LD; Harbott J; Jurgens H; Schrappe M; Pieters R; Vormoor J. 2008. In childhood acute lymphoblastic leukemia, blasts at different stages of immunophenotypic maturation have stem cell properties.. In: . . MGI: J:150328

Additional - Il2rg^tm1Wjl related

Accardi R; Gruffat H; Sirand C; Fusil F; Gheit T; Hernandez-Vargas H; Le Calvez-Kelm F; Traverse-Glehen A; Cosset FL; Manet E; Wild CP; Tommasino M. 2015. The mycotoxin aflatoxin B1 stimulates Epstein-Barr virus-induced B-cell transformation in in vitro and in vivo experimental models.. In: . . MGI: J:226625
Agliano A; Martin-Padura I; Mancuso P; Marighetti P; Rabascio C; Pruneri G; Shultz LD; Bertolini F. 2008. Human acute leukemia cells injected in NOD/LtSz-scid/IL-2Rgamma null mice generate a faster and more efficient disease compared to other NOD/scid-related strains.. In: . . MGI: J:142410
Akkina R; Berges BK; Palmer BE; Remling L; Neff CP; Kuruvilla J; Connick E; Folkvord J; Gagliardi K; Kassu A; Akkina SR. 2011. Humanized Rag1gammac Mice Support Multilineage Hematopoiesis and Are Susceptible to HIV-1 Infection via Systemic and Vaginal Routes.. In: . . MGI: J:174292
Al-Shami A; Spolski R; Kelly J; Fry T; Schwartzberg PL; Pandey A; Mackall CL; Leonard WJ. 2004. A role for thymic stromal lymphopoietin in CD4(+) T cell development.. In: . . MGI: J:108209
Ali N; Flutter B; Sanchez Rodriguez R; Sharif-Paghaleh E; Barber LD; Lombardi G; Nestle FO. 2012. Xenogeneic graft-versus-host-disease in NOD-scid IL-2Rgammanull mice display a T-effector memory phenotype.. In: . . MGI: J:191672
Amarnath S; Foley JE; Farthing DE; Gress RE; Laurence A; Eckhaus MA; Metais JY; Rose JJ; Hakim FT; Felizardo TC; Cheng AV; Robey PG; Stroncek DE; Sabatino M; Battiwalla M; Ito S; Fowler DH; Barrett AJ. 2015. Bone marrow-derived mesenchymal stromal cells harness purinergenic signaling to tolerize human Th1 cells in vivo.. In: . . MGI: J:224046
Andre MC; Erbacher A; Gille C; Schmauke V; Goecke B; Hohberger A; Mang P; Wilhelm A; Mueller I; Herr W; Lang P; Handgretinger R; Hartwig UF. 2010. Long-term human CD34(+) stem cell-engrafted nonobese diabetic/SCID/IL-2Rgamma(null) mice show impaired CD8(+) T cell maintenance and a functional arrest of immature NK cells.. In: . . MGI: J:163262
Arpke RW; Darabi R; Mader TL; Zhang Y; Toyama A; Lonetree CL; Nash N; Lowe DA; Perlingeiro RC; Kyba M. 2013. A New Immuno- Dystrophin-Deficient Model, the NSG-Mdx Mouse, Provides Evidence for Functional Improvement Following Allogeneic Satellite Cell Transplantation.. In: . . MGI: J:199729
Ashkar AA; Black GP; Wei Q; He H; Liang L; Head JR; Croy BA. 2003. Assessment of requirements for IL-15 and IFN regulatory factors in uterine NK cell differentiation and function during pregnancy.. In: . . MGI: J:85375
Aspord C; Tramcourt L; Leloup C; Molens JP; Leccia MT; Charles J; Plumas J. 2014. Imiquimod inhibits melanoma development by promoting pDC cytotoxic functions and impeding tumor vascularization.. In: . . MGI: J:214771
Baerenwaldt A; Lux A; Danzer H; Spriewald BM; Ullrich E; Heidkamp G; Dudziak D; Nimmerjahn F. 2011. Fcgamma receptor IIB (FcgammaRIIB) maintains humoral tolerance in the human immune system in vivo.. In: . . MGI: J:180174
Baird JR; Byrne KT; Lizotte PH; Toraya-Brown S; Scarlett UK; Alexander MP; Sheen MR; Fox BA; Bzik DJ; Bosenberg M; Mullins DW; Turk MJ; Fiering S. 2013. Immune-Mediated Regression of Established B16F10 Melanoma by Intratumoral Injection of Attenuated Toxoplasma gondii Protects against Rechallenge.. In: . . MGI: J:190812
Ballas ZK; Buchta CM; Rosean TR; Heusel JW; Shey MR. 2013. Role of NK cell subsets in organ-specific murine melanoma metastasis.. In: . . MGI: J:204234
Barclay SL; Yang Y; Zhang S; Fong R; Barraza A; Nolta JA; Torbett BE; Abedi M; Bauer G; Anderson JS. 2015. Safety and efficacy of a tCD25 preselective combination anti-HIV lentiviral vector in human hematopoietic stem and progenitor cells.. In: . . MGI: J:223977
Barroso-delJesus A; Lucena-Aguilar G; Sanchez L; Ligero G; Gutierrez-Aranda I; Menendez P. 2011. The Nodal inhibitor Lefty is negatively modulated by the microRNA miR-302 in human embryonic stem cells.. In: . . MGI: J:172780
Bayer AL; Lee JY; de la Barrera A; Surh CD; Malek TR. 2008. A function for IL-7R for CD4+CD25+Foxp3+ T regulatory cells.. In: . . MGI: J:137409
Berger A; Hoelbl-Kovacic A; Bourgeais J; Hoefling L; Warsch W; Grundschober E; Uras IZ; Menzl I; Putz EM; Hoermann G; Schuster C; Fajmann S; Leitner E; Kubicek S; Moriggl R; Gouilleux F; Sexl V. 2014. PAK-dependent STAT5 serine phosphorylation is required for BCR-ABL-induced leukemogenesis.. In: . . MGI: J:206976
Bertilaccio MT; Simonetti G; Dagklis A; Rocchi M; Rodriguez TV; Apollonio B; Mantovani A; Ponzoni M; Ghia P; Garlanda C; Caligaris-Cappio F; Muzio M. 2011. Lack of TIR8/SIGIRR triggers progression of chronic lymphocytic leukemia in mouse models.. In: . . MGI: J:174861
Bezman NA; Chakraborty T; Bender T; Lanier LL. 2011. miR-150 regulates the development of NK and iNKT cells.. In: . . MGI: J:179053
Billerbeck E; Barry WT; Mu K; Dorner M; Rice CM; Ploss A. 2011. Development of human CD4+FoxP3+ regulatory T cells in human stem cell factor-, granulocyte-macrophage colony-stimulating factor-, and interleukin-3-expressing NOD-SCID IL2R{gamma}null humanized mice.. In: . . MGI: J:170510
Billerbeck E; Horwitz JA; Labitt RN; Donovan BM; Vega K; Budell WC; Koo GC; Rice CM; Ploss A. 2013. Characterization of human antiviral adaptive immune responses during hepatotropic virus infection in HLA-transgenic human immune system mice.. In: . . MGI: J:205706
Blaisdell A; Crequer A; Columbus D; Daikoku T; Mittal K; Dey SK; Erlebacher A. 2015. Neutrophils Oppose Uterine Epithelial Carcinogenesis via Debridement of Hypoxic Tumor Cells.. In: . . MGI: J:227408
Bobbala D; Chen XL; Leblanc C; Mayhue M; Stankova J; Tanaka T; Chen YG; Ilangumaran S; Ramanathan S. 2012. Interleukin-15 plays an essential role in the pathogenesis of autoimmune diabetes in the NOD mouse.. In: . . MGI: J:191833
Boitano AE; Wang J; Romeo R; Bouchez LC; Parker AE; Sutton SE; Walker JR; Flaveny CA; Perdew GH; Denison MS; Schultz PG; Cooke MP. 2010. Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells.. In: . . MGI: J:167433
Borel F; Tang Q; Gernoux G; Greer C; Wang Z; Barzel A; Kay MA; Schultz LD; Greiner DL; Flotte TR; Brehm MA; Mueller C. 2017. Survival advantage of both human hepatocyte xenografts and genome editedhepatocytes for treatment of alpha-1 antitrypsin deficiency. In: . . MGI: J:243726
Bournazos S; Klein F; Pietzsch J; Seaman MS; Nussenzweig MC; Ravetch JV. 2014. Broadly neutralizing anti-HIV-1 antibodies require Fc effector functions for in vivo activity.. In: . . MGI: J:214949
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Brehm MA; Racki WJ; Leif J; Burzenski L; Hosur V; Wetmore A; Gott B; Herlihy M; Ignotz R; Dunn R; Shultz LD; Greiner DL. 2012. Engraftment of human HSC in non-irradiated newborn NOD-scid IL2rgammanull mice is enhanced by transgenic expression of membrane-bound human SCF.. In: . . MGI: J:180273
Brickshawana A; Shapiro VS; Kita H; Pease LR. 2011. Lineage(-)Sca1+c-Kit(-)CD25+ cells are IL-33-responsive type 2 innate cells in the mouse bone marrow.. In: . . MGI: J:179700
Bruedigam C; Bagger FO; Heidel FH; Paine Kuhn C; Guignes S; Song A; Austin R; Vu T; Lee E; Riyat S; Moore AS; Lock RB; Bullinger L; Hill GR; Armstrong SA; Williams DA; Lane SW. 2014. Telomerase inhibition effectively targets mouse and human AML stem cells and delays relapse following chemotherapy.. In: . . MGI: J:223853
Bryce PJ; Falahati R; Kenney LL; Leung J; Bebbington C; Tomasevic N; Krier RA; Hsu CL; Shultz LD; Greiner DL; Brehm MA. 2016. Humanized mouse model of mast cell-mediated passive cutaneous anaphylaxis and passive systemic anaphylaxis.. In: . . MGI: J:231799
Bucher C; Koch L; Vogtenhuber C; Goren E; Munger M; Panoskaltsis-Mortari A; Sivakumar P; Blazar BR. 2009. IL-21 blockade reduces graft-versus-host disease mortality by supporting inducible T regulatory cell generation.. In: . . MGI: J:155701
Bueno C; Lopes LF; Greaves M; Menendez P. 2007. Toward development of a novel NOD/SCID-based in vivo strategy to model multiple myeloma pathogenesis.. In: . . MGI: J:126691
Bugl S; Wirths S; Radsak MP; Schild H; Stein P; Andre MC; Muller MR; Malenke E; Wiesner T; Marklin M; Frick JS; Handgretinger R; Rammensee HG; Kanz L; Kopp HG. 2013. Steady-state neutrophil homeostasis is dependent on TLR4/TRIF signaling.. In: . . MGI: J:194620
Bunker JJ; Flynn TM; Koval JC; Shaw DG; Meisel M; McDonald BD; Ishizuka IE; Dent AL; Wilson PC; Jabri B; Antonopoulos DA; Bendelac A. 2015. Innate and Adaptive Humoral Responses Coat Distinct Commensal Bacteria with Immunoglobulin A.. In: . . MGI: J:233653
Burchill MA; Yang J; Vogtenhuber C; Blazar BR; Farrar MA. 2007. IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells.. In: . . MGI: J:141932
Cao X; Shores EW; Hu-Li J; Anver MR; Kelsall BL; Russell SM; Drago J; Noguchi M; Grinberg A; Bloom ET; Paul WE; Katz SI; Love PE; Leonard WJ. 1995. Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain.. In: . . MGI: J:24117
Castiglioni A; Corna G; Rigamonti E; Basso V; Vezzoli M; Monno A; Almada AE; Mondino A; Wagers AJ; Manfredi AA; Rovere-Querini P. 2015. FOXP3+ T Cells Recruited to Sites of Sterile Skeletal Muscle Injury Regulate the Fate of Satellite Cells and Guide Effective Tissue Regeneration.. In: . . MGI: J:237716
Chakraborty P; Buaas FW; Sharma M; Snyder E; de Rooij DG; Braun RE. 2014. LIN28A marks the spermatogonial progenitor population and regulates its cyclic expansion.. In: . . MGI: J:210438
Chappaz S; Finke D. 2010. The IL-7 signaling pathway regulates lymph node development independent of peripheral lymphocytes.. In: . . MGI: J:160069
Chen D; Pacal M; Wenzel P; Knoepfler PS; Leone G; Bremner R. 2009. Division and apoptosis of E2f-deficient retinal progenitors.. In: . . MGI: J:155800
Chen Q; Amaladoss A; Ye W; Liu M; Dummler S; Kong F; Wong LH; Loo HL; Loh E; Tan SQ; Tan TC; Chang KT; Dao M; Suresh S; Preiser PR; Chen J. 2014. Human natural killer cells control Plasmodium falciparum infection by eliminating infected red blood cells.. In: . . MGI: J:206650
Cheng G; Yu A; Dee MJ; Malek TR. 2013. IL-2R Signaling Is Essential for Functional Maturation of Regulatory T Cells during Thymic Development.. In: . . MGI: J:193324
Cheng M; Charoudeh HN; Brodin P; Tang Y; Lakshmikanth T; Hoglund P; Jacobsen SE; Sitnicka E. 2009. Distinct and overlapping patterns of cytokine regulation of thymic and bone marrow-derived NK cell development.. In: . . MGI: J:144325
Cheung KJ; Padmanaban V; Silvestri V; Schipper K; Cohen JD; Fairchild AN; Gorin MA; Verdone JE; Pienta KJ; Bader JS; Ewald AJ. 2016. Polyclonal breast cancer metastases arise from collective dissemination of keratin 14-expressing tumor cell clusters.. In: . . MGI: J:230438
Chiu IM; Heesters BA; Ghasemlou N; Von Hehn CA; Zhao F; Tran J; Wainger B; Strominger A; Muralidharan S; Horswill AR; Bubeck Wardenburg J; Hwang SW; Carroll MC; Woolf CJ. 2013. Bacteria activate sensory neurons that modulate pain and inflammation.. In: . . MGI: J:205431
Choi B; Chun E; Kim M; Kim SY; Kim ST; Yoon K; Lee KY; Kim SJ. 2011. Human T cell development in the liver of humanized NOD/SCID/IL-2Rgamma(null)(NSG) mice generated by intrahepatic injection of CD34(+) human (h) cord blood (CB) cells.. In: . . MGI: J:173961
Choi S; Chen Z; Tang LH; Fang Y; Shin SJ; Panarelli NC; Chen YT; Li Y; Jiang X; Du YC. 2016. Bcl-xL promotes metastasis independent of its anti-apoptotic activity.. In: . . MGI: J:235886
Civenni G; Walter A; Kobert N; Mihic-Probst D; Zipser M; Belloni B; Seifert B; Moch H; Dummer R; van den Broek M; Sommer L. 2011. Human CD271-Positive Melanoma Stem Cells Associated with Metastasis Establish Tumor Heterogeneity and Long-term Growth.. In: . . MGI: J:170990
Clark CA; Gupta HB; Sareddy G; Pandeswara S; Lao S; Yuan B; Drerup JM; Padron A; Conejo-Garcia J; Murthy K; Liu Y; Turk MJ; Thedieck K; Hurez V; Li R; Vadlamudi R; Curiel TJ. 2016. Tumor-Intrinsic PD-L1 Signals Regulate Cell Growth, Pathogenesis, and Autophagy in Ovarian Cancer and Melanoma.. In: . . MGI: J:237848
Clemente-Casares X; Blanco J; Ambalavanan P; Yamanouchi J; Singha S; Fandos C; Tsai S; Wang J; Garabatos N; Izquierdo C; Agrawal S; Keough MB; Yong VW; James E; Moore A; Yang Y; Stratmann T; Serra P; Santamaria P. 2016. Expanding antigen-specific regulatory networks to treat autoimmunity.. In: . . MGI: J:229667
Cleveland SM; Smith S; Tripathi R; Mathias EM; Goodings C; Elliott N; Peng D; El-Rifai W; Yi D; Chen X; Li L; Mullighan C; Downing JR; Love P; Dave UP. 2013. Lmo2 induces hematopoietic stem cell-like features in T-cell progenitor cells prior to leukemia.. In: . . MGI: J:196312
Constantinides MG; Gudjonson H; McDonald BD; Ishizuka IE; Verhoef PA; Dinner AR; Bendelac A. 2015. PLZF expression maps the early stages of ILC1 lineage development.. In: . . MGI: J:220811
Constantinides MG; McDonald BD; Verhoef PA; Bendelac A. 2014. A committed precursor to innate lymphoid cells.. In: . . MGI: J:205609
Cooper AB; Sawai CM; Sicinska E; Powers SE; Sicinski P; Clark MR; Aifantis I. 2006. A unique function for cyclin D3 in early B cell development.. In: . . MGI: J:112393
Cosgun KN; Rahmig S; Mende N; Reinke S; Hauber I; Schafer C; Petzold A; Weisbach H; Heidkamp G; Purbojo A; Cesnjevar R; Platz A; Bornhauser M; Schmitz M; Dudziak D; Hauber J; Kirberg J; Waskow C. 2014. Kit regulates HSC engraftment across the human-mouse species barrier.. In: . . MGI: J:232320
Covassin L; Jangalwe S; Jouvet N; Laning J; Burzenski L; Shultz LD; Brehm MA. 2013. Human immune system development and survival of NOD-scid IL2rgamma (NSG) mice engrafted with human thymus and autologous hematopoietic stem cells.. In: . . MGI: J:200896
Covassin L; Laning J; Abdi R; Langevin DL; Phillips NE; Shultz LD; Brehm MA. 2011. Human peripheral blood CD4 T cell-engrafted non-obese diabetic-scid IL2rgamma(null) H2-Ab1 (tm1Gru) Tg (human leucocyte antigen D-related 4) mice: a mouse model of human allogeneic graft-versus-host disease.. In: . . MGI: J:177904
Crow AR; Song S; Semple JW; Freedman J; Lazarus AH. 2007. A role for IL-1 receptor antagonist or other cytokines in the acute therapeutic effects of IVIg?. In: . . MGI: J:142178
Czuczman NM; Barth MJ; Gu J; Neppalli V; Mavis C; Frys SE; Hu Q; Liu S; Klener P; Vockova P; Czuczman MS; Hernandez-Ilizaliturri FJ. 2016. Pevonedistat, a NEDD8-activating enzyme inhibitor, is active in mantle cell lymphoma and enhances rituximab activity in vivo.. In: . . MGI: J:232593
D'Aveni M; Rossignol J; Coman T; Sivakumaran S; Henderson S; Manzo T; Santos e Sousa P; Bruneau J; Fouquet G; Zavala F; Alegria-Prevot O; Garfa-Traore M; Suarez F; Trebeden-Negre H; Mohty M; Bennett CL; Chakraverty R; Hermine O; Rubio MT. 2015. G-CSF mobilizes CD34+ regulatory monocytes that inhibit graft-versus-host disease.. In: . . MGI: J:234081
Dai C; Kayton NS; Shostak A; Poffenberger G; Cyphert HA; Aramandla R; Thompson C; Papagiannis IG; Emfinger C; Shiota M; Stafford JM; Greiner DL; Herrera PL; Shultz LD; Stein R; Powers AC. 2016. Stress-impaired transcription factor expression and insulin secretion in transplanted human islets.. In: . . MGI: J:234937
Danner R; Chaudhari SN; Rosenberger J; Surls J; Richie TL; Brumeanu TD; Casares S. 2011. Expression of HLA Class II Molecules in Humanized NOD.Rag1KO.IL2RgcKO Mice Is Critical for Development and Function of Human T and B Cells.. In: . . MGI: J:172588
Darabi R; Gehlbach K; Bachoo RM; Kamath S; Osawa M; Kamm KE; Kyba M; Perlingeiro RC. 2008. Functional skeletal muscle regeneration from differentiating embryonic stem cells.. In: . . MGI: J:133565
Das R; Bassiri H; Guan P; Wiener S; Banerjee PP; Zhong MC; Veillette A; Orange JS; Nichols KE. 2013. The adaptor molecule SAP plays essential roles during invariant NKT cell cytotoxicity and lytic synapse formation.. In: . . MGI: J:196692
Davies E; Reid S; Medina MF; Lichty B; Ashkar AA. 2010. IL-15 has innate anti-tumor activity independent of NK and CD8 T cells.. In: . . MGI: J:164922
Dos Santos C; McDonald T; Ho YW; Liu H; Lin A; Forman SJ; Kuo YH; Bhatia R. 2013. The Src and c-Kit kinase inhibitor dasatinib enhances p53-mediated targeting of human acute myeloid leukemia stem cells by chemotherapeutic agents.. In: . . MGI: J:202360
Dreyer AM; Matile H; Papastogiannidis P; Kamber J; Favuzza P; Voss TS; Wittlin S; Pluschke G. 2012. Passive immunoprotection of Plasmodium falciparum-infected mice designates the CyRPA as candidate malaria vaccine antigen.. In: . . MGI: J:188965
Duerr CU; McCarthy CD; Mindt BC; Rubio M; Meli AP; Pothlichet J; Eva MM; Gauchat JF; Qureshi ST; Mazer BD; Mossman KL; Malo D; Gamero AM; Vidal SM; King IL; Sarfati M; Fritz JH. 2016. Type I interferon restricts type 2 immunopathology through the regulation of group 2 innate lymphoid cells.. In: . . MGI: J:234573
Dumont N; Boyer L; Emond H; Celebi-Saltik B; Pasha R; Bazin R; Mantovani D; Roy DC; Pineault N. 2014. Medium conditioned with mesenchymal stromal cell-derived osteoblasts improves the expansion and engraftment properties of cord blood progenitors.. In: . . MGI: J:214003
Eidenschenk C; Crozat K; Krebs P; Arens R; Popkin D; Arnold CN; Blasius AL; Benedict CA; Moresco EM; Xia Y; Beutler B. 2010. Flt3 permits survival during infection by rendering dendritic cells competent to activate NK cells.. In: . . MGI: J:159599
Eisenring M; vom Berg J; Kristiansen G; Saller E; Becher B. 2010. IL-12 initiates tumor rejection via lymphoid tissue-inducer cells bearing the natural cytotoxicity receptor NKp46.. In: . . MGI: J:166535
El Haddad N; Heathcote D; Moore R; Yang S; Azzi J; Mfarrej B; Atkinson M; Sayegh MH; Lee JS; Ashton-Rickardt PG; Abdi R. 2011. Mesenchymal stem cells express serine protease inhibitor to evade the host immune response.. In: . . MGI: J:168605
Elsegeiny W; Eddens T; Chen K; Kolls JK. 2015. Anti-CD20 antibody therapy and susceptibility to Pneumocystis pneumonia.. In: . . MGI: J:229720
Endig J; Buitrago-Molina LE; Marhenke S; Reisinger F; Saborowski A; Schutt J; Limbourg F; Konecke C; Schreder A; Michael A; Misslitz AC; Healy ME; Geffers R; Clavel T; Haller D; Unger K; Finegold M; Weber A; Manns MP; Longerich T; Heikenwalder M; Vogel A. 2016. Dual Role of the Adaptive Immune System in Liver Injury and Hepatocellular Carcinoma Development.. In: . . MGI: J:234911
Enquist IB; Good Z; Jubb AM; Fuh G; Wang X; Junttila MR; Jackson EL; Leong KG. 2014. Lymph node-independent liver metastasis in a model of metastatic colorectal cancer.. In: . . MGI: J:210473
Fang R; Ismail N; Walker DH. 2012. Contribution of NK cells to the innate phase of host protection against an intracellular bacterium targeting systemic endothelium.. In: . . MGI: J:185539
Farr AR; Wu W; Choi B; Cavalcoli JD; Laouar Y. 2014. CD1d-unrestricted NKT cells are endowed with a hybrid function far superior than that of iNKT cells.. In: . . MGI: J:216401
Fattahi F; Steinbeck JA; Kriks S; Tchieu J; Zimmer B; Kishinevsky S; Zeltner N; Mica Y; El-Nachef W; Zhao H; de Stanchina E; Gershon MD; Grikscheit TC; Chen S; Studer L. 2016. Deriving human ENS lineages for cell therapy and drug discovery in Hirschsprung disease.. In: . . MGI: J:229669
Feng CG; Kaviratne M; Rothfuchs AG; Cheever A; Hieny S; Young HA; Wynn TA; Sher A. 2006. NK cell-derived IFN-gamma differentially regulates innate resistance and neutrophil response in T cell-deficient hosts infected with Mycobacterium tuberculosis.. In: . . MGI: J:140483
Feng M; Chen JY; Weissman-Tsukamoto R; Volkmer JP; Ho PY; McKenna KM; Cheshier S; Zhang M; Guo N; Gip P; Mitra SS; Weissman IL. 2015. Macrophages eat cancer cells using their own calreticulin as a guide: roles of TLR and Btk.. In: . . MGI: J:220007
Fiorini E; Ferrero I; Merck E; Favre S; Pierres M; Luther SA; MacDonald HR. 2008. Cutting edge: thymic crosstalk regulates delta-like 4 expression on cortical epithelial cells.. In: . . MGI: J:142081
Flesken-Nikitin A; Hwang CI; Cheng CY; Michurina TV; Enikolopov G; Nikitin AY. 2013. Ovarian surface epithelium at the junction area contains a cancer-prone stem cell niche.. In: . . MGI: J:194916
Font-Burgada J; Shalapour S; Ramaswamy S; Hsueh B; Rossell D; Umemura A; Taniguchi K; Nakagawa H; Valasek MA; Ye L; Kopp JL; Sander M; Carter H; Deisseroth K; Verma IM; Karin M. 2015. Hybrid Periportal Hepatocytes Regenerate the Injured Liver without Giving Rise to Cancer.. In: . . MGI: J:224826
Fontenot JD; Rasmussen JP; Gavin MA; Rudensky AY. 2005. A function for interleukin 2 in Foxp3-expressing regulatory T cells.. In: . . MGI: J:112602
Friedline RH; Ko HJ; Jung DY; Lee Y; Bortell R; Dagdeviren S; Patel PR; Hu X; Inashima K; Kearns C; Tsitsilianos N; Shafiq U; Shultz LD; Lee KW; Greiner DL; Kim JK. 2016. Genetic ablation of lymphocytes and cytokine signaling in nonobese diabetic mice prevents diet-induced obesity and insulin resistance.. In: . . MGI: J:230896
Fukunaga-Kalabis M; Martinez G; Nguyen TK; Kim D; Santiago-Walker A; Roesch A; Herlyn M. 2010. Tenascin-C promotes melanoma progression by maintaining the ABCB5-positive side population.. In: . . MGI: J:166563
Gan Y; Liu Q; Wu W; Yin JX; Bai XF; Shen R; Wang Y; Chen J; La Cava A; Poursine-Laurent J; Yokoyama W; Shi FD. 2014. Ischemic neurons recruit natural killer cells that accelerate brain infarction.. In: . . MGI: J:206801
Gill N; Rosenthal KL; Ashkar AA. 2005. NK and NKT cell-independent contribution of interleukin-15 to innate protection against mucosal viral infection.. In: . . MGI: J:97038
Goldstein AS; Huang J; Guo C; Garraway IP; Witte ON. 2010. Identification of a cell of origin for human prostate cancer.. In: . . MGI: J:162606
Gomez Perdiguero E; Klapproth K; Schulz C; Busch K; Azzoni E; Crozet L; Garner H; Trouillet C; de Bruijn MF; Geissmann F; Rodewald HR. 2015. Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors.. In: . . MGI: J:219492
Gorantla S; Makarov E; Finke-Dwyer J; Gebhart CL; Domm W; Dewhurst S; Gendelman HE; Poluektova LY. 2010. CD8+ cell depletion accelerates HIV-1 immunopathology in humanized mice.. In: . . MGI: J:161304
Griffin RL; Kupper TS; Divito SJ. 2015. Humanized Mice in Dermatology Research.. In: . . MGI: J:228055
Guan J; Miah SM; Wilson ZS; Erick TK; Banh C; Brossay L. 2014. Role of type I interferon receptor signaling on NK cell development and functions.. In: . . MGI: J:222452
Guimond M; Leonard WJ; Spolski R; Rossi SW; Veenstra RG; Hollander GA; Mackall CL; Blazar BR. 2008. Thymic stromal lymphopoietin is not necessary or sufficient to mediate the thymopoietic effects of keratinocyte growth factor.. In: . . MGI: J:130979
Guimond M; Veenstra RG; Grindler DJ; Zhang H; Cui Y; Murphy RD; Kim SY; Na R; Hennighausen L; Kurtulus S; Erman B; Matzinger P; Merchant MS; Mackall CL. 2009. Interleukin 7 signaling in dendritic cells regulates the homeostatic proliferation and niche size of CD4+ T cells.. In: . . MGI: J:144504
Gundry MC; Brunetti L; Lin A; Mayle AE; Kitano A; Wagner D; Hsu JI; Hoegenauer KA; Rooney CM; Goodell MA; Nakada D. 2016. Highly Efficient Genome Editing of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9.. In: . . MGI: J:240901
Gurish MF; Tao H; Abonia JP; Arya A; Friend DS; Parker CM; Austen KF. 2001. Intestinal mast cell progenitors require CD49dbeta7 (alpha4beta7 integrin) for tissue-specific homing.. In: . . MGI: J:119138
Haddad G; Zhabyeyev P; Farhan M; Zhu LF; Kassiri Z; Rayner DC; Vanhaesebroeck B; Oudit GY; Murray AG. 2014. Phosphoinositide 3-kinase beta mediates microvascular endothelial repair of thrombotic microangiopathy.. In: . . MGI: J:214815
Haetscher N; Feuermann Y; Wingert S; Rehage M; Thalheimer FB; Weiser C; Bohnenberger H; Jung K; Schroeder T; Serve H; Oellerich T; Hennighausen L; Rieger MA. 2015. STAT5-regulated microRNA-193b controls haematopoietic stem and progenitor cell expansion by modulating cytokine receptor signalling.. In: . . MGI: J:228007
Hanks BA; Holtzhausen A; Evans KS; Jamieson R; Gimpel P; Campbell OM; Hector-Greene M; Sun L; Tewari A; George A; Starr M; Nixon A; Augustine C; Beasley G; Tyler DS; Osada T; Morse MA; Ling L; Lyerly HK; Blobe GC. 2013. Type III TGF-beta receptor downregulation generates an immunotolerant tumor microenvironment.. In: . . MGI: J:201617
Hao J; Shi FD; Abdelwahab M; Shi SX; Simard A; Whiteaker P; Lukas R; Zhou Q. 2013. Nicotinic receptor beta2 determines NK cell-dependent metastasis in a murine model of metastatic lung cancer.. In: . . MGI: J:197263
Harris WJ; Huang X; Lynch JT; Spencer GJ; Hitchin JR; Li Y; Ciceri F; Blaser JG; Greystoke BF; Jordan AM; Miller CJ; Ogilvie DJ; Somervaille TC. 2012. The histone demethylase KDM1A sustains the oncogenic potential of MLL-AF9 leukemia stem cells.. In: . . MGI: J:189339
Heaney NB; Pellicano F; Zhang B; Crawford L; Chu S; Kazmi SM; Allan EK; Jorgensen HG; Irvine AE; Bhatia R; Holyoake TL. 2010. Bortezomib induces apoptosis in primitive chronic myeloid leukemia cells including LTC-IC and NOD/SCID repopulating cells.. In: . . MGI: J:162612
Hoggatt J; Singh P; Sampath J; Pelus LM. 2009. Prostaglandin E2 enhances hematopoietic stem cell homing, survival, and proliferation.. In: . . MGI: J:148898
Holland JD; Gyorffy B; Vogel R; Eckert K; Valenti G; Fang L; Lohneis P; Elezkurtaj S; Ziebold U; Birchmeier W. 2013. Combined Wnt/beta-catenin, Met, and CXCL12/CXCR4 signals characterize basal breast cancer and predict disease outcome.. In: . . MGI: J:206839
Holopainen T; Saharinen P; D'Amico G; Lampinen A; Eklund L; Sormunen R; Anisimov A; Zarkada G; Lohela M; Helotera H; Tammela T; Benjamin LE; Yla-Herttuala S; Leow CC; Koh GY; Alitalo K. 2012. Effects of angiopoietin-2-blocking antibody on endothelial cell-cell junctions and lung metastasis.. In: . . MGI: J:184937
Holt N; Wang J; Kim K; Friedman G; Wang X; Taupin V; Crooks GM; Kohn DB; Gregory PD; Holmes MC; Cannon PM. 2010. Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo.. In: . . MGI: J:162607
Howitt MR; Lavoie S; Michaud M; Blum AM; Tran SV; Weinstock JV; Gallini CA; Redding K; Margolskee RF; Osborne LC; Artis D; Garrett WS. 2016. Tuft cells, taste-chemosensory cells, orchestrate parasite type 2 immunity in the gut.. In: . . MGI: J:231305
Hu Z; Van Rooijen N; Yang YG. 2011. Macrophages prevent human red blood cell reconstitution in immunodeficient mice.. In: . . MGI: J:178783
Hubner A; Mulholland DJ; Standen CL; Karasarides M; Cavanagh-Kyros J; Barrett T; Chi H; Greiner DL; Tournier C; Sawyers CL; Flavell RA; Wu H; Davis RJ. 2012. JNK and PTEN cooperatively control the development of invasive adenocarcinoma of the prostate.. In: . . MGI: J:186492
Imtiyaz HZ; Zhou X; Zhang H; Chen D; Hu T; Zhang J. 2009. The death domain of FADD is essential for embryogenesis, lymphocyte development, and proliferation.. In: . . MGI: J:149068
Ippolito GC; Hoi KH; Reddy ST; Carroll SM; Ge X; Rogosch T; Zemlin M; Shultz LD; Ellington AD; Vandenberg CL; Georgiou G. 2012. Antibody repertoires in humanized NOD-scid-IL2Rgamma(null) mice and human B cells reveals human-like diversification and tolerance checkpoints in the mouse.. In: . . MGI: J:187283
Ishikawa F; Yasukawa M; Lyons B; Yoshida S; Miyamoto T; Yoshimoto G; Watanabe T; Akashi K; Shultz LD; Harada M. 2005. Development of functional human blood and immune systems in NOD/SCID/IL2 receptor {gamma} chain(null) mice.. In: . . MGI: J:142411
Jahchan NS; Lim JS; Bola B; Morris K; Seitz G; Tran KQ; Xu L; Trapani F; Morrow CJ; Cristea S; Coles GL; Yang D; Vaka D; Kareta MS; George J; Mazur PK; Nguyen T; Anderson WC; Dylla SJ; Blackhall F; Peifer M; Dive C; Sage J. 2016. Identification and Targeting of Long-Term Tumor-Propagating Cells in Small Cell Lung Cancer.. In: . . MGI: J:238584
Jaiswal S; Pearson T; Friberg H; Shultz LD; Greiner DL; Rothman AL; Mathew A. 2009. Dengue virus infection and virus-specific HLA-A2 restricted immune responses in humanized NOD-scid IL2rgammanull mice.. In: . . MGI: J:154110
Janes MR; Limon JJ; So L; Chen J; Lim RJ; Chavez MA; Vu C; Lilly MB; Mallya S; Ong ST; Konopleva M; Martin MB; Ren P; Liu Y; Rommel C; Fruman DA. 2010. Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor.. In: . . MGI: J:162611
Juelke K; Killig M; Luetke-Eversloh M; Parente E; Gruen J; Morandi B; Ferlazzo G; Thiel A; Schmitt-Knosalla I; Romagnani C. 2010. CD62L expression identifies a unique subset of polyfunctional CD56dim NK cells.. In: . . MGI: J:163485
Junttila IS; Mizukami K; Dickensheets H; Meier-Schellersheim M; Yamane H; Donnelly RP; Paul WE. 2008. Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4Ralpha, IL-13Ralpha1, and gammac regulates relative cytokine sensitivity.. In: . . MGI: J:141103
Jurczyk A; Nowosielska A; Przewozniak N; Aryee KE; DiIorio P; Blodgett D; Yang C; Campbell-Thompson M; Atkinson M; Shultz L; Rittenhouse A; Harlan D; Greiner D; Bortell R. 2016. Beyond the brain: disrupted in schizophrenia 1 regulates pancreatic beta-cell function via glycogen synthase kinase-3beta.. In: . . MGI: J:230840
Kang SJ; Liang HE; Reizis B; Locksley RM. 2008. Regulation of hierarchical clustering and activation of innate immune cells by dendritic cells.. In: . . MGI: J:142395
Karst AM; Levanon K; Drapkin R. 2011. Modeling high-grade serous ovarian carcinogenesis from the fallopian tube.. In: . . MGI: J:172047
Kawahara M; Pandolfi A; Bartholdy B; Barreyro L; Will B; Roth M; Okoye-Okafor UC; Todorova TI; Figueroa ME; Melnick A; Mitsiades CS; Steidl U. 2012. H2.0-like homeobox regulates early hematopoiesis and promotes acute myeloid leukemia.. In: . . MGI: J:191823
Kelly J; Spolski R; Imada K; Bollenbacher J; Lee S; Leonard WJ. 2003. A role for stat5 in CD8(+) T cell homeostasis.. In: . . MGI: J:80897
Kim HJ; Verbinnen B; Tang X; Lu L; Cantor H. 2010. Inhibition of follicular T-helper cells by CD8(+) regulatory T cells is essential for self tolerance.. In: . . MGI: J:164663
Kim HY; Lee HJ; Chang YJ; Pichavant M; Shore SA; Fitzgerald KA; Iwakura Y; Israel E; Bolger K; Faul J; DeKruyff RH; Umetsu DT. 2014. Interleukin-17-producing innate lymphoid cells and the NLRP3 inflammasome facilitate obesity-associated airway hyperreactivity.. In: . . MGI: J:226577
Kim KD; Srikanth S; Yee MK; Mock DC; Lawson GW; Gwack Y. 2011. ORAI1 deficiency impairs activated T cell death and enhances T cell survival.. In: . . MGI: J:179333
Kim S; Dubrovska A; Salamone RJ; Walker JR; Grandinetti KB; Bonamy GM; Orth AP; Elliott J; Porta DG; Garcia-Echeverria C; Reddy VA. 2013. FGFR2 promotes breast tumorigenicity through maintenance of breast tumor-initiating cells.. In: . . MGI: J:195822
King MA; Covassin L; Brehm MA; Racki W; Pearson T; Leif J; Laning J; Fodor W; Foreman O; Burzenski L; Chase TH; Gott B; Rossini AA; Bortell R; Shultz LD; Greiner DL. 2009. Human peripheral blood leucocyte non-obese diabetic-severe combined immunodeficiency interleukin-2 receptor gamma chain gene mouse model of xenogeneic graft-versus-host-like disease and the role of host major histocompatibility complex.. In: . . MGI: J:151390
Kinkel SA; Galeev R; Flensburg C; Keniry A; Breslin K; Gilan O; Lee S; Liu J; Chen K; Gearing LJ; Moore DL; Alexander WS; Dawson M; Majewski IJ; Oshlack A; Larsson J; Blewitt ME. 2015. Jarid2 regulates hematopoietic stem cell function by acting with polycomb repressive complex 2.. In: . . MGI: J:222052
Klose CS; Kiss EA; Schwierzeck V; Ebert K; Hoyler T; d'Hargues Y; Goppert N; Croxford AL; Waisman A; Tanriver Y; Diefenbach A. 2013. A T-bet gradient controls the fate and function of CCR6-RORgammat+ innate lymphoid cells.. In: . . MGI: J:194555
Klug F; Prakash H; Huber PE; Seibel T; Bender N; Halama N; Pfirschke C; Voss RH; Timke C; Umansky L; Klapproth K; Schakel K; Garbi N; Jager D; Weitz J; Schmitz-Winnenthal H; Hammerling GJ; Beckhove P. 2013. Low-dose irradiation programs macrophage differentiation to an iNOS(+)/M1 phenotype that orchestrates effective T cell immunotherapy.. In: . . MGI: J:206743
Kobayashi M; Nakamura K; Cornforth M; Suzuki F. 2012. Role of M2b macrophages in the acceleration of bacterial translocation and subsequent sepsis in mice exposed to whole body [137Cs] gamma-irradiation.. In: . . MGI: J:188934
Krueger A; von Boehmer H. 2007. Identification of a T lineage-committed progenitor in adult blood.. In: . . MGI: J:118201
Ksander BR; Kolovou PE; Wilson BJ; Saab KR; Guo Q; Ma J; McGuire SP; Gregory MS; Vincent WJ; Perez VL; Cruz-Guilloty F; Kao WW; Call MK; Tucker BA; Zhan Q; Murphy GF; Lathrop KL; Alt C; Mortensen LJ; Lin CP; Zieske JD; Frank MH; Frank NY. 2014. ABCB5 is a limbal stem cell gene required for corneal development and repair.. In: . . MGI: J:213708
Kumar P; Ban HS; Kim SS; Wu H; Pearson T; Greiner DL; Laouar A; Yao J; Haridas V; Habiro K; Yang YG; Jeong JH; Lee KY; Kim YH; Kim SW; Peipp M; Fey GH; Manjunath N; Shultz LD; Lee SK; Shankar P. 2008. T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice.. In: . . MGI: J:142409
Kuroda-Morimoto M; Tanaka H; Hayashi N; Nakahira M; Imai Y; Imamura M; Yasuda K; Yumikura-Futatsugi S; Matsui K; Nakashima T; Sugimura K; Tsutsui H; Sano H; Nakanishi K. 2010. Contribution of IL-18 to eosinophilic airway inflammation induced by immunization and challenge with Staphylococcus aureus proteins.. In: . . MGI: J:161302
Law KM; Komarova NL; Yewdall AW; Lee RK; Herrera OL; Wodarz D; Chen BK. 2016. In Vivo HIV-1 Cell-to-Cell Transmission Promotes Multicopy Micro-compartmentalized Infection.. In: . . MGI: J:238305
Leung J; Suh WK. 2013. Host B7-H4 regulates antitumor T cell responses through inhibition of myeloid-derived suppressor cells in a 4T1 tumor transplantation model.. In: . . MGI: J:204842
Li L; Wang L; Li L; Wang Z; Ho Y; McDonald T; Holyoake TL; Chen W; Bhatia R. 2012. Activation of p53 by SIRT1 Inhibition Enhances Elimination of CML Leukemia Stem Cells in Combination with Imatinib.. In: . . MGI: J:181458
Li S; Ling C; Zhong L; Li M; Su Q; He R; Tang Q; Greiner DL; Shultz LD; Brehm MA; Flotte TR; Mueller C; Srivastava A; Gao G. 2015. Efficient and Targeted Transduction of Nonhuman Primate Liver With Systemically Delivered Optimized AAV3B Vectors.. In: . . MGI: J:230567
Libby SJ; Brehm MA; Greiner DL; Shultz LD; McClelland M; Smith KD; Cookson BT; Karlinsey JE; Kinkel TL; Porwollik S; Canals R; Cummings LA; Fang FC. 2010. Humanized nonobese diabetic-scid IL2rgammanull mice are susceptible to lethal Salmonella Typhi infection.. In: . . MGI: J:163745
Liu Q; Sanai N; Jin WN; La Cava A; Van Kaer L; Shi FD. 2016. Neural stem cells sustain natural killer cells that dictate recovery from brain inflammation.. In: . . MGI: J:234432
Liu R; Liu C; Chen D; Yang WH; Liu X; Liu CG; Dugas CM; Tang F; Zheng P; Liu Y; Wang L. 2015. FOXP3 Controls an miR-146/NF-kappaB Negative Feedback Loop That Inhibits Apoptosis in Breast Cancer Cells.. In: . . MGI: J:220159
Long AH; Haso WM; Shern JF; Wanhainen KM; Murgai M; Ingaramo M; Smith JP; Walker AJ; Kohler ME; Venkateshwara VR; Kaplan RN; Patterson GH; Fry TJ; Orentas RJ; Mackall CL. 2015. 4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors.. In: . . MGI: J:228468
Long BR; Stoddart CA. 2012. Alpha Interferon and HIV Infection Cause Activation of Human T Cells in NSG-BLT Mice.. In: . . MGI: J:181199
Lu L; Ikizawa K; Hu D; Werneck MB; Wucherpfennig KW; Cantor H. 2007. Regulation of activated CD4+ T cells by NK cells via the Qa-1-NKG2A inhibitory pathway.. In: . . MGI: J:123555
Lu M; Kardel MD; O'Connor MD; Eaves CJ. 2009. Enhanced generation of hematopoietic cells from human hepatocarcinoma cell-stimulated human embryonic and induced pluripotent stem cells.. In: . . MGI: J:151435
Ma S; Shukla V; Fang L; Gould KA; Joshi SS; Lu R. 2013. Accelerated development of chronic lymphocytic leukemia in New Zealand Black mice expressing a low level of interferon regulatory factor 4.. In: . . MGI: J:203533
Ma S; Turetsky A; Trinh L; Lu R. 2006. IFN regulatory factor 4 and 8 promote Ig light chain kappa locus activation in pre-B cell development.. In: . . MGI: J:140693
Madera S; Rapp M; Firth MA; Beilke JN; Lanier LL; Sun JC. 2016. Type I IFN promotes NK cell expansion during viral infection by protecting NK cells against fratricide.. In: . . MGI: J:232648
Madlambayan GJ; Meacham AM; Hosaka K; Mir S; Jorgensen M; Scott EW; Siemann DW; Cogle CR. 2010. Leukemia regression by vascular disruption and antiangiogenic therapy.. In: . . MGI: J:164541
Mahapatro M; Foersch S; Hefele M; He GW; Giner-Ventura E; Mchedlidze T; Kindermann M; Vetrano S; Danese S; Gunther C; Neurath MF; Wirtz S; Becker C. 2016. Programming of Intestinal Epithelial Differentiation by IL-33 Derived from Pericryptal Fibroblasts in Response to Systemic Infection.. In: . . MGI: J:235754
Majeti R; Park CY; Weissman IL. 2007. Identification of a hierarchy of multipotent hematopoietic progenitors in human cord blood.. In: . . MGI: J:142413
Majewska-Szczepanik M; Paust S; von Andrian UH; Askenase PW; Szczepanik M. 2013. Natural killer cell-mediated contact sensitivity develops rapidly and depends on interferon-alpha, interferon-gamma and interleukin-12.. In: . . MGI: J:202643
Marsden MD; Kovochich M; Suree N; Shimizu S; Mehta R; Cortado R; Bristol G; An DS; Zack JA. 2012. HIV Latency in the Humanized BLT Mouse.. In: . . MGI: J:179389
Marsh SE; Abud EM; Lakatos A; Karimzadeh A; Yeung ST; Davtyan H; Fote GM; Lau L; Weinger JG; Lane TE; Inlay MA; Poon WW; Blurton-Jones M. 2016. The adaptive immune system restrains Alzheimer's disease pathogenesis by modulating microglial function.. In: . . MGI: J:231007
Martinez-Forero I; Azpilikueta A; Bolanos-Mateo E; Nistal-Villan E; Palazon A; Teijeira A; Perez-Chacon G; Morales-Kastresana A; Murillo O; Jure-Kunkel M; Zapata JM; Melero I. 2013. T cell costimulation with anti-CD137 monoclonal antibodies is mediated by K63-polyubiquitin-dependent signals from endosomes.. In: . . MGI: J:204832
Martins VC; Busch K; Juraeva D; Blum C; Ludwig C; Rasche V; Lasitschka F; Mastitsky SE; Brors B; Hielscher T; Fehling HJ; Rodewald HR. 2014. Cell competition is a tumour suppressor mechanism in the thymus.. In: . . MGI: J:210588
Martins VC; Ruggiero E; Schlenner SM; Madan V; Schmidt M; Fink PJ; von Kalle C; Rodewald HR. 2012. Thymus-autonomous T cell development in the absence of progenitor import.. In: . . MGI: J:189166
Masse GX; Corcuff E; Decaluwe H; Bommhardt U; Lantz O; Buer J; Di Santo JP. 2007. gamma(c) cytokines provide multiple homeostatic signals to naive CD4(+) T cells.. In: . . MGI: J:124346
Maykel J; Liu JH; Li H; Shultz LD; Greiner DL; Houghton J. 2014. NOD-scidIl2rg (tm1Wjl) and NOD-Rag1 (null) Il2rg (tm1Wjl) : a model for stromal cell-tumor cell interaction for human colon cancer.. In: . . MGI: J:227975
McCaughtry TM; Etzensperger R; Alag A; Tai X; Kurtulus S; Park JH; Grinberg A; Love P; Feigenbaum L; Erman B; Singer A. 2012. Conditional deletion of cytokine receptor chains reveals that IL-7 and IL-15 specify CD8 cytotoxic lineage fate in the thymus.. In: . . MGI: J:190889
McDermott SP; Eppert K; Lechman ER; Doedens M; Dick JE. 2010. Comparison of human cord blood engraftment between immunocompromised mouse strains.. In: . . MGI: J:162809
McIntosh BE; Brown ME; Duffin BM; Maufort JP; Vereide DT; Slukvin II; Thomson JA. 2015. Nonirradiated NOD,B6.SCID Il2rgamma(-/-)Kit(W41/W41) (NBSGW) Mice Support Multilineage Engraftment of Human Hematopoietic Cells.. In: . . MGI: J:218738
Merck E; Voyle RB; MacDonald HR. 2009. Ly49D engagement on T lymphocytes induces TCR-independent activation and CD8 effector functions that control tumor growth.. In: . . MGI: J:143041
Min-Oo G; Bezman NA; Madera S; Sun JC; Lanier LL. 2014. Proapoptotic Bim regulates antigen-specific NK cell contraction and the generation of the memory NK cell pool after cytomegalovirus infection.. In: . . MGI: J:214519
Mintern JD; Maurice MM; Ploegh HL; Schott E. 2004. Thymic selection and peripheral activation of CD8 T cells by the same class I MHC/peptide complex.. In: . . MGI: J:87075
Moro K; Yamada T; Tanabe M; Takeuchi T; Ikawa T; Kawamoto H; Furusawa J; Ohtani M; Fujii H; Koyasu S. 2010. Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells.. In: . . MGI: J:156764
Morris SC; Orekhova T; Meadows MJ; Heidorn SM; Yang J; Finkelman FD. 2006. IL-4 induces in vivo production of IFN-gamma by NK and NKT cells.. In: . . MGI: J:131660
Mota J; Rico-Hesse R. 2009. Humanized mice show clinical signs of dengue fever according to infecting virus genotype.. In: . . MGI: J:153922
Mukai K; Matsuoka K; Taya C; Suzuki H; Yokozeki H; Nishioka K; Hirokawa K; Etori M; Yamashita M; Kubota T; Minegishi Y; Yonekawa H; Karasuyama H. 2005. Basophils play a critical role in the development of IgE-mediated chronic allergic inflammation independently of T cells and mast cells.. In: . . MGI: J:100537
Mustafi R; Dougherty U; Shah H; Dehghan H; Gliksberg A; Wu J; Zhu H; Joseph L; Hart J; Dive C; Fichera A; Threadgill D; Bissonnette M. 2012. Both stromal cell and colonocyte epidermal growth factor receptors control HCT116 colon cancer cell growth in tumor xenografts.. In: . . MGI: J:192954
Nakajima H; Leonard WJ. 1997. Impaired peripheral deletion of activated T cells in mice lacking the common cytokine receptor gamma-chain: defective Fas ligand expression in gamma-chain-deficient mice.. In: . . MGI: J:43962
Nakajima H; Leonard WJ. 1999. Role of Bcl-2 in alpha beta T cell development in mice deficient in the common cytokine receptor gamma-chain: the requirement for Bcl-2 differs depending on the TCR/MHC affinity.. In: . . MGI: J:52019
Nakajima H; Shores EW; Noguchi M; Leonard WJ. 1997. The common cytokine receptor gamma chain plays an essential role in regulating lymphoid homeostasis.. In: . . MGI: J:107159
Naramura M; Nandwani N; Gu H; Band V; Band H. 2010. Rapidly fatal myeloproliferative disorders in mice with deletion of Casitas B-cell lymphoma (Cbl) and Cbl-b in hematopoietic stem cells.. In: . . MGI: J:164365
Nolte T; Zadeh-Khorasani M; Safarov O; Rueff F; Varga R; Herbach N; Wanke R; Wollenberg A; Mueller T; Gropp R; Wolf E; Siebeck M. 2013. Induction of oxazolone-mediated features of atopic dermatitis in NOD-scid IL2Rgamma(null) mice engrafted with human peripheral blood mononuclear cells.. In: . . MGI: J:192789
Nozad Charoudeh H; Tang Y; Cheng M; Cilio CM; Jacobsen SE; Sitnicka E. 2010. Identification of an NK/T cell-restricted progenitor in adult bone marrow contributing to bone marrow- and thymic-dependent NK cells.. In: . . MGI: J:162802
Nucera S; Giustacchini A; Boccalatte F; Calabria A; Fanciullo C; Plati T; Ranghetti A; Garcia-Manteiga J; Cittaro D; Benedicenti F; Lechman ER; Dick JE; Ponzoni M; Ciceri F; Montini E; Gentner B; Naldini L. 2016. miRNA-126 Orchestrates an Oncogenic Program in B Cell Precursor Acute Lymphoblastic Leukemia.. In: . . MGI: J:232327
O'Boyle G; Fox CR; Walden HR; Willet JD; Mavin ER; Hine DW; Palmer JM; Barker CE; Lamb CA; Ali S; Kirby JA. 2012. Chemokine receptor CXCR3 agonist prevents human T-cell migration in a humanized model of arthritic inflammation.. In: . . MGI: J:182231
O'Leary JG; Goodarzi M; Drayton DL; von Andrian UH. 2006. T cell- and B cell-independent adaptive immunity mediated by natural killer cells.. In: . . MGI: J:112596
O'Sullivan T; Saddawi-Konefka R; Vermi W; Koebel CM; Arthur C; White JM; Uppaluri R; Andrews DM; Ngiow SF; Teng MW; Smyth MJ; Schreiber RD; Bui JD. 2012. Cancer immunoediting by the innate immune system in the absence of adaptive immunity.. In: . . MGI: J:192935
Oberbarnscheidt MH; Zeng Q; Li Q; Dai H; Williams AL; Shlomchik WD; Rothstein DM; Lakkis FG. 2014. Non-self recognition by monocytes initiates allograft rejection.. In: . . MGI: J:213858
Ohteki T; Suzue K; Maki C; Ota T; Koyasu S. 2001. Critical role of IL-15-IL-15R for antigen-presenting cell functions in the innate immune response.. In: . . MGI: J:125660
Origanti S; Cai SR; Munir AZ; White LS; Piwnica-Worms H. 2013. Synthetic lethality of Chk1 inhibition combined with p53 and/or p21 loss during a DNA damage response in normal and tumor cells.. In: . . MGI: J:193369
Orr SJ; Roessler S; Quigley L; Chan T; Ford JW; O'Connor GM; McVicar DW. 2010. Implications for gene therapy-limiting expression of IL-2Rgammac delineate differences in signaling thresholds required for lymphocyte development and maintenance.. In: . . MGI: J:162459
Oruganti SR; Torres DJ; Krebsbach S; Asperti-Boursin F; Winters J; Matlawska-Wasowska K; Winter SS; Halsey C; Cannon JL. 2017. CARMA1 is a novel regulator of T-ALL disease and leukemic cell migration to the CNS.. In: . . MGI: J:237842
Ozaki H; Mori K; Nakagawa Y; Hoshikawa S; Ito S; Inoue Y; Takai T; Yoshida K. 2009. Autoimmune thyroiditis in Fcgamma receptor-deficient nonobese diabetic mice.. In: . . MGI: J:151452
Ozturk F; Li Y; Zhu X; Guda C; Nawshad A. 2013. Systematic analysis of palatal transcriptome to identify cleft palate genes within TGFbeta3-knockout mice alleles: RNA-Seq analysis of TGFbeta3 Mice.. In: . . MGI: J:196701
Park H; Tsang M; Iritani BM; Bevan MJ. 2014. Metabolic regulator Fnip1 is crucial for iNKT lymphocyte development.. In: . . MGI: J:211065
Pathania R; Ramachandran S; Elangovan S; Padia R; Yang P; Cinghu S; Veeranan-Karmegam R; Arjunan P; Gnana-Prakasam JP; Sadanand F; Pei L; Chang CS; Choi JH; Shi H; Manicassamy S; Prasad PD; Sharma S; Ganapathy V; Jothi R; Thangaraju M. 2015. DNMT1 is essential for mammary and cancer stem cell maintenance and tumorigenesis.. In: . . MGI: J:222799
Pathania R; Ramachandran S; Mariappan G; Thakur P; Shi H; Choi JH; Manicassamy S; Kolhe R; Prasad PD; Sharma S; Lokeshwar BL; Ganapathy V; Thangaraju M. 2016. Combined Inhibition of DNMT and HDAC Blocks the Tumorigenicity of Cancer Stem-like Cells and Attenuates Mammary Tumor Growth.. In: . . MGI: J:232034
Paust S; Gill HS; Wang BZ; Flynn MP; Moseman EA; Senman B; Szczepanik M; Telenti A; Askenase PW; Compans RW; von Andrian UH. 2010. Critical role for the chemokine receptor CXCR6 in NK cell-mediated antigen-specific memory of haptens and viruses.. In: . . MGI: J:167327
Pearson T; Greiner DL; Shultz LD. 2008. Creation of 'humanized' mice to study human immunity.. In: . . MGI: J:151386
Pearson T; Shultz LD; Lief J; Burzenski L; Gott B; Chase T; Foreman O; Rossini AA; Bottino R; Trucco M; Greiner DL. 2008. A new immunodeficient hyperglycaemic mouse model based on the Ins2 ( Akita ) mutation for analyses of human islet and beta stem and progenitor cell function.. In: . . MGI: J:138005
Pearson T; Shultz LD; Miller D; King M; Laning J; Fodor W; Cuthbert A; Burzenski L; Gott B; Lyons B; Foreman O; Rossini AA; Greiner DL. 2008. Non-obese diabetic-recombination activating gene-1 (NOD-Rag1 null) interleukin (IL)-2 receptor common gamma chain (IL2r gamma null) null mice: a radioresistant model for human lymphohaematopoietic engraftment.. In: . . MGI: J:140388
Pei Y; Moore CE; Wang J; Tewari AK; Eroshkin A; Cho YJ; Witt H; Korshunov A; Read TA; Sun JL; Schmitt EM; Miller CR; Buckley AF; McLendon RE; Westbrook TF; Northcott PA; Taylor MD; Pfister SM; Febbo PG; Wechsler-Reya RJ. 2012. An Animal Model of MYC-Driven Medulloblastoma.. In: . . MGI: J:181463
Perol L; Lindner JM; Caudana P; Nunez NG; Baeyens A; Valle A; Sedlik C; Loirat D; Boyer O; Creange A; Cohen JL; Rogner UC; Yamanouchi J; Marchant M; Leber XC; Scharenberg M; Gagnerault MC; Mallone R; Battaglia M; Santamaria P; Hartemann A; Traggiai E; Piaggio E. 2016. Loss of immune tolerance to IL-2 in type 1 diabetes.. In: . . MGI: J:242356
Porcellini S; Traggiai E; Schenk U; Ferrera D; Matteoli M; Lanzavecchia A; Michalak M; Grassi F. 2006. Regulation of peripheral T cell activation by calreticulin.. In: . . MGI: J:119147
Porter BO; Malek TR. 1999. IL-2Rbeta/IL-7Ralpha doubly deficient mice recapitulate the thymic and intraepithelial lymphocyte (IEL) developmental defects of gammac-/- mice: roles for both IL-2 and IL-15 in CD8alphaalpha IEL development.. In: . . MGI: J:58655
Price AE; Liang HE; Sullivan BM; Reinhardt RL; Eisley CJ; Erle DJ; Locksley RM. 2010. Systemically dispersed innate IL-13-expressing cells in type 2 immunity.. In: . . MGI: J:161387
Purwana I; Zheng J; Li X; Deurloo M; Son DO; Zhang Z; Liang C; Shen E; Tadkase A; Feng ZP; Li Y; Hasilo C; Paraskevas S; Bortell R; Greiner DL; Atkinson M; Prud'homme GJ; Wang Q. 2014. GABA promotes human beta-cell proliferation and modulates glucose homeostasis.. In: . . MGI: J:230144
Putz EM; Gotthardt D; Hoermann G; Csiszar A; Wirth S; Berger A; Straka E; Rigler D; Wallner B; Jamieson AM; Pickl WF; Zebedin-Brandl EM; Muller M; Decker T; Sexl V. 2013. CDK8-mediated STAT1-S727 phosphorylation restrains NK cell cytotoxicity and tumor surveillance.. In: . . MGI: J:201893
Quarmyne M; Doan PL; Himburg HA; Yan X; Nakamura M; Zhao L; Chao NJ; Chute JP. 2015. Protein tyrosine phosphatase-sigma regulates hematopoietic stem cell-repopulating capacity.. In: . . MGI: J:219369
Quintana E; Shackleton M; Sabel MS; Fullen DR; Johnson TM; Morrison SJ. 2008. Efficient tumour formation by single human melanoma cells.. In: . . MGI: J:142408
Ramirez-Carrozzi V; Sambandam A; Luis E; Lin Z; Jeet S; Lesch J; Hackney J; Kim J; Zhou M; Lai J; Modrusan Z; Sai T; Lee W; Xu M; Caplazi P; Diehl L; de Voss J; Balazs M; Gonzalez L Jr; Singh H; Ouyang W; Pappu R. 2011. IL-17C regulates the innate immune function of epithelial cells in an autocrine manner.. In: . . MGI: J:178967
Ramsey C; Rubinstein MP; Kim DM; Cho JH; Sprent J; Surh CD. 2008. The lymphopenic environment of CD132 (common gamma-chain)-deficient hosts elicits rapid homeostatic proliferation of naive T cells via IL-15.. In: . . MGI: J:134238
Rappa G; Mercapide J; Lorico A. 2012. Spontaneous Formation of Tumorigenic Hybrids between Breast Cancer and Multipotent Stromal Cells Is a Source of Tumor Heterogeneity.. In: . . MGI: J:184798
Rauch DA; Hurchla MA; Harding JC; Deng H; Shea LK; Eagleton MC; Niewiesk S; Lairmore MD; Piwnica-Worms D; Rosol TJ; Weber JD; Ratner L; Weilbaecher KN. 2010. The ARF tumor suppressor regulates bone remodeling and osteosarcoma development in mice.. In: . . MGI: J:168312
Robbiani DF; Deroubaix S; Feldhahn N; Oliveira TY; Callen E; Wang Q; Jankovic M; Silva IT; Rommel PC; Bosque D; Eisenreich T; Nussenzweig A; Nussenzweig MC. 2015. Plasmodium Infection Promotes Genomic Instability and AID-Dependent B Cell Lymphoma.. In: . . MGI: J:224827
Rodgers JT; King KY; Brett JO; Cromie MJ; Charville GW; Maguire KK; Brunson C; Mastey N; Liu L; Tsai CR; Goodell MA; Rando TA. 2014. mTORC1 controls the adaptive transition of quiescent stem cells from G0 to G(Alert).. In: . . MGI: J:213273
Rosenberger CM; Clark AE; Treuting PM; Johnson CD; Aderem A. 2008. ATF3 regulates MCMV infection in mice by modulating IFN-gamma expression in natural killer cells.. In: . . MGI: J:132172
Rothfuchs AG; Trumstedt C; Wigzell H; Rottenberg ME. 2004. Intracellular bacterial infection-induced IFN-gamma is critically but not solely dependent on Toll-like receptor 4-myeloid differentiation factor 88-IFN-alpha beta-STAT1 signaling.. In: . . MGI: J:89856
Roy N; Takeuchi KK; Ruggeri JM; Bailey P; Chang D; Li J; Leonhardt L; Puri S; Hoffman MT; Gao S; Halbrook CJ; Song Y; Ljungman M; Malik S; Wright CV; Dawson DW; Biankin AV; Hebrok M; Crawford HC. 2016. PDX1 dynamically regulates pancreatic ductal adenocarcinoma initiation and maintenance.. In: . . MGI: J:238701
Sabet-Baktach M; Eggenhofer E; Rovira J; Renner P; Lantow M; Farkas SA; Malaise M; Edtinger K; Shaotang Z; Koehl GE; Dahlke MH; Schlitt HJ; Geissler EK; Kroemer A. 2013. Double deficiency for RORgammat and T-bet drives Th2-mediated allograft rejection in mice.. In: . . MGI: J:206252
Saddawi-Konefka R; Seelige R; Gross ET; Levy E; Searles SC; Washington A Jr; Santosa EK; Liu B; O'Sullivan TE; Harismendy O; Bui JD. 2016. Nrf2 Induces IL-17D to Mediate Tumor and Virus Surveillance.. In: . . MGI: J:239033
Saint Fleur S; Hoshino A; Kondo K; Egawa T; Fujii H. 2009. Regulation of Fas-mediated immune homeostasis by an activation-induced protein, Cyclon.. In: . . MGI: J:151722
Saito A; Henning MS; Serrao E; Dubose BN; Teng S; Huang J; Li X; Saito N; Roy SP; Siddiqui MA; Ahn J; Tsuji M; Hatziioannou T; Engelman AN; Yamashita M. 2016. Capsid-CPSF6 Interaction Is Dispensable for HIV-1 Replication in Primary Cells but Is Selected during Virus Passage In Vivo.. In: . . MGI: J:234650
Sander S; Calado DP; Srinivasan L; Kochert K; Zhang B; Rosolowski M; Rodig SJ; Holzmann K; Stilgenbauer S; Siebert R; Bullinger L; Rajewsky K. 2012. Synergy between PI3K signaling and MYC in Burkitt lymphomagenesis.. In: . . MGI: J:191824
Sandri S; Bobisse S; Moxley K; Lamolinara A; De Sanctis F; Boschi F; Sbarbati A; Fracasso G; Ferrarini G; Hendriks RW; Cavallini C; Scupoli MT; Sartoris S; Iezzi M; Nishimura MI; Bronte V; Ugel S. 2016. Feasibility of Telomerase-Specific Adoptive T-cell Therapy for B-cell Chronic Lymphocytic Leukemia and Solid Malignancies.. In: . . MGI: J:232028
Sanos SL; Bui VL; Mortha A; Oberle K; Heners C; Johner C; Diefenbach A. 2009. RORgammat and commensal microflora are required for the differentiation of mucosal interleukin 22-producing NKp46+ cells.. In: . . MGI: J:142348
Scheeren FA; Kuo AH; van Weele LJ; Cai S; Glykofridis I; Sikandar SS; Zabala M; Qian D; Lam JS; Johnston D; Volkmer JP; Sahoo D; van de Rijn M; Dirbas FM; Somlo G; Kalisky T; Rothenberg ME; Quake SR; Clarke MF. 2014. A cell-intrinsic role for TLR2-MYD88 in intestinal and breast epithelia and oncogenesis.. In: . . MGI: J:217693
Schroder PM; Khattar M; Baum CE; Miyahara Y; Chen W; Vyas R; Muralidharan S; Mierzejewska B; Stepkowski SM. 2015. PD-1-dependent restoration of self-tolerance in the NOD mouse model of diabetes after transient anti-TCRbeta mAb therapy.. In: . . MGI: J:220839
Schwab I; Biburger M; Kronke G; Schett G; Nimmerjahn F. 2012. IVIg-mediated amelioration of ITP in mice is dependent on sialic acid and SIGNR1.. In: . . MGI: J:187786
Seehus CR; Aliahmad P; de la Torre B; Iliev ID; Spurka L; Funari VA; Kaye J. 2015. The development of innate lymphoid cells requires TOX-dependent generation of a common innate lymphoid cell progenitor.. In: . . MGI: J:232838
Seif AE; Barrett DM; Milone M; Brown VI; Grupp SA; Reid GS. 2009. Long-term protection from syngeneic acute lymphoblastic leukemia by CpG ODN-mediated stimulation of innate and adaptive immune responses.. In: . . MGI: J:152910
Serafini N; Klein Wolterink RG; Satoh-Takayama N; Xu W; Vosshenrich CA; Hendriks RW; Di Santo JP. 2014. Gata3 drives development of RORgammat+ group 3 innate lymphoid cells.. In: . . MGI: J:208346
Sewald X; Ladinsky MS; Uchil PD; Beloor J; Pi R; Herrmann C; Motamedi N; Murooka TT; Brehm MA; Greiner DL; Shultz LD; Mempel TR; Bjorkman PJ; Kumar P; Mothes W. 2015. Retroviruses use CD169-mediated trans-infection of permissive lymphocytes to establish infection.. In: . . MGI: J:226540
Shang L; Hua H; Foo K; Martinez H; Watanabe K; Zimmer M; Kahler DJ; Freeby M; Chung W; LeDuc C; Goland R; Leibel RL; Egli D. 2014. beta-cell dysfunction due to increased ER stress in a stem cell model of Wolfram syndrome.. In: . . MGI: J:208989
Shen Y; Park CS; Suppipat K; Mistretta TA; Puppi M; Horton TM; Rabin K; Gray NS; Meijerink JPP; Lacorazza HD. 2017. Inactivation of KLF4 promotes T-cell acute lymphoblastic leukemia and activates the MAP2K7 pathway.. In: . . MGI: J:241802
Shukla A; Rai K; Shukla V; Chaturvedi NK; Bociek RG; Pirruccello SJ; Band H; Lu R; Joshi SS. 2016. Sprouty 2: a novel attenuator of B-cell receptor and MAPK-Erk signaling in CLL.. In: . . MGI: J:232635
Shukla V; Ma S; Hardy RR; Joshi SS; Lu R. 2013. A role for IRF4 in the development of CLL.. In: . . MGI: J:203270
Shultz LD; Ishikawa F; Greiner DL. 2007. Humanized mice in translational biomedical research.. In: . . MGI: J:142414
Shultz LD; Saito Y; Najima Y; Tanaka S; Ochi T; Tomizawa M; Doi T; Sone A; Suzuki N; Fujiwara H; Yasukawa M; Ishikawa F. 2010. Generation of functional human T-cell subsets with HLA-restricted immune responses in HLA class I expressing NOD/SCID/IL2r gamma(null) humanized mice.. In: . . MGI: J:162315
Simpson-Abelson MR; Sonnenberg GF; Takita H; Yokota SJ; Conway TF Jr; Kelleher RJ Jr; Shultz LD; Barcos M; Bankert RB. 2008. Long-term engraftment and expansion of tumor-derived memory T cells following the implantation of non-disrupted pieces of human lung tumor into NOD-scid IL2Rgamma(null) mice.. In: . . MGI: J:142412
Spranger S; Jeremias I; Wilde S; Leisegang M; Starck L; Mosetter B; Uckert W; Heemskerk MH; Schendel DJ; Frankenberger B. 2012. TCR-transgenic lymphocytes specific for HMMR/Rhamm limit tumor outgrowth in vivo.. In: . . MGI: J:183769
Stratford EW; Bostad M; Castro R; Skarpen E; Berg K; Hogset A; Myklebost O; Selbo PK. 2013. Photochemical internalization of CD133-targeting immunotoxins efficiently depletes sarcoma cells with stem-like properties and reduces tumorigenicity.. In: . . MGI: J:202381
Strowig T; Chijioke O; Carrega P; Arrey F; Meixlsperger S; Ramer PC; Ferlazzo G; Munz C. 2010. Human NK cells of mice with reconstituted human immune system components require preactivation to acquire functional competence.. In: . . MGI: J:167434
Strowig T; Gurer C; Ploss A; Liu YF; Arrey F; Sashihara J; Koo G; Rice CM; Young JW; Chadburn A; Cohen JI; Munz C. 2009. Priming of protective T cell responses against virus-induced tumors in mice with human immune system components.. In: . . MGI: J:149509
Suzuki K; Nakajima H; Saito Y; Saito T; Leonard WJ; Iwamoto I. 2000. Janus kinase 3 (Jak3) is essential for common cytokine receptor gamma chain (gamma(c))-dependent signaling: comparative analysis of gamma(c), Jak3, and gamma(c) and Jak3 double-deficient mice.. In: . . MGI: J:60418
Swaims AY; Khani F; Zhang Y; Roberts AI; Devadas S; Shi Y; Rabson AB. 2010. Immune activation induces immortalization of HTLV-1 LTR-Tax transgenic CD4+ T cells.. In: . . MGI: J:165866
Takagi S; Saito Y; Hijikata A; Tanaka S; Watanabe T; Hasegawa T; Mochizuki S; Kunisawa J; Kiyono H; Koseki H; Ohara O; Saito T; Taniguchi S; Shultz LD; Ishikawa F. 2012. Membrane-bound human SCF/KL promotes in vivo human hematopoietic engraftment and myeloid differentiation.. In: . . MGI: J:180274
Takatori H; Kanno Y; Watford WT; Tato CM; Weiss G; Ivanov II; Littman DR; O'Shea JJ. 2009. Lymphoid tissue inducer-like cells are an innate source of IL-17 and IL-22.. In: . . MGI: J:144034
Tanaka S; Saito Y; Kunisawa J; Kurashima Y; Wake T; Suzuki N; Shultz LD; Kiyono H; Ishikawa F. 2012. Development of mature and functional human myeloid subsets in hematopoietic stem cell-engrafted NOD/SCID/IL2rgammaKO mice.. In: . . MGI: J:188959
Tanno T; Lim Y; Wang Q; Chesi M; Bergsagel PL; Matthews G; Johnstone RW; Ghosh N; Borrello I; Huff CA; Matsui W. 2014. Growth differentiating factor 15 enhances the tumor-initiating and self-renewal potential of multiple myeloma cells.. In: . . MGI: J:208701
Taylor JJ; Martinez RJ; Titcombe PJ; Barsness LO; Thomas SR; Zhang N; Katzman SD; Jenkins MK; Mueller DL. 2012. Deletion and anergy of polyclonal B cells specific for ubiquitous membrane-bound self-antigen.. In: . . MGI: J:190897
Taylor RT; Lugering A; Newell KA; Williams IR. 2004. Intestinal cryptopatch formation in mice requires lymphotoxin alpha and the lymphotoxin beta receptor.. In: . . MGI: J:94865
The Jackson Laboratory. 2005. Information obtained from The Jackson Laboratory, Bar Harbor, ME. In: . . MGI: J:101977
Thomas MF; Abdul-Wajid S; Panduro M; Babiarz JE; Rajaram M; Woodruff P; Lanier LL; Heissmeyer V; Ansel KM. 2012. Eri1 regulates microRNA homeostasis and mouse lymphocyte development and antiviral function.. In: . . MGI: J:189125
Thomas SY; Scanlon ST; Griewank KG; Constantinides MG; Savage AK; Barr KA; Meng F; Luster AD; Bendelac A. 2011. PLZF induces an intravascular surveillance program mediated by long-lived LFA-1-ICAM-1 interactions.. In: . . MGI: J:176822
Todorova D; Kim J; Hamzeinejad S; He J; Xu Y. 2016. Brief Report: Immune Microenvironment Determines the Immunogenicity of Induced Pluripotent Stem Cell Derivatives.. In: . . MGI: J:233079
Tolar J; Wang X; Braunlin E; McElmurry RT; Nakamura Y; Bell S; Xia L; Zhang J; Hu Q; Panoskaltsis-Mortari A; Zhang J; Blazar BR. 2007. The host immune response is essential for the beneficial effect of adult stem cells after myocardial ischemia.. In: . . MGI: J:123112
Torreggiani E; Matthews BG; Pejda S; Matic I; Horowitz MC; Grcevic D; Kalajzic I. 2013. Preosteocytes/osteocytes have the potential to dedifferentiate becoming a source of osteoblasts.. In: . . MGI: J:207546
Touma M; Sun ZY; Clayton LK; Marissen WE; Kruisbeek AM; Wagner G; Reinherz EL. 2007. Importance of the CD3gamma ectodomain terminal beta-strand and membrane proximal stalk in thymic development and receptor assembly.. In: . . MGI: J:144281
Ueno S; Lu J; He J; Li A; Zhang X; Ritz J; Silberstein LE; Chai L. 2014. Aberrant expression of SALL4 in acute B cell lymphoblastic leukemia: mechanism, function, and implication for a potential novel therapeutic target.. In: . . MGI: J:215705
Unsinger J; McDonough JS; Shultz LD; Ferguson TA; Hotchkiss RS. 2009. Sepsis-induced human lymphocyte apoptosis and cytokine production in 'humanized' mice.. In: . . MGI: J:151270
Unzu C; Melero I; Morales-Kastresana A; Sampedro A; Serrano-Mendioroz I; Azpilikueta A; Ochoa MC; Dubrot J; Martinez-Anso E; Fontanellas A. 2014. Innate functions of immunoglobulin M lessen liver gene transfer with helper-dependent adenovirus.. In: . . MGI: J:212341
Vanner RJ; Remke M; Gallo M; Selvadurai HJ; Coutinho F; Lee L; Kushida M; Head R; Morrissy S; Zhu X; Aviv T; Voisin V; Clarke ID; Li Y; Mungall AJ; Moore RA; Ma Y; Jones SJ; Marra MA; Malkin D; Northcott PA; Kool M; Pfister SM; Bader G; Hochedlinger K; Korshunov A; Taylor MD; Dirks PB. 2014. Quiescent sox2(+) cells drive hierarchical growth and relapse in sonic hedgehog subgroup medulloblastoma.. In: . . MGI: J:213713
Veinotte LL; Halim TY; Takei F. 2008. Unique subset of natural killer cells develops from progenitors in lymph node.. In: . . MGI: J:134359
Viatour P; Ehmer U; Saddic LA; Dorrell C; Andersen JB; Lin C; Zmoos AF; Mazur PK; Schaffer BE; Ostermeier A; Vogel H; Sylvester KG; Thorgeirsson SS; Grompe M; Sage J. 2011. Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway.. In: . . MGI: J:177573
Vujanovic L; Szymkowski DE; Alber S; Watkins SC; Vujanovic NL; Butterfield LH. 2010. Virally infected and matured human dendritic cells activate natural killer cells via cooperative activity of plasma membrane-bound TNF and IL-15.. In: . . MGI: J:162797
Wallington-Beddoe CT; Powell JA; Tong D; Pitson SM; Bradstock KF; Bendall LJ. 2014. Sphingosine kinase 2 promotes acute lymphoblastic leukemia by enhancing MYC expression.. In: . . MGI: J:212466
Wang LX; Kang G; Kumar P; Lu W; Li Y; Zhou Y; Li Q; Wood C. 2014. Humanized-BLT mouse model of Kaposi's sarcoma-associated herpesvirus infection.. In: . . MGI: J:206819
Waskow C; Bartels S; Schlenner SM; Costa C; Rodewald HR. 2007. Kit is essential for PMA-inflammation-induced mast-cell accumulation in the skin.. In: . . MGI: J:145426
Wei C; Zeff R; Goldschneider I. 2000. Murine pro-B cells require IL-7 and its receptor complex to up-regulate IL-7R alpha, terminal deoxynucleotidyltransferase, and c mu expression.. In: . . MGI: J:60331
Wei S; Kozono S; Kats L; Nechama M; Li W; Guarnerio J; Luo M; You MH; Yao Y; Kondo A; Hu H; Bozkurt G; Moerke NJ; Cao S; Reschke M; Chen CH; Rego EM; Lo-Coco F; Cantley LC; Lee TH; Wu H; Zhang Y; Pandolfi PP; Zhou XZ; Lu KP. 2015. Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer.. In: . . MGI: J:228245
White RE; Ramer PC; Naresh KN; Meixlsperger S; Pinaud L; Rooney C; Savoldo B; Coutinho R; Bodor C; Gribben J; Ibrahim HA; Bower M; Nourse JP; Gandhi MK; Middeldorp J; Cader FZ; Murray P; Munz C; Allday MJ. 2012. EBNA3B-deficient EBV promotes B cell lymphomagenesis in humanized mice and is found in human tumors.. In: . . MGI: J:184554
Whitfield-Larry F; Young EF; Talmage G; Fudge E; Azam A; Patel S; Largay J; Byrd W; Buse J; Calikoglu AS; Shultz LD; Frelinger JA. 2011. HLA-A2-matched peripheral blood mononuclear cells from type 1 diabetic patients, but not nondiabetic donors, transfer insulitis to NOD-scid/gammac(null)/HLA-A2 transgenic mice concurrent with the expansion of islet-specific CD8+ T cells.. In: . . MGI: J:177952
Wilhelm C; Hirota K; Stieglitz B; Van Snick J; Tolaini M; Lahl K; Sparwasser T; Helmby H; Stockinger B. 2011. An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammation.. In: . . MGI: J:177640
Willimsky G; Schmidt K; Loddenkemper C; Gellermann J; Blankenstein T. 2013. Virus-induced hepatocellular carcinomas cause antigen-specific local tolerance.. In: . . MGI: J:196378
Wu X; Kastin AJ; Hsuchou H; Pan W. 2010. The effects of IL2Rgamma knockout on depression and contextual memory.. In: . . MGI: J:161861
Wunderlich M; Brooks RA; Panchal R; Rhyasen GW; Danet-Desnoyers G; Mulloy JC. 2014. OKT3 prevents xenogeneic GVHD and allows reliable xenograft initiation from unfractionated human hematopoietic tissues.. In: . . MGI: J:217446
Wunderlich M; Chou FS; Link KA; Mizukawa B; Perry RL; Carroll M; Mulloy JC. 2010. AML xenograft efficiency is significantly improved in NOD/SCID-IL2RG mice constitutively expressing human SCF, GM-CSF and IL-3.. In: . . MGI: J:166359
Xie H; Xu J; Hsu JH; Nguyen M; Fujiwara Y; Peng C; Orkin SH. 2014. Polycomb repressive complex 2 regulates normal hematopoietic stem cell function in a developmental-stage-specific manner.. In: . . MGI: J:205522
Xie J; Broxmeyer HE; Feng D; Schweitzer KS; Yi R; Cook TG; Chitteti BR; Barwinska D; Traktuev DO; Van Demark MJ; Justice MJ; Ou X; Srour EF; Prockop DJ; Petrache I; March KL. 2015. Human adipose-derived stem cells ameliorate cigarette smoke-induced murine myelosuppression via secretion of TSG-6.. In: . . MGI: J:223580
Xie Y; Akpinarli A; Maris C; Hipkiss EL; Lane M; Kwon EK; Muranski P; Restifo NP; Antony PA. 2010. Naive tumor-specific CD4(+) T cells differentiated in vivo eradicate established melanoma.. In: . . MGI: J:158128
Xu L; Mohammad KS; Wu H; Crean C; Poteat B; Cheng Y; Cardoso AA; Machal C; Hanenberg H; Abonour R; Kacena MA; Chirgwin J; Suvannasankha A; Srour EF. 2016. Cell Adhesion Molecule CD166 Drives Malignant Progression and Osteolytic Disease in Multiple Myeloma.. In: . . MGI: J:237854
Xu X; Weiss ID; Zhang HH; Singh SP; Wynn TA; Wilson MS; Farber JM. 2014. Conventional NK cells can produce IL-22 and promote host defense in Klebsiella pneumoniae pneumonia.. In: . . MGI: J:209361
XuFeng R; Boyer MJ; Shen H; Li Y; Yu H; Gao Y; Yang Q; Wang Q; Cheng T. 2009. ADAR1 is required for hematopoietic progenitor cell survival via RNA editing.. In: . . MGI: J:153698
Yamaoka K; Min B; Zhou YJ; Paul WE; O'shea JJ. 2005. Jak3 negatively regulates dendritic-cell cytokine production and survival.. In: . . MGI: J:123902
Yamauchi T; Takenaka K; Urata S; Shima T; Kikushige Y; Tokuyama T; Iwamoto C; Nishihara M; Iwasaki H; Miyamoto T; Honma N; Nakao M; Matozaki T; Akashi K. 2013. Polymorphic Sirpa is the genetic determinant for NOD-based mouse lines to achieve efficient human cell engraftment.. In: . . MGI: J:194763
Yang C; Loehn M; Jurczyk A; Przewozniak N; Leehy L; Herrera PL; Shultz LD; Greiner DL; Harlan DM; Bortell R. 2015. Lixisenatide accelerates restoration of normoglycemia and improves human beta-cell function and survival in diabetic immunodeficient NOD-scid IL-2rg(null) RIP-DTR mice engrafted with human islets.. In: . . MGI: J:225120
Yang L; Chen G; Mohanty S; Scott G; Fazal F; Rahman A; Begum S; Hynes RO; Xu L. 2011. GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression.. In: . . MGI: J:175446
Yang L; Friedland S; Corson N; Xu L. 2014. GPR56 inhibits melanoma growth by internalizing and degrading its ligand TG2.. In: . . MGI: J:208172
Yang Q; Li F; Harly C; Xing S; Ye L; Xia X; Wang H; Wang X; Yu S; Zhou X; Cam M; Xue HH; Bhandoola A. 2015. TCF-1 upregulation identifies early innate lymphoid progenitors in the bone marrow.. In: . . MGI: J:233391
Yoshioka T; Otero J; Chen Y; Kim YM; Koutcher JA; Satagopan J; Reuter V; Carver B; de Stanchina E; Enomoto K; Greenberg NM; Scardino PT; Scher HI; Sawyers CL; Giancotti FG. 2013. beta4 Integrin signaling induces expansion of prostate tumor progenitors.. In: . . MGI: J:194482
Yu G; Xu X; Vu MD; Kilpatrick ED; Li XC. 2006. NK cells promote transplant tolerance by killing donor antigen-presenting cells.. In: . . MGI: J:124395
Zavidij O; Ball CR; Herbst F; Fessler S; Schmidt M; von Kalle C; Glimm H. 2010. Hematopoietic activity of human short-term repopulating cells in mobilized peripheral blood cell transplants is restricted to the first 5 months after transplantation.. In: . . MGI: J:161539
Zecher D; Li Q; Oberbarnscheidt MH; Demetris AJ; Shlomchik WD; Rothstein DM; Lakkis FG. 2010. NK cells delay allograft rejection in lymphopenic hosts by downregulating the homeostatic proliferation of CD8+ T cells.. In: . . MGI: J:161405
Zemp FJ; McKenzie BA; Lun X; Reilly KM; McFadden G; Yong VW; Forsyth PA. 2014. Cellular factors promoting resistance to effective treatment of glioma with oncolytic myxoma virus.. In: . . MGI: J:218088
Zenewicz LA; Yancopoulos GD; Valenzuela DM; Murphy AJ; Stevens S; Flavell RA. 2008. Innate and adaptive interleukin-22 protects mice from inflammatory bowel disease.. In: . . MGI: J:142640
Zhang B; Strauss AC; Chu S; Li M; Ho Y; Shiang KD; Snyder DS; Huettner CS; Shultz L; Holyoake T; Bhatia R. 2010. Effective targeting of quiescent chronic myelogenous leukemia stem cells by histone deacetylase inhibitors in combination with imatinib mesylate.. In: . . MGI: J:160523
Zhang H; Watanabe R; Berry GJ; Vaglio A; Liao YJ; Warrington KJ; Goronzy JJ; Weyand CM. 2017. Immunoinhibitory checkpoint deficiency in medium and large vessel vasculitis.. In: . . MGI: J:240876
Zhang H; Zhou X; McQuade T; Li J; Chan FK; Zhang J. 2011. Functional complementation between FADD and RIP1 in embryos and lymphocytes.. In: . . MGI: J:170816
Zhang Q; Hossain DM; Duttagupta P; Moreira D; Zhao X; Won H; Buettner R; Nechaev S; Majka M; Zhang B; Cai Q; Swiderski P; Kuo YH; Forman S; Marcucci G; Kortylewski M. 2016. Serum-resistant CpG-STAT3 decoy for targeting survival and immune checkpoint signaling in acute myeloid leukemia.. In: . . MGI: J:232638
Zhang X; Wan G; Mlotshwa S; Vance V; Berger FG; Chen H; Lu X. 2010. Oncogenic Wip1 phosphatase is inhibited by miR-16 in the DNA damage signaling pathway.. In: . . MGI: J:164245
Zhao Y; Guo C; Hwang D; Lin B; Dingeldein M; Mihailescu D; Sam S; Sidhwani S; Zhang Y; Jain S; Skidgel RA; Prabhakar BS; Mazzone T; Holterman MJ. 2010. Selective destruction of mouse islet beta cells by human T lymphocytes in a newly-established humanized type 1 diabetic model.. In: . . MGI: J:164900
Zhou S; Mody D; DeRavin SS; Hauer J; Lu T; Ma Z; Hacein-Bey Abina S; Gray JT; Greene MR; Cavazzana-Calvo M; Malech HL; Sorrentino BP. 2010. A self-inactivating lentiviral vector for SCID-X1 gene therapy that does not activate LMO2 expression in human T cells.. In: . . MGI: J:163500
van der Touw W; Cravedi P; Kwan WH; Paz-Artal E; Merad M; Heeger PS. 2013. Cutting edge: Receptors for C3a and C5a modulate stability of alloantigen-reactive induced regulatory T cells.. In: . . MGI: J:204834

Additional - Prkdc^scid related

Accardi R; Gruffat H; Sirand C; Fusil F; Gheit T; Hernandez-Vargas H; Le Calvez-Kelm F; Traverse-Glehen A; Cosset FL; Manet E; Wild CP; Tommasino M. 2015. The mycotoxin aflatoxin B1 stimulates Epstein-Barr virus-induced B-cell transformation in in vitro and in vivo experimental models.. In: . . MGI: J:226625
Agerstam H; Jaras M; Andersson A; Johnels P; Hansen N; Lassen C; Rissler M; Gisselsson D; Olofsson T; Richter J; Fan X; Ehinger M; Fioretos T. 2010. Modeling the human 8p11-myeloproliferative syndrome in immunodeficient mice.. In: . . MGI: J:164507
Agliano A; Martin-Padura I; Mancuso P; Marighetti P; Rabascio C; Pruneri G; Shultz LD; Bertolini F. 2008. Human acute leukemia cells injected in NOD/LtSz-scid/IL-2Rgamma null mice generate a faster and more efficient disease compared to other NOD/scid-related strains.. In: . . MGI: J:142410
Ahsmann EJ; van Tol MJ; Oudeman-Gruber J; Lokhorst H; Uytdehaag FG; Schuurman HJ; Bloem AC. 1995. The SCID mouse as a model for multiple myeloma.. In: . . MGI: J:22989
Akiba H; Takeda K; Kojima Y; Usui Y; Harada N; Yamazaki T; Ma J; Tezuka K; Yagita H; Okumura K. 2005. The role of ICOS in the CXCR5+ follicular B helper T cell maintenance in vivo.. In: . . MGI: J:107507
Al-Qaoud KM; Fleischer B; Hoerauf A. 1998. The Xid defect imparts susceptibility to experimental murine filariosis--association with a lack of antibody and IL-10 production by B cells in response to phosphorylcholine.. In: . . MGI: J:110480
Alba A; Puertas MC; Carrillo J; Planas R; Ampudia R; Pastor X; Bosch F; Pujol-Borrell R; Verdaguer J; Vives-Pi M. 2004. IFNbeta accelerates autoimmune type 1 diabetes in nonobese diabetic mice and breaks the tolerance to beta cells in nondiabetes-prone mice.. In: . . MGI: J:94366
Alfaro MP; Pagni M; Vincent A; Atkinson J; Hill MF; Cates J; Davidson JM; Rottman J; Lee E; Young PP. 2008. The Wnt modulator sFRP2 enhances mesenchymal stem cell engraftment, granulation tissue formation and myocardial repair.. In: . . MGI: J:142215
Ali N; Flutter B; Sanchez Rodriguez R; Sharif-Paghaleh E; Barber LD; Lombardi G; Nestle FO. 2012. Xenogeneic graft-versus-host-disease in NOD-scid IL-2Rgammanull mice display a T-effector memory phenotype.. In: . . MGI: J:191672
Alugupalli KR; Gerstein RM; Chen J; Szomolanyi-Tsuda E; Woodland RT; Leong JM. 2003. The resolution of relapsing fever borreliosis requires IgM and is concurrent with expansion of B1b lymphocytes.. In: . . MGI: J:125443
Amarnath S; Foley JE; Farthing DE; Gress RE; Laurence A; Eckhaus MA; Metais JY; Rose JJ; Hakim FT; Felizardo TC; Cheng AV; Robey PG; Stroncek DE; Sabatino M; Battiwalla M; Ito S; Fowler DH; Barrett AJ. 2015. Bone marrow-derived mesenchymal stromal cells harness purinergenic signaling to tolerize human Th1 cells in vivo.. In: . . MGI: J:224046
Ambrosino E; Spadaro M; Iezzi M; Curcio C; Forni G; Musiani P; Wei WZ; Cavallo F. 2006. Immunosurveillance of Erbb2 carcinogenesis in transgenic mice is concealed by a dominant regulatory T-cell self-tolerance.. In: . . MGI: J:112102
Amezcua Vesely MC; Schwartz M; Bermejo DA; Montes CL; Cautivo KM; Kalergis AM; Rawlings DJ; Acosta-Rodriguez EV; Gruppi A. 2012. FcgammaRIIb and BAFF differentially regulate peritoneal B1 cell survival.. In: . . MGI: J:188666
Amrani A; Verdaguer J; Anderson B; Utsugi T; Bou S; Santamaria P. 1999. Perforin-independent beta-cell destruction by diabetogenic CD8(+) T lymphocytes in transgenic nonobese diabetic mice.. In: . . MGI: J:108737
Anders K; Buschow C; Herrmann A; Milojkovic A; Loddenkemper C; Kammertoens T; Daniel P; Yu H; Charo J; Blankenstein T. 2011. Oncogene-Targeting T Cells Reject Large Tumors while Oncogene Inactivation Selects Escape Variants in Mouse Models of Cancer.. In: . . MGI: J:178597
Anderson MG; Nair KS; Amonoo LA; Mehalow A; Trantow CM; Masli S; John SW. 2008. GpnmbR150X allele must be present in bone marrow derived cells to mediate DBA/2J glaucoma.. In: . . MGI: J:134670
Andoh M; Zhang G; Russell-Lodrigue KE; Shive HR; Weeks BR; Samuel JE. 2007. T Cells Are Essential for Bacterial Clearance, and Gamma Interferon, Tumor Necrosis Factor Alpha, and B Cells Are Crucial for Disease Development in Coxiella burnetii Infection in Mice.. In: . . MGI: J:122426
Andre MC; Erbacher A; Gille C; Schmauke V; Goecke B; Hohberger A; Mang P; Wilhelm A; Mueller I; Herr W; Lang P; Handgretinger R; Hartwig UF. 2010. Long-term human CD34(+) stem cell-engrafted nonobese diabetic/SCID/IL-2Rgamma(null) mice show impaired CD8(+) T cell maintenance and a functional arrest of immature NK cells.. In: . . MGI: J:163262
Araki R; Fujimori A; Hamatani K; Mita K; Saito T; Mori M; Fukumura R; Morimyo M; Muto M; Itoh M; Tatsumi K; Abe M. 1997. Nonsense mutation at Tyr-4046 in the DNA-dependent protein kinase catalytic subunit of severe combined immune deficiency mice.. In: . . MGI: J:39329
Archer NK; Harro JM; Shirtliff ME. 2013. Clearance of Staphylococcus aureus nasal carriage is T cell dependent and mediated through interleukin-17A expression and neutrophil influx.. In: . . MGI: J:199531
Arendt LM; McCready J; Keller PJ; Baker DD; Naber SP; Seewaldt V; Kuperwasser C. 2013. Obesity promotes breast cancer by CCL2-mediated macrophage recruitment and angiogenesis.. In: . . MGI: J:202607
Ashkar AA; Di Santo JP; Croy BA. 2000. Interferon gamma contributes to initiation of uterine vascular modification, decidual integrity, and uterine natural killer cell maturation during normal murine pregnancy [see comments]. In: . . MGI: J:63645
Aspord C; Rome S; Thivolet C. 2004. Early events in islets and pancreatic lymph nodes in autoimmune diabetes.. In: . . MGI: J:91668
Augstein P; Stephens LA; Allison J; Elefanty AG; Ekberg M; Kay TW; Harrison LC. 1998. Beta-cell apoptosis in an accelerated model of autoimmune diabetes.. In: . . MGI: J:133840
Babu S; Porte P; Klei TR; Shultz LD; Rajan TV. 1998. Host NK cells are required for the growth of the human filarial parasite Brugia malayi in mice.. In: . . MGI: J:49819
Baerenwaldt A; Lux A; Danzer H; Spriewald BM; Ullrich E; Heidkamp G; Dudziak D; Nimmerjahn F. 2011. Fcgamma receptor IIB (FcgammaRIIB) maintains humoral tolerance in the human immune system in vivo.. In: . . MGI: J:180174
Baker RL; Delong T; Barbour G; Bradley B; Nakayama M; Haskins K. 2013. Cutting edge: CD4 T cells reactive to an islet amyloid polypeptide peptide accumulate in the pancreas and contribute to disease pathogenesis in nonobese diabetic mice.. In: . . MGI: J:206266
Balasa B; La Cava A; Van Gunst K; Mocnik L; Balakrishna D; Nguyen N; Tucker L; Sarvetnick N. 2000. A mechanism for IL-10-mediated diabetes in the nonobese diabetic (NOD) mouse: ICAM-1 deficiency blocks accelerated diabetes. In: . . MGI: J:66103
Balavenkatraman KK; Aceto N; Britschgi A; Mueller U; Bence KK; Neel BG; Bentires-Alj M. 2011. Epithelial protein-tyrosine phosphatase 1B contributes to the induction of mammary tumors by HER2/Neu but is not essential for tumor maintenance.. In: . . MGI: J:205401
Baleriola J; Suarez T; de la Rosa EJ. 2010. DNA-PK promotes the survival of young neurons in the embryonic mouse retina.. In: . . MGI: J:186357
Ballas ZK; Buchta CM; Rosean TR; Heusel JW; Shey MR. 2013. Role of NK cell subsets in organ-specific murine melanoma metastasis.. In: . . MGI: J:204234
Bandeira M; Santos CS; de Azevedo EC; Soares LM; Macedo JO; Marchi S; da Silva CL; Chagas-Junior AD; McBride AJ; McBride FW; Reis MG; Athanazio DA. 2011. Attenuated Nephritis in Inducible Nitric Oxide Synthase Knockout C57BL/6 Mice and Pulmonary Hemorrhage in CB17 SCID and Recombination Activating Gene 1 Knockout C57BL/6 Mice Infected with Leptospira interrogans.. In: . . MGI: J:173478
Bandi S; Joseph B; Berishvili E; Singhania R; Wu YM; Cheng K; Gupta S. 2011. Perturbations in ataxia telangiectasia mutant signaling pathways after drug-induced acute liver failure and their reversal during rescue of animals by cell therapy.. In: . . MGI: J:168235
Banerjee P; Tripp A; Lairmore MD; Crawford L; Sieburg M; Ramos JC; Harrington W Jr; Beilke MA; Feuer G. 2010. Adult T-cell leukemia/lymphoma development in HTLV-1-infected humanized SCID mice.. In: . . MGI: J:162610
Banga SS; Hall KT; Sandhu AK; Weaver DT; Athwal RS. 1994. Complementation of V(D)J recombination defect and X-ray sensitivity of scid mouse cells by human chromosome 8.. In: . . MGI: J:21219
Banuelos SJ; Shultz LD; Greiner DL; Burzenski LM; Gott B; Lyons BL; Rossini AA; Appel MC. 2004. Rejection of human islets and human HLA-A2.1 transgenic mouse islets by alloreactive human lymphocytes in immunodeficient NOD-scid and NOD-Rag1(null)Prf1(null) mice.. In: . . MGI: J:91764
Bao L; Haas M; Pippin J; Wang Y; Miwa T; Chang A; Minto AW; Petkova M; Qiao G; Song WC; Alpers CE; Zhang J; Shankland SJ; Quigg RJ. 2009. Focal and segmental glomerulosclerosis induced in mice lacking decay-accelerating factor in T cells.. In: . . MGI: J:149592
Barber RC; Miccoli L; van Buul PP; Burr KL; van Duyn-Goedhart A; Angulo JF; Dubrova YE. 2004. Germline mutation rates at tandem repeat loci in DNA-repair deficient mice.. In: . . MGI: J:93788
Bardeesy N; Kim M; Xu J; Kim RS; Shen Q; Bosenberg MW; Wong WH; Chin L. 2005. Role of epidermal growth factor receptor signaling in RAS-driven melanoma.. In: . . MGI: J:99136
Barrette B; Hebert MA; Filali M; Lafortune K; Vallieres N; Gowing G; Julien JP; Lacroix S. 2008. Requirement of myeloid cells for axon regeneration.. In: . . MGI: J:142759
Barroso-delJesus A; Lucena-Aguilar G; Sanchez L; Ligero G; Gutierrez-Aranda I; Menendez P. 2011. The Nodal inhibitor Lefty is negatively modulated by the microRNA miR-302 in human embryonic stem cells.. In: . . MGI: J:172780
Barthold SW; Hodzic E; Tunev S; Feng S. 2006. Antibody-mediated disease remission in the mouse model of lyme borreliosis.. In: . . MGI: J:112329
Battaglia M; Stabilini A; Draghici E; Migliavacca B; Gregori S; Bonifacio E; Roncarolo MG. 2006. Induction of Tolerance in Type 1 Diabetes via Both CD4+CD25+ T Regulatory Cells and T Regulatory Type 1 Cells.. In: . . MGI: J:111884
Beamer WG; Shultz KL; Tennent BJ; Shultz LD. 1993. Granulosa cell tumorigenesis in genetically hypogonadal-immunodeficient mice grafted with ovaries from tumor-susceptible donors.. In: . . MGI: J:14443
Belkaid Y; Mendez S; Lira R; Kadambi N; Milon G; Sacks D. 2000. A natural model of Leishmania major infection reveals a prolonged 'silent' phase of parasite amplification in the skin before the onset of lesion formation and immunity.. In: . . MGI: J:120233
Bellani MA; Romanienko PJ; Cairatti DA; Camerini-Otero RD. 2005. SPO11 is required for sex-body formation, and Spo11 heterozygosity rescues the prophase arrest of Atm-/- spermatocytes.. In: . . MGI: J:100203
Bello-Irizarry SN; Wang J; Johnston CJ; Gigliotti F; Wright TW. 2014. MyD88 signaling regulates both host defense and immunopathogenesis during pneumocystis infection.. In: . . MGI: J:207087
Benavente CA; McEvoy JD; Finkelstein D; Wei L; Kang G; Wang YD; Neale G; Ragsdale S; Valentine V; Bahrami A; Temirov J; Pounds S; Zhang J; Dyer MA. 2013. Cross-species genomic and epigenomic landscape of retinoblastoma.. In: . . MGI: J:207640
Benner EJ; Banerjee R; Reynolds AD; Sherman S; Pisarev VM; Tsiperson V; Nemachek C; Ciborowski P; Przedborski S; Mosley RL; Gendelman HE. 2008. Nitrated alpha-Synuclein Immunity Accelerates Degeneration of Nigral Dopaminergic Neurons.. In: . . MGI: J:131300
Bertin A. 1992. Comparison of susceptibility of inbred and outbred infant mice to Escherichia coli heat-stable enterotoxin STa.. In: . . MGI: J:2117
Bettini M; Castellaw AH; Lennon GP; Burton AR; Vignali DA. 2012. Prevention of autoimmune diabetes by ectopic pancreatic beta-cell expression of interleukin-35.. In: . . MGI: J:196852
Biedermann KA; Sun JR; Giaccia AJ; Tosto LM; Brown JM. 1991. scid mutation in mice confers hypersensitivity to ionizing radiation and a deficiency in DNA double-strand break repair.. In: . . MGI: J:89590
Billerbeck E; Horwitz JA; Labitt RN; Donovan BM; Vega K; Budell WC; Koo GC; Rice CM; Ploss A. 2013. Characterization of human antiviral adaptive immune responses during hepatotropic virus infection in HLA-transgenic human immune system mice.. In: . . MGI: J:205706
Binder GK; Griffin DE. 2001. Interferon-gamma-mediated site-specific clearance of alphavirus from CNS neurons.. In: . . MGI: J:125465
Bitsaktsis C; Huntington J; Winslow G. 2004. Production of IFN-gamma by CD4 T cells is essential for resolving ehrlichia infection.. In: . . MGI: J:90518
Blanc L; Ciciotte SL; Gwynn B; Hildick-Smith GJ; Pierce EL; Soltis KA; Cooney JD; Paw BH; Peters LL. 2012. Critical function for the Ras-GTPase activating protein RASA3 in vertebrate erythropoiesis and megakaryopoiesis.. In: . . MGI: J:186485
Blunt T; Gell D; Fox M; Taccioli GE; Lehmann AR; Jackson SP; Jeggo PA. 1996. Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse.. In: . . MGI: J:35393
Bobbala D; Chen XL; Leblanc C; Mayhue M; Stankova J; Tanaka T; Chen YG; Ilangumaran S; Ramanathan S. 2012. Interleukin-15 plays an essential role in the pathogenesis of autoimmune diabetes in the NOD mouse.. In: . . MGI: J:191833
Bobbala D; Kandhi R; Chen X; Mayhue M; Bouchard E; Yan J; Knecht H; Barabe F; Ramanathan S; Ilangumaran S. 2016. Interleukin-15 deficiency promotes the development of T-cell acute lymphoblastic leukemia in non-obese diabetes mice with severe combined immunodeficiency.. In: . . MGI: J:233962
Boggiatto PM; Jie F; Ghosh M; Gibson-Corley KN; Ramer-Tait AE; Jones DE; Petersen CA. 2009. Altered dendritic cell phenotype in response to Leishmania amazonensis amastigote infection is mediated by MAP kinase, ERK.. In: . . MGI: J:147971
Bogue MA; Zhu C; Aguilar-Cordova E; Donehower LA; Roth DB. 1996. p53 is required for both radiation-induced differentiation and rescue of V(D)J rearrangement in scid mouse thymocytes.. In: . . MGI: J:31868
Boitano AE; Wang J; Romeo R; Bouchez LC; Parker AE; Sutton SE; Walker JR; Flaveny CA; Perdew GH; Denison MS; Schultz PG; Cooke MP. 2010. Aryl hydrocarbon receptor antagonists promote the expansion of human hematopoietic stem cells.. In: . . MGI: J:167433
Boldizsar F; Tarjanyi O; Nemeth P; Mikecz K; Glant TT. 2009. Th1/Th17 polarization and acquisition of an arthritogenic phenotype in arthritis-susceptible BALB/c, but not in MHC-matched, arthritis-resistant DBA/2 mice.. In: . . MGI: J:148186
Bolz DD; Sundsbak RS; Ma Y; Akira S; Kirschning CJ; Zachary JF; Weis JH; Weis JJ. 2004. MyD88 plays a unique role in host defense but not arthritis development in Lyme disease.. In: . . MGI: J:92031
Bolz DD; Sundsbak RS; Ma Y; Akira S; Weis JH; Schwan TG; Weis JJ. 2006. Dual role of MyD88 in rapid clearance of relapsing fever Borrelia spp.. In: . . MGI: J:116070
Bonifazi P; Zelante T; D'Angelo C; De Luca A; Moretti S; Bozza S; Perruccio K; Iannitti RG; Giovannini G; Volpi C; Fallarino F; Puccetti P; Romani L. 2009. Balancing inflammation and tolerance in vivo through dendritic cells by the commensal Candida albicans.. In: . . MGI: J:193381
Bosma GC; Custer RP; Bosma MJ. 1983. A severe combined immunodeficiency mutation in the mouse.. In: . . MGI: J:6958
Bosma GC; Oshinsky J; Kiefer K; Nakajima PB; Charan D; Congelton C; Radic M; Bosma MJ. 2006. Development of functional B cells in a line of SCID mice with transgenes coding for anti-double-stranded DNA antibody.. In: . . MGI: J:126632
Bosma M; Schuler W; Bosma G. 1988. The scid mouse mutant.. In: . . MGI: J:9341
Boyartchuk V; Rojas M; Yan BS; Jobe O; Hurt N; Dorfman DM; Higgins DE; Dietrich WF; Kramnik I. 2004. The host resistance locus sst1 controls innate immunity to Listeria monocytogenes infection in immunodeficient mice.. In: . . MGI: J:93705
Brackett CM; Kojouharov B; Veith J; Greene KF; Burdelya LG; Gollnick SO; Abrams SI; Gudkov AV. 2016. Toll-like receptor-5 agonist, entolimod, suppresses metastasis and induces immunity by stimulating an NK-dendritic-CD8+ T-cell axis.. In: . . MGI: J:230433
Braumuller H; Wieder T; Brenner E; Assmann S; Hahn M; Alkhaled M; Schilbach K; Essmann F; Kneilling M; Griessinger C; Ranta F; Ullrich S; Mocikat R; Braungart K; Mehra T; Fehrenbacher B; Berdel J; Niessner H; Meier F; van den Broek M; Haring HU; Handgretinger R; Quintanilla-Martinez L; Fend F; Pesic M; Bauer J; Zender L; Schaller M; Schulze-Osthoff K; Rocken M. 2013. T-helper-1-cell cytokines drive cancer into senescence.. In: . . MGI: J:194546
Bregenholt S; Claesson MH. 1998. Increased intracellular Th1 cytokines in scid mice with inflammatory bowel disease.. In: . . MGI: J:45906
Bregenholt S; Claesson MH. 1998. Splenic T helper cell type 1 cytokine profile and extramedullary haematopoiesis in severe combined immunodeficient (scid) mice with inflammatory bowel disease (IBD).. In: . . MGI: J:45450
Brehm MA; Racki WJ; Leif J; Burzenski L; Hosur V; Wetmore A; Gott B; Herlihy M; Ignotz R; Dunn R; Shultz LD; Greiner DL. 2012. Engraftment of human HSC in non-irradiated newborn NOD-scid IL2rgammanull mice is enhanced by transgenic expression of membrane-bound human SCF.. In: . . MGI: J:180273
Brem-Exner BG; Sattler C; Hutchinson JA; Koehl GE; Kronenberg K; Farkas S; Inoue S; Blank C; Knechtle SJ; Schlitt HJ; Fandrich F; Geissler EK. 2008. Macrophages driven to a novel state of activation have anti-inflammatory properties in mice.. In: . . MGI: J:130932
Bridgett M; Cetkovic-Cvrlje M; O'Rourke R; Shi Y; Narayanswami S; Lambert J; Ramiya V; Baekkeskov S; Leiter EH. 1998. Differential protection in two transgenic lines of NOD/Lt mice hyperexpressing the autoantigen GAD65 in pancreatic beta-cells.. In: . . MGI: J:100251
Browning JL; Allaire N; Ngam-Ek A; Notidis E; Hunt J; Perrin S; Fava RA. 2005. Lymphotoxin-beta receptor signaling is required for the homeostatic control of HEV differentiation and function.. In: . . MGI: J:113284
Bruedigam C; Bagger FO; Heidel FH; Paine Kuhn C; Guignes S; Song A; Austin R; Vu T; Lee E; Riyat S; Moore AS; Lock RB; Bullinger L; Hill GR; Armstrong SA; Williams DA; Lane SW. 2014. Telomerase inhibition effectively targets mouse and human AML stem cells and delays relapse following chemotherapy.. In: . . MGI: J:223853
Bueno C; Lopes LF; Greaves M; Menendez P. 2007. Toward development of a novel NOD/SCID-based in vivo strategy to model multiple myeloma pathogenesis.. In: . . MGI: J:126691
Bugl S; Wirths S; Radsak MP; Schild H; Stein P; Andre MC; Muller MR; Malenke E; Wiesner T; Marklin M; Frick JS; Handgretinger R; Rammensee HG; Kanz L; Kopp HG. 2013. Steady-state neutrophil homeostasis is dependent on TLR4/TRIF signaling.. In: . . MGI: J:194620
Bumgardner GL; Gao D; Li J; Baskin JH; Heininger M; Orosz CG. 2000. Rejection responses to allogeneic hepatocytes by reconstituted SCID mice, CD4, KO, and CD8 KO mice.. In: . . MGI: J:66571
Buning J; Schmitz M; Repenning B; Ludwig D; Schmidt MA; Strobel S; Zimmer KP. 2005. Interferon-gamma mediates antigen trafficking to MHC class II-positive late endosomes of enterocytes.. In: . . MGI: J:96737
Burdeinick-Kerr R; Wind J; Griffin DE. 2007. Synergistic roles of antibody and interferon in noncytolytic clearance of Sindbis virus from different regions of the central nervous system.. In: . . MGI: J:153321
Burke SD; Barrette VF; Carter AL; Gravel J; Adams MA; Croy BA. 2011. Cardiovascular adaptations of pregnancy in T and B cell-deficient mice.. In: . . MGI: J:176701
Burr KL; Smith AG; Dubrova YE. 2005. p53 deficiency does not affect mutation rate in the mouse germline.. In: . . MGI: J:99550
Butler JM; Nolan DJ; Vertes EL; Varnum-Finney B; Kobayashi H; Hooper AT; Seandel M; Shido K; White IA; Kobayashi M; Witte L; May C; Shawber C; Kimura Y; Kitajewski J; Rosenwaks Z; Bernstein ID; Rafii S. 2010. Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells.. In: . . MGI: J:158983
Calderon B; Suri A; Unanue ER. 2006. In CD4+ T-cell-induced diabetes, macrophages are the final effector cells that mediate islet beta-cell killing: studies from an acute model.. In: . . MGI: J:116218
Callen E; Jankovic M; Wong N; Zha S; Chen HT; Difilippantonio S; Di Virgilio M; Heidkamp G; Alt FW; Nussenzweig A; Nussenzweig M. 2009. Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes.. In: . . MGI: J:150435
Carrero JA; Calderon B; Unanue ER. 2006. Lymphocytes are detrimental during the early innate immune response against Listeria monocytogenes.. In: . . MGI: J:123753
Carter CR; Whitcomb JP; Campbell JA; Mukbel RM; McDowell MA. 2009. Complement receptor 3 deficiency influences lesion progression during Leishmania major infection in BALB/c mice.. In: . . MGI: J:155481
Chakraborty P; Buaas FW; Sharma M; Snyder E; de Rooij DG; Braun RE. 2014. LIN28A marks the spermatogonial progenitor population and regulates its cyclic expansion.. In: . . MGI: J:210438
Chang Y; Bosma GC; Bosma MJ. 1995. Development of B cells in scid mice with immunoglobulin transgenes: implications for the control of V(D)J recombination.. In: . . MGI: J:27341
Chang Y; Bosma MJ. 1997. Effect of different Ig transgenes on B cell differentiation in scid mice.. In: . . MGI: J:125479
Chaparro RJ; Konigshofer Y; Beilhack GF; Shizuru JA; McDevitt HO; Chien YH. 2006. Nonobese diabetic mice express aspects of both type 1 and type 2 diabetes.. In: . . MGI: J:111775
Chen AM; Zhou Y; Swenson K; Sachs DH; Sykes M; Yang YG. 2000. Porcine stem cell engraftment and seeding of murine thymus with class II+ cells in mice expressing porcine cytokines: toward tolerance induction across discordant xenogeneic barriers.. In: . . MGI: J:93486
Chen CC; Murray PJ; Jiang TX; Plikus MV; Chang YT; Lee OK; Widelitz RB; Chuong CM. 2014. Regenerative hair waves in aging mice and extra-follicular modulators follistatin, dkk1, and sfrp4.. In: . . MGI: J:212840
Chen CH; Yeh YC; Wu GJ; Huang YH; Lai WF; Liu JY; Tzeng CR. 2010. Tracking the rejection and survival of mouse ovarian iso- and allografts in vivo with bioluminescent imaging.. In: . . MGI: J:175817
Chen D; Pacal M; Wenzel P; Knoepfler PS; Leone G; Bremner R. 2009. Division and apoptosis of E2f-deficient retinal progenitors.. In: . . MGI: J:155800
Chen G; Han G; Wang J; Wang R; Xu R; Shen B; Qian J; Li Y. 2009. Natural killer cells modulate overt autoimmunity to homeostasis in nonobese diabetic mice after anti-CD3 F(ab')2 antibody treatment through secreting transforming growth factor-beta.. In: . . MGI: J:152908
Chen J; Chen YG; Reifsnyder PC; Schott WH; Lee CH; Osborne M; Scheuplein F; Haag F; Koch-Nolte F; Serreze DV; Leiter EH. 2006. Targeted disruption of CD38 accelerates autoimmune diabetes in NOD/Lt mice by enhancing autoimmunity in an ADP-ribosyltransferase 2-dependent fashion.. In: . . MGI: J:108097
Chen J; Gusdon AM; Piganelli J; Leiter EH; Mathews CE. 2011. mt-Nd2(a) Modifies resistance against autoimmune type 1 diabetes in NOD mice at the level of the pancreatic beta-cell.. In: . . MGI: J:170153
Chen Q; Amaladoss A; Ye W; Liu M; Dummler S; Kong F; Wong LH; Loo HL; Loh E; Tan SQ; Tan TC; Chang KT; Dao M; Suresh S; Preiser PR; Chen J. 2014. Human natural killer cells control Plasmodium falciparum infection by eliminating infected red blood cells.. In: . . MGI: J:206650
Chen YT; Chen FY; Vijmasi T; Stephens DN; Gallup M; McNamara NA. 2013. Pax6 downregulation mediates abnormal lineage commitment of the ocular surface epithelium in aqueous-deficient dry eye disease.. In: . . MGI: J:209118
Chen Z; Zhang Y; Jia C; Wang Y; Lai P; Zhou X; Wang Y; Song Q; Lin J; Ren Z; Gao Q; Zhao Z; Zheng H; Wan Z; Gao T; Zhao A; Dai Y; Bai X. 2014. mTORC1/2 targeted by n-3 polyunsaturated fatty acids in the prevention of mammary tumorigenesis and tumor progression.. In: . . MGI: J:214352
Cheung KJ; Padmanaban V; Silvestri V; Schipper K; Cohen JD; Fairchild AN; Gorin MA; Verdone JE; Pienta KJ; Bader JS; Ewald AJ. 2016. Polyclonal breast cancer metastases arise from collective dissemination of keratin 14-expressing tumor cell clusters.. In: . . MGI: J:230438
Chi X; Zhi L; Gelderman MP; Vostal JG. 2012. Host platelets and, in part, neutrophils mediate lung accumulation of transfused UVB-irradiated human platelets in a mouse model of acute lung injury.. In: . . MGI: J:191794
Chiang EY; Stroynowski I. 2004. A nonclassical MHC class I molecule restricts CTL-mediated rejection of a syngeneic melanoma tumor.. In: . . MGI: J:93729
Chiaraviglio L; Duong S; Brown DA; Birtles RJ; Kirby JE. 2010. An immunocompromised murine model of chronic Bartonella infection.. In: . . MGI: J:161161
Chirieleison SM; Feduska JM; Schugar RC; Askew Y; Deasy BM. 2012. Human muscle-derived cell populations isolated by differential adhesion rates: phenotype and contribution to skeletal muscle regeneration in Mdx/SCID mice.. In: . . MGI: J:181239
Chiu IM; Heesters BA; Ghasemlou N; Von Hehn CA; Zhao F; Tran J; Wainger B; Strominger A; Muralidharan S; Horswill AR; Bubeck Wardenburg J; Hwang SW; Carroll MC; Woolf CJ. 2013. Bacteria activate sensory neurons that modulate pain and inflammation.. In: . . MGI: J:205431
Choi B; Chun E; Kim M; Kim SY; Kim ST; Yoon K; Lee KY; Kim SJ. 2011. Human T cell development in the liver of humanized NOD/SCID/IL-2Rgamma(null)(NSG) mice generated by intrahepatic injection of CD34(+) human (h) cord blood (CB) cells.. In: . . MGI: J:173961
Choi S; Chen Z; Tang LH; Fang Y; Shin SJ; Panarelli NC; Chen YT; Li Y; Jiang X; Du YC. 2016. Bcl-xL promotes metastasis independent of its anti-apoptotic activity.. In: . . MGI: J:235886
Chou FC; Shieh SJ; Sytwu HK. 2009. Attenuation of Th1 response through galectin-9 and T-cell Ig mucin 3 interaction inhibits autoimmune diabetes in NOD mice.. In: . . MGI: J:152168
Chow LH. 1993. Studies of virus-induced myocardial injury in mice: value of the scid mutation on different genetic backgrounds and combined with other mutations.. In: . . MGI: J:12476
Christianson SW; Greiner DL; Hesselton RA; Leif JH; Wagar EJ; Schweitzer IB; Rajan TV; Gott B; Roopenian DC; Shultz LD. 1997. Enhanced human CD4+ T cell engraftment in beta2-microglobulin-deficient NOD-scid mice.. In: . . MGI: J:102141
Christianson SW; Greiner DL; Schweitzer IB; Gott B; Beamer GL; Schweitzer PA; Hesselton RM; Shultz LD. 1996. Role of natural killer cells on engraftment of human lymphoid cells and on metastasis of human T-lymphoblastoid leukemia cells in C57BL/6J-scid mice and in C57BL/6J-scid bg mice.. In: . . MGI: J:34814
Clark CA; Gupta HB; Sareddy G; Pandeswara S; Lao S; Yuan B; Drerup JM; Padron A; Conejo-Garcia J; Murthy K; Liu Y; Turk MJ; Thedieck K; Hurez V; Li R; Vadlamudi R; Curiel TJ. 2016. Tumor-Intrinsic PD-L1 Signals Regulate Cell Growth, Pathogenesis, and Autophagy in Ovarian Cancer and Melanoma.. In: . . MGI: J:237848
Clemente-Casares X; Blanco J; Ambalavanan P; Yamanouchi J; Singha S; Fandos C; Tsai S; Wang J; Garabatos N; Izquierdo C; Agrawal S; Keough MB; Yong VW; James E; Moore A; Yang Y; Stratmann T; Serra P; Santamaria P. 2016. Expanding antigen-specific regulatory networks to treat autoimmunity.. In: . . MGI: J:229667
Cleveland SM; Smith S; Tripathi R; Mathias EM; Goodings C; Elliott N; Peng D; El-Rifai W; Yi D; Chen X; Li L; Mullighan C; Downing JR; Love P; Dave UP. 2013. Lmo2 induces hematopoietic stem cell-like features in T-cell progenitor cells prior to leukemia.. In: . . MGI: J:196312
Cook AJ; Oganesian L; Harumal P; Basten A; Brink R; Jolly CJ. 2003. Reduced switching in SCID B cells is associated with altered somatic mutation of recombined S regions.. In: . . MGI: J:117994
Coombes JL; Siddiqui KR; Arancibia-Carcamo CV; Hall J; Sun CM; Belkaid Y; Powrie F. 2007. A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-beta and retinoic acid-dependent mechanism.. In: . . MGI: J:203901
Coppola V; Barrick CA; Southon EA; Celeste A; Wang K; Chen B; Haddad el-B; Yin J; Nussenzweig A; Subramaniam A; Tessarollo L. 2004. Ablation of TrkA function in the immune system causes B cell abnormalities.. In: . . MGI: J:93578
Cosgun KN; Rahmig S; Mende N; Reinke S; Hauber I; Schafer C; Petzold A; Weisbach H; Heidkamp G; Purbojo A; Cesnjevar R; Platz A; Bornhauser M; Schmitz M; Dudziak D; Hauber J; Kirberg J; Waskow C. 2014. Kit regulates HSC engraftment across the human-mouse species barrier.. In: . . MGI: J:232320
Covassin L; Jangalwe S; Jouvet N; Laning J; Burzenski L; Shultz LD; Brehm MA. 2013. Human immune system development and survival of NOD-scid IL2rgamma (NSG) mice engrafted with human thymus and autologous hematopoietic stem cells.. In: . . MGI: J:200896
Covassin L; Laning J; Abdi R; Langevin DL; Phillips NE; Shultz LD; Brehm MA. 2011. Human peripheral blood CD4 T cell-engrafted non-obese diabetic-scid IL2rgamma(null) H2-Ab1 (tm1Gru) Tg (human leucocyte antigen D-related 4) mice: a mouse model of human allogeneic graft-versus-host disease.. In: . . MGI: J:177904
Craven AJ; Nixon AJ; Ashby MG; Ormandy CJ; Blazek K; Wilkins RJ; Pearson AJ. 2006. Prolactin delays hair regrowth in mice.. In: . . MGI: J:114701
Crowe MJ; Doetschman T; Greenhalgh DG. 2000. Delayed wound healing in immunodeficient TGF-beta1 knockout mice. In: . . MGI: J:63260
Crowley SD; Song YS; Lin EE; Griffiths R; Kim HS; Ruiz P. 2010. Lymphocyte responses exacerbate angiotensin II-dependent hypertension.. In: . . MGI: J:158609
Culmsee C; Bondada S; Mattson MP. 2001. Hippocampal neurons of mice deficient in DNA-dependent protein kinase exhibit increased vulnerability to DNA damage, oxidative stress and excitotoxicity.. In: . . MGI: J:109293
Cupedo T; Lund FE; Ngo VN; Randall TD; Jansen W; Greuter MJ; de Waal-Malefyt R; Kraal G; Cyster JG; Mebius RE. 2004. Initiation of cellular organization in lymph nodes is regulated by non-B cell-derived signals and is not dependent on CXC chemokine ligand 13.. In: . . MGI: J:93711
Custer RP; Bosma GC; Bosma MJ. 1985. Severe combined immunodeficiency (SCID) in the mouse. Pathology, reconstitution, neoplasms.. In: . . MGI: J:30980
D'Aveni M; Rossignol J; Coman T; Sivakumaran S; Henderson S; Manzo T; Santos e Sousa P; Bruneau J; Fouquet G; Zavala F; Alegria-Prevot O; Garfa-Traore M; Suarez F; Trebeden-Negre H; Mohty M; Bennett CL; Chakraverty R; Hermine O; Rubio MT. 2015. G-CSF mobilizes CD34+ regulatory monocytes that inhibit graft-versus-host disease.. In: . . MGI: J:234081
Dann SM; Spehlmann ME; Hammond DC; Iimura M; Hase K; Choi LJ; Hanson E; Eckmann L. 2008. IL-6-dependent mucosal protection prevents establishment of a microbial niche for attaching/effacing lesion-forming enteric bacterial pathogens.. In: . . MGI: J:134871
Danska JS; Holland DP; Mariathasan S; Williams KM; Guidos CJ. 1996. Biochemical and genetic defects in the DNA-dependent protein kinase in murine scid lymphocytes.. In: . . MGI: J:35350
Darwiche R; Chong MM; Santamaria P; Thomas HE; Kay TW. 2003. Fas is detectable on beta cells in accelerated, but not spontaneous, diabetes in nonobese diabetic mice.. In: . . MGI: J:108698
Das R; Bassiri H; Guan P; Wiener S; Banerjee PP; Zhong MC; Veillette A; Orange JS; Nichols KE. 2013. The adaptor molecule SAP plays essential roles during invariant NKT cell cytotoxicity and lytic synapse formation.. In: . . MGI: J:196692
De Luca A; Carvalho A; Cunha C; Iannitti RG; Pitzurra L; Giovannini G; Mencacci A; Bartolommei L; Moretti S; Massi-Benedetti C; Fuchs D; De Bernardis F; Puccetti P; Romani L. 2013. IL-22 and IDO1 affect immunity and tolerance to murine and human vaginal candidiasis.. In: . . MGI: J:213365
De Palma M; Venneri MA; Galli R; Sergi LS; Politi LS; Sampaolesi M; Naldini L. 2005. Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors.. In: . . MGI: J:102241
Derecki NC; Cardani AN; Yang CH; Quinnies KM; Crihfield A; Lynch KR; Kipnis J. 2010. Regulation of learning and memory by meningeal immunity: a key role for IL-4.. In: . . MGI: J:160932
DiLorenzo TP; Lieberman SM; Takaki T; Honda S; Chapman HD; Santamaria P; Serreze DV; Nathenson SG. 2002. During the early prediabetic period in NOD mice, the pathogenic CD8(+) T-cell population comprises multiple antigenic specificities.. In: . . MGI: J:94192
Diamond RA; Ward SB; Owada-Makabe K; Wang H; Rothenberg EV. 1997. Different developmental arrest points in RAG-2 -/- and SCID thymocytes on two genetic backgrounds: developmental choices and cell death mechanisms before TCR gene rearrangement.. In: . . MGI: J:39793
Diaz-Manera J; Touvier T; Dellavalle A; Tonlorenzi R; Tedesco FS; Messina G; Meregalli M; Navarro C; Perani L; Bonfanti C; Illa I; Torrente Y; Cossu G. 2010. Partial dysferlin reconstitution by adult murine mesoangioblasts is sufficient for full functional recovery in a murine model of dysferlinopathy.. In: . . MGI: J:186461
Dibra D; Cutrera JJ; Li S. 2012. Coordination between TLR9 signaling in macrophages and CD3 signaling in T cells induces robust expression of IL-30.. In: . . MGI: J:184078
Dodig TD; Mack KT; Cassarino DF; Clark SH. 2001. Development of the tight-skin phenotype in immune-deficient mice.. In: . . MGI: J:112962
Doherty TM; Sher A. 1997. Defects in cell-mediated immunity affect chronic, but not innate, resistance of mice to Mycobacterium avium infection.. In: . . MGI: J:40202
Dohi T; Fujihashi K; Koga T; Etani Y; Yoshino N; Kawamura YI; McGhee JR. 2004. CD4+CD45RBHi interleukin-4 defective T cells elicit antral gastritis and duodenitis.. In: . . MGI: J:93676
Dohi T; Fujihashi K; Koga T; Shirai Y; Kawamura YI; Ejima C; Kato R; Saitoh K; McGhee JR. 2003. T helper type-2 cells induce ileal villus atrophy, goblet cell metaplasia, and wasting disease in T cell-deficient mice.. In: . . MGI: J:82106
Dominique V; Francis L. 1995. Interactions of the scid or beige mutations with the viable motheaten mutation.. In: . . MGI: J:33985
Dorshkind K; Keller GM; Phillips RA; Miller RG; Bosma GC; O'Toole M; Bosma MJ. 1984. Functional status of cells from lymphoid and myeloid tissues in mice with severe combined immunodeficiency disease.. In: . . MGI: J:7343
Dos Santos C; McDonald T; Ho YW; Liu H; Lin A; Forman SJ; Kuo YH; Bhatia R. 2013. The Src and c-Kit kinase inhibitor dasatinib enhances p53-mediated targeting of human acute myeloid leukemia stem cells by chemotherapeutic agents.. In: . . MGI: J:202360
Dreyer AM; Matile H; Papastogiannidis P; Kamber J; Favuzza P; Voss TS; Wittlin S; Pluschke G. 2012. Passive immunoprotection of Plasmodium falciparum-infected mice designates the CyRPA as candidate malaria vaccine antigen.. In: . . MGI: J:188965
Dudek NL; Thomas HE; Mariana L; Sutherland RM; Allison J; Estella E; Angstetra E; Trapani JA; Santamaria P; Lew AM; Kay TW. 2006. Cytotoxic T-cells from T-cell receptor transgenic NOD8.3 mice destroy beta-cells via the perforin and Fas pathways.. In: . . MGI: J:116592
Dudley ME; Sundberg JP; Roopenian DC. 1996. Frequency and histological appearance of adenomas in multiple intestinal neoplasia mice are unaffected by severe combined immunodeficiency (scid) mutation.. In: . . MGI: J:31690
Dullin C; Missbach-Guentner J; Vogel WF; Grabbe E; Alves F. 2007. Semi-Automatic Classification of Skeletal Morphology in Genetically Altered Mice Using Flat-Panel Volume Computed Tomography.. In: . . MGI: J:123719
Dumont N; Boyer L; Emond H; Celebi-Saltik B; Pasha R; Bazin R; Mantovani D; Roy DC; Pineault N. 2014. Medium conditioned with mesenchymal stromal cell-derived osteoblasts improves the expansion and engraftment properties of cord blood progenitors.. In: . . MGI: J:214003
Eaton KA; Benson LH; Haeger J; Gray BM. 2006. Role of transcription factor T-bet expression by CD4+ cells in gastritis due to Helicobacter pylori in mice.. In: . . MGI: J:112403
Eaton KA; Mefford M; Thevenot T. 2001. The role of T cell subsets and cytokines in the pathogenesis of Helicobacter pylori gastritis in mice.. In: . . MGI: J:124425
Ebrahem Q; Chaurasia SS; Vasanji A; Qi JH; Klenotic PA; Cutler A; Asosingh K; Erzurum S; Anand-Apte B. 2010. Cross-talk between vascular endothelial growth factor and matrix metalloproteinases in the induction of neovascularization in vivo.. In: . . MGI: J:156380
Economopoulos V; Noad JC; Krishnamoorthy S; Rutt BK; Foster PJ. 2011. Comparing the MRI appearance of the lymph nodes and spleen in wild-type and immuno-deficient mouse strains.. In: . . MGI: J:180968
Elsegeiny W; Eddens T; Chen K; Kolls JK. 2015. Anti-CD20 antibody therapy and susceptibility to Pneumocystis pneumonia.. In: . . MGI: J:229720
Emoto M; Mittrucker HW; Schmits R; Mak TW; Kaufmann SH. 1999. Critical role of leukocyte function-associated antigen-1 in liver accumulation of CD4+NKT cells.. In: . . MGI: J:111009
Engle SJ; Ormsby I; Pawlowski S; Boivin GP; Croft J; Balish E; Doetschman T. 2002. Elimination of Colon Cancer in Germ-free Transforming Growth Factor Beta 1-deficient Mice.. In: . . MGI: J:80209
English WR; Lunt SJ; Fisher M; Lefley DV; Dhingra M; Lee YC; Bingham K; Hurrell JE; Lyons SK; Kanthou C; Tozer GM. 2017. Differential Expression of VEGFA Isoforms Regulates Metastasis and Response to Anti-VEGFA Therapy in Sarcoma.. In: . . MGI: J:242299
Ernst PB; Erickson LD; Loo WM; Scott KG; Wiznerowicz EB; Brown CC; Torres-Velez FJ; Alam MS; Black SG; McDuffie M; Feldman SH; Wallace JL; McKnight GW; Padol IT; Hunt RH; Tung KS. 2012. Spontaneous autoimmune gastritis and hypochlorhydria are manifest in the ileitis-prone SAMP1/YitFcs mice.. In: . . MGI: J:183342
Eyob H; Ekiz HA; Derose YS; Waltz SE; Williams MA; Welm AL. 2013. Inhibition of ron kinase blocks conversion of micrometastases to overt metastases by boosting antitumor immunity.. In: . . MGI: J:203569
Fahlen L; Read S; Gorelik L; Hurst SD; Coffman RL; Flavell RA; Powrie F. 2005. T cells that cannot respond to TGF-{beta} escape control by CD4+CD25+ regulatory T cells.. In: . . MGI: J:96624
Faleo G; Fotino C; Bocca N; Molano RD; Zahr-Akrawi E; Molina J; Villate S; Umland O; Skyler JS; Bayer AL; Ricordi C; Pileggi A. 2012. Prevention of autoimmune diabetes and induction of beta-cell proliferation in NOD mice by hyperbaric oxygen therapy.. In: . . MGI: J:203601
Fang R; Ismail N; Walker DH. 2012. Contribution of NK cells to the innate phase of host protection against an intracellular bacterium targeting systemic endothelium.. In: . . MGI: J:185539
Farini A; Meregalli M; Belicchi M; Battistelli M; Parolini D; D'Antona G; Gavina M; Ottoboni L; Constantin G; Bottinelli R; Torrente Y. 2007. T and B lymphocyte depletion has a marked effect on the fibrosis of dystrophic skeletal muscles in the scid/mdx mouse.. In: . . MGI: J:125527
Farini A; Sitzia C; Navarro C; D'Antona G; Belicchi M; Parolini D; Del Fraro G; Razini P; Bottinelli R; Meregalli M; Torrente Y. 2012. Absence of T and B lymphocytes modulates dystrophic features in dysferlin deficient animal model.. In: . . MGI: J:186460
Fattahi F; Steinbeck JA; Kriks S; Tchieu J; Zimmer B; Kishinevsky S; Zeltner N; Mica Y; El-Nachef W; Zhao H; de Stanchina E; Gershon MD; Grikscheit TC; Chen S; Studer L. 2016. Deriving human ENS lineages for cell therapy and drug discovery in Hirschsprung disease.. In: . . MGI: J:229669
Feng M; Chen JY; Weissman-Tsukamoto R; Volkmer JP; Ho PY; McKenna KM; Cheshier S; Zhang M; Guo N; Gip P; Mitra SS; Weissman IL. 2015. Macrophages eat cancer cells using their own calreticulin as a guide: roles of TLR and Btk.. In: . . MGI: J:220007
Fernandez NC; Lozier A; Flament C; Ricciardi-Castagnoli P; Bellet D; Suter M; Perricaudet M; Tursz T; Maraskovsky E; Zitvogel L. 1999. Dendritic cells directly trigger NK cell functions: cross-talk relevant in innate anti-tumor immune responses in vivo.. In: . . MGI: J:54135
Fiorucci S; Mencarelli A; Palazzetti B; Sprague AG; Distrutti E; Morelli A; Novobrantseva TI; Cirino G; Koteliansky VE; de Fougerolles AR. 2002. Importance of innate immunity and collagen binding integrin alpha1beta1 in TNBS-induced colitis.. In: . . MGI: J:113581
Flanagan K; Modrusan Z; Cornelius J; Chavali A; Kasman I; Komuves L; Mo L; Diehl L. 2008. Intestinal Epithelial Cell Up-Regulation of LY6 Molecules during Colitis Results in Enhanced Chemokine Secretion.. In: . . MGI: J:133031
Flesken-Nikitin A; Hwang CI; Cheng CY; Michurina TV; Enikolopov G; Nikitin AY. 2013. Ovarian surface epithelium at the junction area contains a cancer-prone stem cell niche.. In: . . MGI: J:194916
Fogler WE; Volker K; Watanabe M; Wigginton JM; Roessler P; Brunda MJ; Ortaldo JR; Wiltrout RH. 1998. Recruitment of hepatic NK cells by IL-12 is dependent on IFN-gamma and VCAM-1 and is rapidly down-regulated by a mechanism involving T cells and expression of Fas.. In: . . MGI: J:115033
Foquet L; Hermsen CC; van Gemert GJ; Van Braeckel E; Weening KE; Sauerwein R; Meuleman P; Leroux-Roels G. 2014. Vaccine-induced monoclonal antibodies targeting circumsporozoite protein prevent Plasmodium falciparum infection.. In: . . MGI: J:207925
Forbes JM; Soderlund J; Yap FY; Knip M; Andrikopoulos S; Ilonen J; Simell O; Veijola R; Sourris KC; Coughlan MT; Forsblom C; Slattery R; Grey ST; Wessman M; Yamamoto H; Bierhaus A; Cooper ME; Groop PH. 2011. Receptor for advanced glycation end-products (RAGE) provides a link between genetic susceptibility and environmental factors in type 1 diabetes.. In: . . MGI: J:169600
Ford ML; Evavold BD. 2006. Modulation of MOG 37-50-specific CD8+ T cell activation and expansion by CD43.. In: . . MGI: J:112761
Fortner KA; Lees RK; Macdonald HR; Budd RC. 2011. Fas (CD95/APO-1) limits the expansion of T lymphocytes in an environment of limited T-cell antigen receptor/MHC contacts.. In: . . MGI: J:168554
Fournier B; Murray B; Gutzwiller S; Marcaletti S; Marcellin D; Bergling S; Brachat S; Persohn E; Pierrel E; Bombard F; Hatakeyama S; Trendelenburg AU; Morvan F; Richardson B; Glass DJ; Lach-Trifilieff E; Feige JN. 2012. Blockade of the activin receptor IIb activates functional brown adipogenesis and thermogenesis by inducing mitochondrial oxidative metabolism.. In: . . MGI: J:186659
Franco S; Murphy MM; Li G; Borjeson T; Boboila C; Alt FW. 2008. DNA-PKcs and Artemis function in the end-joining phase of immunoglobulin heavy chain class switch recombination.. In: . . MGI: J:133132
Frese M; Lee E; Larena M; Lim PS; Rao S; Matthaei KI; Khromykh A; Ramshaw I; Lobigs M. 2014. Internal ribosome entry site-based attenuation of a flavivirus candidate vaccine and evaluation of the effect of Beta interferon coexpression on vaccine properties.. In: . . MGI: J:205265
Friedline RH; Ko HJ; Jung DY; Lee Y; Bortell R; Dagdeviren S; Patel PR; Hu X; Inashima K; Kearns C; Tsitsilianos N; Shafiq U; Shultz LD; Lee KW; Greiner DL; Kim JK. 2016. Genetic ablation of lymphocytes and cytokine signaling in nonobese diabetic mice prevents diet-induced obesity and insulin resistance.. In: . . MGI: J:230896
Friswell MK; Gika H; Stratford IJ; Theodoridis G; Telfer B; Wilson ID; McBain AJ. 2010. Site and strain-specific variation in gut microbiota profiles and metabolism in experimental mice.. In: . . MGI: J:157249
Fuentes RE; Zaitsev S; Ahn HS; Hayes V; Kowalska MA; Lambert MP; Wang Y; Siegel DL; Bougie DW; Aster RH; Myers DD; Stepanova V; Cines DB; Muzykantov VR; Poncz M. 2015. A chimeric platelet-targeted urokinase prodrug selectively blocks new thrombus formation.. In: . . MGI: J:231183
Fukunaga-Kalabis M; Martinez G; Nguyen TK; Kim D; Santiago-Walker A; Roesch A; Herlyn M. 2010. Tenascin-C promotes melanoma progression by maintaining the ABCB5-positive side population.. In: . . MGI: J:166563
Fulop GM; Phillips RA. 1986. Full reconstitution of the immune deficiency in scid mice with normal stem cells requires low-dose irradiation of the recipients.. In: . . MGI: J:8299
Fyfe AI; Qiao JH; Lusis AJ. 1994. Immune-deficient mice develop typical atherosclerotic fatty streaks when fed an atherogenic diet.. In: . . MGI: J:22138
Gallo-Hendrikx E; Percy D; Copps J; McKeown B; Quinton M; McMillan I; Croy BA; Wildeman AG. 1999. Evaluation of three lines of immunodeficient mice for the study of spontaneous metastatic tumors.. In: . . MGI: J:54114
Ganley L; Babu S; Rajan TV. 2001. Course of Brugia malayi infection in C57BL/6J NOS2 +/+ and -/- mice.. In: . . MGI: J:102684
Garcia-Barros M; Thin TH; Maj J; Cordon-Cardo C; Haimovitz-Friedman A; Fuks Z; Kolesnick R. 2010. Impact of stromal sensitivity on radiation response of tumors implanted in SCID hosts revisited.. In: . . MGI: J:165564
Garcia-Rivera MF; Colvin-Wanshura LE; Nelson MS; Nan Z; Khan SA; Rogers TB; Maitra I; Low WC; Gupta P. 2007. Characterization of an immunodeficient mouse model of mucopolysaccharidosis type I suitable for preclinical testing of human stem cell and gene therapy.. In: . . MGI: J:139626
Gawronska-Kozak B; Bogacki M; Rim JS; Monroe WT; Manuel JA. 2006. Scarless skin repair in immunodeficient mice.. In: . . MGI: J:135709
Gelman AE; LaRosa DF; Zhang J; Walsh PT; Choi Y; Sunyer JO; Turka LA. 2006. The adaptor molecule MyD88 activates PI-3 kinase signaling in CD4+ T cells and enables CpG oligodeoxynucleotide-mediated costimulation.. In: . . MGI: J:116106
Gerling IC; Friedman H; Greiner DL; Shultz LD; Leiter EH. 1994. Multiple low-dose streptozocin-induced diabetes in NOD-scid/scid mice in the absence of functional lymphocytes.. In: . . MGI: J:16998
Gesina E; Blondeau B; Milet A; Le Nin I; Duchene B; Czernichow P; Scharfmann R; Tronche F; Breant B. 2006. Glucocorticoid signalling affects pancreatic development through both direct and indirect effects.. In: . . MGI: J:147261
Gittens JE; Barr KJ; Vanderhyden BC; Kidder GM. 2005. Interplay between paracrine signaling and gap junctional communication in ovarian follicles.. In: . . MGI: J:94692
Gladdy RA; Nutter LM; Kunath T; Danska JS; Guidos CJ. 2006. p53-Independent apoptosis disrupts early organogenesis in embryos lacking both ataxia-telangiectasia mutated and Prkdc.. In: . . MGI: J:108789
Gladdy RA; Taylor MD; Williams CJ; Grandal I; Karaskova J; Squire JA; Rutka JT; Guidos CJ; Danska JS. 2003. The RAG-1/2 endonuclease causes genomic instability and controls CNS complications of lymphoblastic leukemia in p53/Prkdc-deficient mice.. In: . . MGI: J:81538
Glimm H; Eisterer W; Lee K; Cashman J; Holyoake TL; Nicolini F; Shultz LD; von Kalle C; Eaves CJ. 2001. Previously undetected human hematopoietic cell populations with short-term repopulating activity selectively engraft NOD/SCID-beta2 microglobulin-null mice.. In: . . MGI: J:66974
Goldstein AS; Huang J; Guo C; Garraway IP; Witte ON. 2010. Identification of a cell of origin for human prostate cancer.. In: . . MGI: J:162606
Gorantla S; Makarov E; Finke-Dwyer J; Gebhart CL; Domm W; Dewhurst S; Gendelman HE; Poluektova LY. 2010. CD8+ cell depletion accelerates HIV-1 immunopathology in humanized mice.. In: . . MGI: J:161304
Graff RJ. 1970. Polymorphism of histocompatibility genes in the mouse.. In: . . MGI: J:5237
Graser RT; DiLorenzo TP; Wang F; Christianson GJ; Chapman HD; Roopenian DC; Nathenson SG; Serreze DV. 2000. Identification of a CD8 T cell that can independently mediate autoimmune diabetes development in the complete absence of CD4 T cell helper functions.. In: . . MGI: J:93553
Gray CA; Lawrence RA. 2002. A role for antibody and Fc receptor in the clearance of Brugia malayi microfilariae.. In: . . MGI: J:115364
Green-Mitchell SM; Tersey SA; Cole BK; Ma K; Kuhn NS; Cunningham TD; Maybee NA; Chakrabarti SK; McDuffie M; Taylor-Fishwick DA; Mirmira RG; Nadler JL; Morris MA. 2013. Deletion of 12/15-lipoxygenase alters macrophage and islet function in NOD-Alox15(null) mice, leading to protection against type 1 diabetes development.. In: . . MGI: J:197192
Grenningloh R; Kang BY; Ho IC. 2005. Ets-1, a functional cofactor of T-bet, is essential for Th1 inflammatory responses.. In: . . MGI: J:96627
Griffin RL; Kupper TS; Divito SJ. 2015. Humanized Mice in Dermatology Research.. In: . . MGI: J:228055
Guay HM; Andreyeva TA; Garcea RL; Welsh RM; Szomolanyi-Tsuda E. 2007. MyD88 is required for the formation of long-term humoral immunity to virus infection.. In: . . MGI: J:145278
Guay HM; Panarey L; Reed AJ; Caton AJ. 2004. Specificity-based negative selection of autoreactive B cells during memory formation.. In: . . MGI: J:93744
Guidos CJ; Williams CJ; Grandal I; Knowles G; Huang MT; Danska JS. 1996. V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors.. In: . . MGI: J:102044
Gundry MC; Brunetti L; Lin A; Mayle AE; Kitano A; Wagner D; Hsu JI; Hoegenauer KA; Rooney CM; Goodell MA; Nakada D. 2016. Highly Efficient Genome Editing of Murine and Human Hematopoietic Progenitor Cells by CRISPR/Cas9.. In: . . MGI: J:240901
Gurley KE; Kemp CJ. 2001. Synthetic lethality between mutation in Atm and DNA-PK(cs) during murine embryogenesis.. In: . . MGI: J:67533
Gurley KE; Vo K; Kemp CJ. 1998. DNA double-strand breaks, p53, and apoptosis during lymphomagenesis in scid/scid mice.. In: . . MGI: J:49372
Haetscher N; Feuermann Y; Wingert S; Rehage M; Thalheimer FB; Weiser C; Bohnenberger H; Jung K; Schroeder T; Serve H; Oellerich T; Hennighausen L; Rieger MA. 2015. STAT5-regulated microRNA-193b controls haematopoietic stem and progenitor cell expansion by modulating cytokine receptor signalling.. In: . . MGI: J:228007
Haks MC; Belkowski SM; Ciofani M; Rhodes M; Lefebvre JM; Trop S; Hugo P; Zuniga-Pflucker JC; Wiest DL. 2003. Low activation threshold as a mechanism for ligand-independent signaling in pre-T cells.. In: . . MGI: J:126301
Haks MC; Krimpenfort P; van den Brakel JH; Kruisbeek AM. 1999. Pre-TCR signaling and inactivation of p53 induces crucial cell survival pathways in pre-T cells.. In: . . MGI: J:110456
Halim TY; Maclaren A; Romanish MT; Gold MJ; McNagny KM; Takei F. 2012. Retinoic-Acid-receptor-related orphan nuclear receptor alpha is required for natural helper cell development and allergic inflammation.. In: . . MGI: J:187662
Halin C; Tobler NE; Vigl B; Brown LF; Detmar M. 2007. VEGF-A produced by chronically inflamed tissue induces lymphangiogenesis in draining lymph nodes.. In: . . MGI: J:148904
Haller BL; Barkon ML; Vogler GP; Virgin HW 4th. 1995. Genetic mapping of reovirus virulence and organ tropism in severe combined immunodeficient mice: organ-specific virulence genes.. In: . . MGI: J:21933
Han D; Walsh MC; Cejas PJ; Dang NN; Kim YF; Kim J; Charrier-Hisamuddin L; Chau L; Zhang Q; Bittinger K; Bushman FD; Turka LA; Shen H; Reizis B; Defranco AL; Wu GD; Choi Y. 2013. Dendritic cell expression of the signaling molecule TRAF6 is critical for gut microbiota-dependent immune tolerance.. In: . . MGI: J:207581
Han SJ; Jung SY; Wu SP; Hawkins SM; Park MJ; Kyo S; Qin J; Lydon JP; Tsai SY; Tsai MJ; DeMayo FJ; O'Malley BW. 2015. Estrogen Receptor beta Modulates Apoptosis Complexes and the Inflammasome to Drive the Pathogenesis of Endometriosis.. In: . . MGI: J:228035
Hande P; Slijepcevic P; Silver A; Bouffler S; van Buul P; Bryant P ; Lansdorp P. 1999. Elongated telomeres in scid mice.. In: . . MGI: J:53579
Hanks BA; Holtzhausen A; Evans KS; Jamieson R; Gimpel P; Campbell OM; Hector-Greene M; Sun L; Tewari A; George A; Starr M; Nixon A; Augustine C; Beasley G; Tyler DS; Osada T; Morse MA; Ling L; Lyerly HK; Blobe GC. 2013. Type III TGF-beta receptor downregulation generates an immunotolerant tumor microenvironment.. In: . . MGI: J:201617
Harkness RE; Guimond MJ; McBey BA; Klein MH; Percy DH; Croy BA. 1993. Branhamella catarrhalis pathogenesis in SCID and SCID/beige mice. Brief report.. In: . . MGI: J:16050
Harris WJ; Huang X; Lynch JT; Spencer GJ; Hitchin JR; Li Y; Ciceri F; Blaser JG; Greystoke BF; Jordan AM; Miller CJ; Ogilvie DJ; Somervaille TC. 2012. The histone demethylase KDM1A sustains the oncogenic potential of MLL-AF9 leukemia stem cells.. In: . . MGI: J:189339
Hasegawa M; Kawai K; Mitsui T; Taniguchi K; Monnai M; Wakui M; Ito M; Suematsu M; Peltz G; Nakamura M; Suemizu H. 2011. The reconstituted 'humanized liver' in TK-NOG mice is mature and functional.. In: . . MGI: J:170638
Hastey CJ; Elsner RA; Barthold SW; Baumgarth N. 2012. Delays and diversions mark the development of B cell responses to Borrelia burgdorferi infection.. In: . . MGI: J:188726
Hayakawa Y; Sakitani K; Konishi M; Asfaha S; Niikura R; Tomita H; Renz BW; Tailor Y; Macchini M; Middelhoff M; Jiang Z; Tanaka T; Dubeykovskaya ZA; Kim W; Chen X; Urbanska AM; Nagar K; Westphalen CB; Quante M; Lin CS; Gershon MD; Hara A; Zhao CM; Chen D; Worthley DL; Koike K; Wang TC. 2017. Nerve Growth Factor Promotes Gastric Tumorigenesis through Aberrant Cholinergic Signaling.. In: . . MGI: J:238420
Hayashi Y; Haneji N; Hamano H; Yanagi K. 1994. Transfer of Sjogren's syndrome-like autoimmune lesions into SCID mice and prevention of lesions by anti-CD4 and anti-T cell receptor antibody treatment.. In: . . MGI: J:21965
Hayward AR; Chmura K; Cosyns M. 2000. Interferon-gamma is required for innate immunity to Cryptosporidium parvum in mice.. In: . . MGI: J:125986
He J; Haskins K. 2008. Pathogenicity of T helper 2 T-cell clones from T-cell receptor transgenic non-obese diabetic mice is determined by tumour necrosis factor-alpha.. In: . . MGI: J:134900
He Q; Morillon YM 2nd; Spidale NA; Kroger CJ; Liu B; Sartor RB; Wang B; Tisch R. 2013. Thymic development of autoreactive T cells in NOD mice is regulated in an age-dependent manner.. In: . . MGI: J:207147
Heaney NB; Pellicano F; Zhang B; Crawford L; Chu S; Kazmi SM; Allan EK; Jorgensen HG; Irvine AE; Bhatia R; Holyoake TL. 2010. Bortezomib induces apoptosis in primitive chronic myeloid leukemia cells including LTC-IC and NOD/SCID repopulating cells.. In: . . MGI: J:162612
Heine D; Passmore HC; Patel V; Shultz LD; Ward-Bailey P; Cook SA; Davisson MT. 1996. Effect of the mouse scid mutation on meiotic recombination.. In: . . MGI: J:34473
Hernandez-Novoa B; Bishop L; Logun C; Munson PJ; Elnekave E; Rangel ZG; Barb J; Danner RL; Kovacs JA. 2008. Immune responses to Pneumocystis murina are robust in healthy mice but largely absent in CD40 ligand-deficient mice.. In: . . MGI: J:138448
Hertz CJ; Filutowicz H; Mansfield JM. 1998. Resistance to the African trypanosomes is IFN-gamma dependent.. In: . . MGI: J:115095
Hesselton RM; Greiner DL; Mordes JP; Rajan TV; Sullivan JL; Shultz LD. 1995. High levels of human peripheral blood mononuclear cell engraftment and enhanced susceptibility to human immunodeficiency virus type 1 infection in NOD/LtSz-scid/scid mice.. In: . . MGI: J:109911
Hettmer S; Liu J; Miller CM; Lindsay MC; Sparks CA; Guertin DA; Bronson RT; Langenau DM; Wagers AJ. 2011. Sarcomas induced in discrete subsets of prospectively isolated skeletal muscle cells.. In: . . MGI: J:180528
Hilbert DM; Anderson AO; Holmes KL; Rudikoff S. 1994. Long-term lymphoid reconstitution of SCID mice suggests self-renewing B and T cell populations in peripheral and mucosal tissues.. In: . . MGI: J:19983
Hioki K; Kuramochi T; Endoh S; Terada E; Ueyama Y; Ito M. 2001. Lack of B cell leakiness in BALB/cA-nu, scid double mutant mice.. In: . . MGI: J:68089
Hirai H; Verma M; Watanabe S; Tastad C; Asakura Y; Asakura A. 2010. MyoD regulates apoptosis of myoblasts through microRNA-mediated down-regulation of Pax3.. In: . . MGI: J:165481
Hiramatsu H; Nishikomori R; Heike T; Ito M; Kobayashi K; Katamura K; Nakahata T. 2003. Complete reconstitution of human lymphocytes from cord blood CD34+ cells using the NOD/SCID/gammacnull mice model.. In: . . MGI: J:163372
Hofling AA; Vogler C; Creer MH; Sands MS. 2003. Engraftment of human CD34+ cells leads to widespread distribution of donor-derived cells and correction of tissue pathology in a novel murine xenotransplantation model of lysosomal storage disease.. In: . . MGI: J:109848
Hoggatt J; Singh P; Sampath J; Pelus LM. 2009. Prostaglandin E2 enhances hematopoietic stem cell homing, survival, and proliferation.. In: . . MGI: J:148898
Holland JD; Gyorffy B; Vogel R; Eckert K; Valenti G; Fang L; Lohneis P; Elezkurtaj S; Ziebold U; Birchmeier W. 2013. Combined Wnt/beta-catenin, Met, and CXCL12/CXCR4 signals characterize basal breast cancer and predict disease outcome.. In: . . MGI: J:206839
Holm TM; Jackson-Grusby L; Brambrink T; Yamada Y; Rideout WM 3rd; Jaenisch R. 2005. Global loss of imprinting leads to widespread tumorigenesis in adult mice.. In: . . MGI: J:104860
Holodick NE; Vizconde T; Rothstein TL. 2014. B-1a cell diversity: nontemplated addition in B-1a cell Ig is determined by progenitor population and developmental location.. In: . . MGI: J:209818
Holopainen T; Saharinen P; D'Amico G; Lampinen A; Eklund L; Sormunen R; Anisimov A; Zarkada G; Lohela M; Helotera H; Tammela T; Benjamin LE; Yla-Herttuala S; Leow CC; Koh GY; Alitalo K. 2012. Effects of angiopoietin-2-blocking antibody on endothelial cell-cell junctions and lung metastasis.. In: . . MGI: J:184937
Holt N; Wang J; Kim K; Friedman G; Wang X; Taupin V; Crooks GM; Kohn DB; Gregory PD; Holmes MC; Cannon PM. 2010. Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo.. In: . . MGI: J:162607
Hontecillas R; Bassaganya-Riera J. 2007. Peroxisome proliferator-activated receptor gamma is required for regulatory CD4+ T cell-mediated protection against colitis.. In: . . MGI: J:144105
Horai R; Nakajima A; Habiro K; Kotani M; Nakae S; Matsuki T; Nambu A; Saijo S; Kotaki H; Sudo K; Okahara A; Tanioka H; Ikuse T; Ishii N; Schwartzberg PL; Abe R; Iwakura Y. 2004. TNF-alpha is crucial for the development of autoimmune arthritis in IL-1 receptor antagonist-deficient mice.. In: . . MGI: J:94429
Hoshino T; Winkler-Pickett RT; Mason AT; Ortaldo JR; Young HA. 1999. IL-13 production by NK cells: IL-13-producing NK and T cells are present in vivo in the absence of IFN-gamma.. In: . . MGI: J:112424
Houghtaling S; Newell A; Akkari Y; Taniguchi T; Olson S; Grompe M. 2005. Fancd2 functions in a double strand break repair pathway that is distinct from non-homologous end joining.. In: . . MGI: J:102754
Hsu DM; Agarwal S; Benham A; Coarfa C; Trahan DN; Chen Z; Stowers PN; Courtney AN; Lakoma A; Barbieri E; Metelitsa LS; Gunaratne P; Kim ES; Shohet JM. 2013. G-CSF Receptor Positive Neuroblastoma Subpopulations Are Enriched in Chemotherapy-Resistant or Relapsed Tumors and Are Highly Tumorigenic.. In: . . MGI: J:199119
Hu Z; Van Rooijen N; Yang YG. 2011. Macrophages prevent human red blood cell reconstitution in immunodeficient mice.. In: . . MGI: J:178783
Hua C; Chang B; Ma B-L; Li Y; Wang G. 1992. Reduction of lymphokine-activated killer cell activity by the introduction of the beige gene into SCID mice. In: . . MGI: J:2627
Huang P; Huo Y; Lou LX; Li H; Barnstable CJ; Zhang C; Zhang SS. 2013. CD4 positive T helper cells contribute to retinal ganglion cell death in mouse model of ischemia reperfusion injury.. In: . . MGI: J:210412
Hubner A; Mulholland DJ; Standen CL; Karasarides M; Cavanagh-Kyros J; Barrett T; Chi H; Greiner DL; Tournier C; Sawyers CL; Flavell RA; Wu H; Davis RJ. 2012. JNK and PTEN cooperatively control the development of invasive adenocarcinoma of the prostate.. In: . . MGI: J:186492
Hubner MP; Shi Y; Torrero MN; Mueller E; Larson D; Soloviova K; Gondorf F; Hoerauf A; Killoran KE; Stocker JT; Davies SJ; Tarbell KV; Mitre E. 2012. Helminth protection against autoimmune diabetes in nonobese diabetic mice is independent of a type 2 immune shift and requires TGF-beta.. In: . . MGI: J:180789
Hugues S; Mougneau E; Ferlin W; Jeske D; Hofman P; Homann D; Beaudoin L; Schrike C; Von Herrath M; Lehuen A; Glaichenhaus N. 2002. Tolerance to islet antigens and prevention from diabetes induced by limited apoptosis of pancreatic beta cells.. In: . . MGI: J:132052
Hull ML; Johan MZ; Hodge WL; Robertson SA; Ingman WV. 2012. Host-derived TGFB1 deficiency suppresses lesion development in a mouse model of endometriosis.. In: . . MGI: J:181959
Hunter CA; Ellis-Neyes LA; Slifer T; Kanaly S; Grunig G; Fort M; Rennick D; Araujo FG. 1997. IL-10 is required to prevent immune hyperactivity during infection with Trypanosoma cruzi.. In: . . MGI: J:110835
Ichimura Y; Waguri S; Sou YS; Kageyama S; Hasegawa J; Ishimura R; Saito T; Yang Y; Kouno T; Fukutomi T; Hoshii T; Hirao A; Takagi K; Mizushima T; Motohashi H; Lee MS; Yoshimori T; Tanaka K; Yamamoto M; Komatsu M. 2013. Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy.. In: . . MGI: J:203811
Ingman WV; Robertson SA. 2008. Mammary gland development in transforming growth factor beta1 null mutant mice: systemic and epithelial effects.. In: . . MGI: J:140882
Ingman WV; Robertson SA. 2007. Transforming growth factor-beta1 null mutation causes infertility in male mice associated with testosterone deficiency and sexual dysfunction.. In: . . MGI: J:129629
Ingman WV; Robker RL; Woittiez K; Robertson SA. 2006. Null mutation in transforming growth factor beta1 disrupts ovarian function and causes oocyte incompetence and early embryo arrest.. In: . . MGI: J:129446
Ippolito GC; Hoi KH; Reddy ST; Carroll SM; Ge X; Rogosch T; Zemlin M; Shultz LD; Ellington AD; Vandenberg CL; Georgiou G. 2012. Antibody repertoires in humanized NOD-scid-IL2Rgamma(null) mice and human B cells reveals human-like diversification and tolerance checkpoints in the mouse.. In: . . MGI: J:187283
Ishii T; Zhao Y; Sozer S; Shi J; Zhang W; Hoffman R; Xu M. 2007. Behavior of CD34+ cells isolated from patients with polycythemia vera in NOD/SCID mice.. In: . . MGI: J:132540
Ishii-Ohba H; Kobayashi S; Nishimura M; Shimada Y; Tsuji H; Sado T; Ogiu T. 2007. Existence of a threshold-like dose for gamma-ray induction of thymic lymphomas and no susceptibility to radiation-induced solid tumors in SCID mice.. In: . . MGI: J:120953
Ishikawa F; Yasukawa M; Lyons B; Yoshida S; Miyamoto T; Yoshimoto G; Watanabe T; Akashi K; Shultz LD; Harada M. 2005. Development of functional human blood and immune systems in NOD/SCID/IL2 receptor {gamma} chain(null) mice.. In: . . MGI: J:142411
Ito M; Hiramatsu H; Kobayashi K; Suzue K; Kawahata M; Hioki K; Ueyama Y; Koyanagi Y; Sugamura K; Tsuji K; Heike T; Nakahata T. 2002. NOD/SCID/gamma(c)(null) mouse: an excellent recipient mouse model for engraftment of human cells.. In: . . MGI: J:163373
Ito R; Katano I; Ida-Tanaka M; Kamisako T; Kawai K; Suemizu H; Aiso S; Ito M. 2012. Efficient xenoengraftment in severe immunodeficient NOD/Shi-scid IL2rgammanull mice is attributed to a lack of CD11c+B220+CD122+ cells.. In: . . MGI: J:190612
Ito R; Negishi N; Irie N; Matsuo K; Suzuki D; Katano I; Hayakawa E; Kawai K; Kamisako T; Eto T; Ogura T; Hozumi K; Ando K; Aiso S; Tamaoki N; Habu S; Ito M. 2012. Osteosclerosis and inhibition of human hematopoiesis in NOG mice expressing human Delta-like 1 in osteoblasts.. In: . . MGI: J:203591
Ito R; Takahashi T; Katano I; Kawai K; Kamisako T; Ogura T; Ida-Tanaka M; Suemizu H; Nunomura S; Ra C; Mori A; Aiso S; Ito M. 2013. Establishment of a human allergy model using human IL-3/GM-CSF-transgenic NOG mice.. In: . . MGI: J:205873
Ito T; Seyama T; Kyoizumi S; Teraoka S; Iwamoto KS; Mizuno T; Tsuyama N; Asahara T; Dohi K; Akiyama M. 1995. The usefulness of severe combined immunodeficiency (SCID) mice to study human carcinogenesis.. In: . . MGI: J:23712
Iwai H; Abe M; Hirose S; Tsushima F; Tezuka K; Akiba H; Yagita H; Okumura K; Kohsaka H; Miyasaka N; Azuma M. 2003. Involvement of inducible costimulator-B7 homologous protein costimulatory pathway in murine lupus nephritis.. In: . . MGI: J:120381
Jaakkola I; Jalkanen S; Hanninen A. 2003. Diabetogenic T cells are primed both in pancreatic and gut-associated lymph nodes in NOD mice.. In: . . MGI: J:87142
Jaeschke A; Rincon M; Doran B; Reilly J; Neuberg D; Greiner DL; Shultz LD; Rossini AA; Flavell RA; Davis RJ. 2005. Disruption of the Jnk2 (Mapk9) gene reduces destructive insulitis and diabetes in a mouse model of type I diabetes.. In: . . MGI: J:99056
Jahchan NS; Lim JS; Bola B; Morris K; Seitz G; Tran KQ; Xu L; Trapani F; Morrow CJ; Cristea S; Coles GL; Yang D; Vaka D; Kareta MS; George J; Mazur PK; Nguyen T; Anderson WC; Dylla SJ; Blackhall F; Peifer M; Dive C; Sage J. 2016. Identification and Targeting of Long-Term Tumor-Propagating Cells in Small Cell Lung Cancer.. In: . . MGI: J:238584
Jaiswal S; Pearson T; Friberg H; Shultz LD; Greiner DL; Rothman AL; Mathew A. 2009. Dengue virus infection and virus-specific HLA-A2 restricted immune responses in humanized NOD-scid IL2rgammanull mice.. In: . . MGI: J:154110
Janes MR; Limon JJ; So L; Chen J; Lim RJ; Chavez MA; Vu C; Lilly MB; Mallya S; Ong ST; Konopleva M; Martin MB; Ren P; Liu Y; Rommel C; Fruman DA. 2010. Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor.. In: . . MGI: J:162611
Jimenez de Bagues MP; de Martino A; Quintana JF; Alcaraz A; Pardo J. 2011. Course of Infection with the Emergent Pathogen Brucella microti in Immunocompromised Mice.. In: . . MGI: J:175995
Johnson RM; Papp E; Grandal I; Kowalski PE; Nutter L; Wong RC; Joseph-George AM; Danska JS; Guidos CJ. 2014. MuLV-related endogenous retroviral elements and Flt3 participate in aberrant end-joining events that promote B-cell leukemogenesis.. In: . . MGI: J:211638
Jones-Carson J; Vazquez-Torres A; Balish E. 1995. Defective killing of Candida albicans hyphae by neutrophils from beige mice.. In: . . MGI: J:25930
Juelke K; Killig M; Luetke-Eversloh M; Parente E; Gruen J; Morandi B; Ferlazzo G; Thiel A; Schmitt-Knosalla I; Romagnani C. 2010. CD62L expression identifies a unique subset of polyfunctional CD56dim NK cells.. In: . . MGI: J:163485
Jun HS; Santamaria P; Lim HW; Zhang ML; Yoon JW. 1999. Absolute requirement of macrophages for the development and activation of beta-cell cytotoxic CD8+ T-cells in T-cell receptor transgenic NOD mice.. In: . . MGI: J:108751
Kagari T; Doi H; Shimozato T. 2002. The importance of IL-1 beta and TNF-alpha, and the noninvolvement of IL-6, in the development of monoclonal antibody-induced arthritis.. In: . . MGI: J:120707
Kahiri CN; Khalil MW; Tekpetey F; Kidder GM. 2006. Leydig cell function in mice lacking connexin43.. In: . . MGI: J:112888
Kalaany NY; Sabatini DM. 2009. Tumours with PI3K activation are resistant to dietary restriction.. In: . . MGI: J:147281
Kalscheuer H; Onoe T; Dahmani A; Li HW; Holzl M; Yamada K; Sykes M. 2014. Xenograft tolerance and immune function of human T cells developing in pig thymus xenografts.. In: . . MGI: J:209878
Kariya R; Taura M; Suzu S; Kai H; Katano H; Okada S. 2014. HIV protease inhibitor Lopinavir induces apoptosis of primary effusion lymphoma cells via suppression of NF-kappaB pathway.. In: . . MGI: J:204517
Katakura K; Lee J; Rachmilewitz D; Li G; Eckmann L; Raz E. 2005. Toll-like receptor 9-induced type I IFN protects mice from experimental colitis.. In: . . MGI: J:110027
Katakura T; Yoshida T; Kobayashi M; Herndon DN; Suzuki F. 2005. Immunological control of methicillin-resistant Staphylococcus aureus (MRSA) infection in an immunodeficient murine model of thermal injuries.. In: . . MGI: J:107603
Kawaguchi-Miyashita M; Shimada S; Kurosu H; Kato-Nagaoka N; Matsuoka Y; Ohwaki M; Ishikawa H; Nanno M. 2001. An accessory role of TCRgammadelta (+) cells in the exacerbation of inflammatory bowel disease in TCRalpha mutant mice.. In: . . MGI: J:68810
Kawahara M; Pandolfi A; Bartholdy B; Barreyro L; Will B; Roth M; Okoye-Okafor UC; Todorova TI; Figueroa ME; Melnick A; Mitsiades CS; Steidl U. 2012. H2.0-like homeobox regulates early hematopoiesis and promotes acute myeloid leukemia.. In: . . MGI: J:191823
Kayama H; Ueda Y; Sawa Y; Jeon SG; Ma JS; Okumura R; Kubo A; Ishii M; Okazaki T; Murakami M; Yamamoto M; Yagita H; Takeda K. 2012. Intestinal CX3C chemokine receptor 1high (CX3CR1high) myeloid cells prevent T-cell-dependent colitis.. In: . . MGI: J:182225
Kazerounian S; Gerald D; Huang M; Chin YR; Udayakumar D; Zheng N; O'Donnell RK; Perruzzi C; Mangiante L; Pourat J; Phung TL; Bravo-Nuevo A; Shechter S; McNamara S; Duhadaway JB; Kocher ON; Brown LF; Toker A; Prendergast GC; Benjamin LE. 2013. RhoB differentially controls Akt function in tumor cells and stromal endothelial cells during breast tumorigenesis.. In: . . MGI: J:194113
Kelly MN; Zheng M; Ruan S; Kolls J; D'Souza A; Shellito JE. 2013. Memory CD4+ T Cells Are Required for Optimal NK Cell Effector Functions against the Opportunistic Fungal Pathogen Pneumocystis murina.. In: . . MGI: J:190830
Kemp CJ; Vo K; Gurley KE. 1999. Resistance to skin tumorigenesis in DNAPK-deficient SCID mice is not due to immunodeficiency but results from hypersensitivity to TPA-induced apoptosis.. In: . . MGI: J:58425
Khaled AR; Li WQ; Huang J; Fry TJ; Khaled AS; Mackall CL; Muegge K; Young HA; Durum SK. 2002. Bax deficiency partially corrects interleukin-7 receptor alpha deficiency.. In: . . MGI: J:93139
Kharbanda S; Pandey P; Jin S; Inoue S; Bharti A; Yuan ZM; Weichselbaum R; Weaver D; Kufe D. 1997. Functional interaction between DNA-PK and c-Abl in response to DNA damage.. In: . . MGI: J:116399
Kiaris H; Chatzistamou I; Trimis G; Frangou-Plemmenou M; Pafiti-Kondi A; Kalofoutis A. 2005. Evidence for nonautonomous effect of p53 tumor suppressor in carcinogenesis.. In: . . MGI: J:97031
Kiefer K; Nakajima PB; Oshinsky J; Seeholzer SH; Radic M; Bosma GC; Bosma MJ. 2008. Antigen receptor editing in anti-DNA transitional B cells deficient for surface IgM.. In: . . MGI: J:160356
Kiefer K; Oshinsky J; Kim J; Nakajima PB; Bosma GC; Bosma MJ. 2007. The catalytic subunit of DNA-protein kinase (DNA-PKcs) is not required for Ig class-switch recombination.. In: . . MGI: J:125895
Kim KD; Srikanth S; Yee MK; Mock DC; Lawson GW; Gwack Y. 2011. ORAI1 deficiency impairs activated T cell death and enhances T cell survival.. In: . . MGI: J:179333
Kim S; Dubrovska A; Salamone RJ; Walker JR; Grandinetti KB; Bonamy GM; Orth AP; Elliott J; Porta DG; Garcia-Echeverria C; Reddy VA. 2013. FGFR2 promotes breast tumorigenicity through maintenance of breast tumor-initiating cells.. In: . . MGI: J:195822
King MA; Covassin L; Brehm MA; Racki W; Pearson T; Leif J; Laning J; Fodor W; Foreman O; Burzenski L; Chase TH; Gott B; Rossini AA; Bortell R; Shultz LD; Greiner DL. 2009. Human peripheral blood leucocyte non-obese diabetic-severe combined immunodeficiency interleukin-2 receptor gamma chain gene mouse model of xenogeneic graft-versus-host-like disease and the role of host major histocompatibility complex.. In: . . MGI: J:151390
Kinkel SA; Galeev R; Flensburg C; Keniry A; Breslin K; Gilan O; Lee S; Liu J; Chen K; Gearing LJ; Moore DL; Alexander WS; Dawson M; Majewski IJ; Oshlack A; Larsson J; Blewitt ME. 2015. Jarid2 regulates hematopoietic stem cell function by acting with polycomb repressive complex 2.. In: . . MGI: J:222052
Kitamura K; Nakamoto Y; Kaneko S; Mukaida N. 2004. Pivotal roles of interleukin-6 in transmural inflammation in murine T cell transfer colitis.. In: . . MGI: J:94173
Kitaura H; Zhou P; Kim HJ; Novack DV; Ross FP; Teitelbaum SL. 2005. M-CSF mediates TNF-induced inflammatory osteolysis.. In: . . MGI: J:104533
Klein MA; Frigg R; Flechsig E; Raeber AJ; Kalinke U; Bluethmann H; Bootz F; Suter M; Zinkernagel RM; Aguzzi A. 1997. A crucial role for B cells in neuroinvasive scrapie [see comments]. In: . . MGI: J:44933
Klug F; Prakash H; Huber PE; Seibel T; Bender N; Halama N; Pfirschke C; Voss RH; Timke C; Umansky L; Klapproth K; Schakel K; Garbi N; Jager D; Weitz J; Schmitz-Winnenthal H; Hammerling GJ; Beckhove P. 2013. Low-dose irradiation programs macrophage differentiation to an iNOS(+)/M1 phenotype that orchestrates effective T cell immunotherapy.. In: . . MGI: J:206743
Kobayashi M; Nakamura K; Cornforth M; Suzuki F. 2012. Role of M2b macrophages in the acceleration of bacterial translocation and subsequent sepsis in mice exposed to whole body [137Cs] gamma-irradiation.. In: . . MGI: J:188934
Kodama T; Hikita H; Kawaguchi T; Saito Y; Tanaka S; Shigekawa M; Shimizu S; Li W; Miyagi T; Kanto T; Hiramatsu N; Tatsumi T; Takehara T. 2013. The Bcl-2 homology domain 3 (BH3)-only proteins Bim and bid are functionally active and restrained by anti-apoptotic Bcl-2 family proteins in healthy liver.. In: . . MGI: J:203931
Kometani K; Aoki M; Kawamata S; Shinozuka Y; Era T; Taniwaki M; Hattori M; Minato N. 2006. Role of SPA-1 in phenotypes of chronic myelogenous leukemia induced by BCR-ABL-expressing hematopoietic progenitors in a mouse model.. In: . . MGI: J:114993
Kong L; Robinson CP; Peck AB; Vela-Roch N; Sakata KM; Dang H; Talal N; Humphreys-Beher MG. 1998. Inappropriate apoptosis of salivary and lacrimal gland epithelium of immunodeficient NOD-scid mice.. In: . . MGI: J:53650
Kota DJ; Wiggins LL; Yoon N; Lee RH. 2013. TSG-6 produced by hMSCs delays the onset of autoimmune diabetes by suppressing Th1 development and enhancing tolerogenicity.. In: . . MGI: J:208563
Krishnamurthy S; Warner KA; Dong Z; Imai A; Nor C; Ward BB; Helman JI; Taichman RS; Bellile EL; McCauley LK; Polverini PJ; Prince ME; Wicha MS; Nor JE. 2014. Endothelial interleukin-6 defines the tumorigenic potential of primary human cancer stem cells.. In: . . MGI: J:218558
Ksander BR; Kolovou PE; Wilson BJ; Saab KR; Guo Q; Ma J; McGuire SP; Gregory MS; Vincent WJ; Perez VL; Cruz-Guilloty F; Kao WW; Call MK; Tucker BA; Zhan Q; Murphy GF; Lathrop KL; Alt C; Mortensen LJ; Lin CP; Zieske JD; Frank MH; Frank NY. 2014. ABCB5 is a limbal stem cell gene required for corneal development and repair.. In: . . MGI: J:213708
Kumar P; Ban HS; Kim SS; Wu H; Pearson T; Greiner DL; Laouar A; Yao J; Haridas V; Habiro K; Yang YG; Jeong JH; Lee KY; Kim YH; Kim SW; Peipp M; Fey GH; Manjunath N; Shultz LD; Lee SK; Shankar P. 2008. T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice.. In: . . MGI: J:142409
Kunisawa J; Gohda M; Kurashima Y; Ishikawa I; Higuchi M; Kiyono H. 2008. Sphingosine 1-phosphate-dependent trafficking of peritoneal B cells requires functional NF{kappa}B-inducing kinase in stromal cells.. In: . . MGI: J:134340
Kupfer TM; Crawford ML; Pham K; Gill RG. 2005. MHC-mismatched islet allografts are vulnerable to autoimmune recognition in vivo.. In: . . MGI: J:107508
Kurkjian C; Hollifield M; Lines JL; Rogosky A; Empey KM; Qureshi M; Brown SA; Garvy BA. 2012. Alveolar Macrophages in Neonatal Mice Are Inherently Unresponsive to Pneumocystis murina Infection.. In: . . MGI: J:186637
Kwun J; Hu H; Schadde E; Roenneburg D; Sullivan KA; DeMartino J; Burlingham WJ; Knechtle SJ. 2007. Altered distribution of H60 minor H antigen-specific CD8 T cells and attenuated chronic vasculopathy in minor histocompatibility antigen mismatched heart transplantation in Cxcr3-/- mouse recipients.. In: . . MGI: J:155042
Larcher F; Del Rio M; Serrano F; Segovia JC; Ramirez A; Meana A; Page A; Abad JL; Gonzalez MA; Bueren J; Bernad A; Jorcano JL. 2001. A cutaneous gene therapy approach to human leptin deficiencies: correction of the murine ob/ob phenotype using leptin-targeted keratinocyte grafts.. In: . . MGI: J:115148
Law KM; Komarova NL; Yewdall AW; Lee RK; Herrera OL; Wodarz D; Chen BK. 2016. In Vivo HIV-1 Cell-to-Cell Transmission Promotes Multicopy Micro-compartmentalized Infection.. In: . . MGI: J:238305
Lawres LA; Garg A; Kumar V; Bruzual I; Forquer IP; Renard I; Virji AZ; Boulard P; Rodriguez EX; Allen AJ; Pou S; Wegmann KW; Winter RW; Nilsen A; Mao J; Preston DA; Belperron AA; Bockenstedt LK; Hinrichs DJ; Riscoe MK; Doggett JS; Ben Mamoun C. 2016. Radical cure of experimental babesiosis in immunodeficient mice using a combination of an endochin-like quinolone and atovaquone.. In: . . MGI: J:236267
Lazarus JJ; Meadows MJ; Lintner RE; Wooten RM. 2006. IL-10 deficiency promotes increased Borrelia burgdorferi clearance predominantly through enhanced innate immune responses.. In: . . MGI: J:140484
Lee HM; Wysoczynski M; Liu R; Shin DM; Kucia M; Botto M; Ratajczak J; Ratajczak MZ. 2010. Mobilization studies in complement-deficient mice reveal that optimal AMD3100 mobilization of hematopoietic stem cells depends on complement cascade activation by AMD3100-stimulated granulocytes.. In: . . MGI: J:158026
Lee SM; Yang H; Tartar DM; Gao B; Luo X; Ye SQ; Zaghouani H; Fang D. 2011. Prevention and treatment of diabetes with resveratrol in a non-obese mouse model of type 1 diabetes.. In: . . MGI: J:169586
Lefevre S; Knedla A; Tennie C; Kampmann A; Wunrau C; Dinser R; Korb A; Schnaker EM; Tarner IH; Robbins PD; Evans CH; Sturz H; Steinmeyer J; Gay S; Scholmerich J; Pap T; Muller-Ladner U; Neumann E. 2009. Synovial fibroblasts spread rheumatoid arthritis to unaffected joints.. In: . . MGI: J:155763
Leiter EH; Prochazka M; Shultz LD. 1987. Effect of immunodeficiency on diabetogenesis in genetically diabetic (db/db) mice.. In: . . MGI: J:32752
Leung J; Suh WK. 2013. Host B7-H4 regulates antitumor T cell responses through inhibition of myeloid-derived suppressor cells in a 4T1 tumor transplantation model.. In: . . MGI: J:204842
Li B; Sharpe EE; Maupin AB; Teleron AA; Pyle AL; Carmeliet P; Young PP. 2006. VEGF and PlGF promote adult vasculogenesis by enhancing EPC recruitment and vessel formation at the site of tumor neovascularization.. In: . . MGI: J:111344
Li CR; Mueller EE; Bradley LM. 2014. Islet antigen-specific Th17 cells can induce TNF-alpha-dependent autoimmune diabetes.. In: . . MGI: J:209355
Li E; Zhou P; Singer SM. 2006. Neuronal nitric oxide synthase is necessary for elimination of Giardia lamblia infections in mice.. In: . . MGI: J:126256
Li G; Zhang L; Chen E; Wang J; Jiang X; Chen JH; Wickman G; Amundson K; Bergqvist S; Zobel J; Buckman D; Baxi SM; Bender SL; Casperson GF; Hu-Lowe DD. 2010. Dual functional monoclonal antibody PF-04605412 targets integrin alpha5beta1 and elicits potent antibody-dependent cellular cytotoxicity.. In: . . MGI: J:167600
Li S; Ling C; Zhong L; Li M; Su Q; He R; Tang Q; Greiner DL; Shultz LD; Brehm MA; Flotte TR; Mueller C; Srivastava A; Gao G. 2015. Efficient and Targeted Transduction of Nonhuman Primate Liver With Systemically Delivered Optimized AAV3B Vectors.. In: . . MGI: J:230567
Li SW; Koya V; Li Y; Donelan W; Lin P; Reeves WH; Yang LJ. 2010. Pancreatic duodenal homeobox 1 protein is a novel beta-cell-specific autoantigen for type I diabetes.. In: . . MGI: J:156607
Li T; Ramirez K; Palacios R. 1996. Distinct patterns of Fas cell surface expression during development of T- or B-lymphocyte lineages in normal, scid, and mutant mice lacking or overexpressing p53, bcl-2, or rag-2 genes.. In: . . MGI: J:31364
Li X; Sterling JA; Fan KH; Vessella RL; Shyr Y; Hayward SW; Matrisian LM; Bhowmick NA. 2012. Loss of TGF-beta responsiveness in prostate stromal cells alters chemokine levels and facilitates the development of mixed osteoblastic/osteolytic bone lesions.. In: . . MGI: J:205394
Li Y; Su J; Dingzhang X; Zhang J; Yoshimoto M; Liu S; Bijian K; Gupta A; Squire JA; Alaoui Jamali MA; Bismar TA. 2011. PTEN deletion and heme oxygenase-1 overexpression cooperate in prostate cancer progression and are associated with adverse clinical outcome.. In: . . MGI: J:171247
Liao MJ; Zhang XX; Hill R; Gao J; Qumsiyeh MB; Nichols W; Van Dyke T. 1998. No requirement for V(D)J recombination in p53-deficient thymic lymphoma.. In: . . MGI: J:47667
Liao YJ; Fang CC; Yen CH; Hsu SM; Wang CK; Huang SF; Liang YC; Lin YY; Chu YT; Arthur Chen YM. 2015. Niemann-Pick type C2 protein regulates liver cancer progression via modulating ERK1/2 pathway: Clinicopathological correlations and therapeutical implications.. In: . . MGI: J:222874
Libby SJ; Brehm MA; Greiner DL; Shultz LD; McClelland M; Smith KD; Cookson BT; Karlinsey JE; Kinkel TL; Porwollik S; Canals R; Cummings LA; Fang FC. 2010. Humanized nonobese diabetic-scid IL2rgammanull mice are susceptible to lethal Salmonella Typhi infection.. In: . . MGI: J:163745
Liebe B; Petukhova G; Barchi M; Bellani M; Braselmann H; Nakano T; Pandita TK; Jasin M; Fornace A; Meistrich ML; Baarends WM; Schimenti J; de Lange T; Keeney S; Camerini-Otero RD; Scherthan H. 2006. Mutations that affect meiosis in male mice influence the dynamics of the mid-preleptotene and bouquet stages.. In: . . MGI: J:147391
Liebler JM; Lutzko C; Banfalvi A; Senadheera D; Aghamohammadi N; Crandall ED; Borok Z. 2008. Retention of human bone marrow-derived cells in murine lungs following bleomycin-induced lung injury.. In: . . MGI: J:138638
Lieke T; Steeg C; Graefe SE; Fleischer B; Jacobs T. 2006. Interaction of natural killer cells with Trypanosoma cruzi-infected fibroblasts.. In: . . MGI: J:112856
Lin P; Li W; Yao Z; Sun Y; Wang L; Li S; Chen L. 2015. Oral administration of PDX1 confers protection against insulitis in the non-obese diabetic (NOD) mice.. In: . . MGI: J:232937
Liu D; Zhang T; Marshall AJ; Okkenhaug K; Vanhaesebroeck B; Uzonna JE. 2009. The p110delta isoform of phosphatidylinositol 3-kinase controls susceptibility to Leishmania major by regulating expansion and tissue homing of regulatory T cells.. In: . . MGI: J:151583
Liu R; Liu C; Chen D; Yang WH; Liu X; Liu CG; Dugas CM; Tang F; Zheng P; Liu Y; Wang L. 2015. FOXP3 Controls an miR-146/NF-kappaB Negative Feedback Loop That Inhibits Apoptosis in Breast Cancer Cells.. In: . . MGI: J:220159
Liu Y; Carlsson R; Comabella M; Wang J; Kosicki M; Carrion B; Hasan M; Wu X; Montalban X; Dziegiel MH; Sellebjerg F; Sorensen PS; Helin K; Issazadeh-Navikas S. 2014. FoxA1 directs the lineage and immunosuppressive properties of a novel regulatory T cell population in EAE and MS.. In: . . MGI: J:208760
Llamas B; Belanger S; Picard S; Deschepper CF. 2007. Cardiac mass and cardiomyocyte size are governed by different genetic loci on either autosomes or chromosome Y in recombinant inbred mice.. In: . . MGI: J:127219
Lode HN; Xiang R; Pertl U; Forster E; Schoenberger SP; Gillies SD; Reisfeld RA. 2000. Melanoma immunotherapy by targeted IL-2 depends on CD4(+) T-cell help mediated by CD40/CD40L interaction.. In: . . MGI: J:62762
Londono D; Bai Y; Zuckert WR; Gelderblom H; Cadavid D. 2005. Cardiac apoptosis in severe relapsing fever borreliosis.. In: . . MGI: J:104291
Long AH; Haso WM; Shern JF; Wanhainen KM; Murgai M; Ingaramo M; Smith JP; Walker AJ; Kohler ME; Venkateshwara VR; Kaplan RN; Patterson GH; Fry TJ; Orentas RJ; Mackall CL. 2015. 4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors.. In: . . MGI: J:228468
Lou YR; Peng QY; Li T; Medvecky CM; Lin Y; Shih WJ; Conney AH; Shapses S; Wagner GC; Lu YP. 2011. Effects of high-fat diets rich in either omega-3 or omega-6 fatty acids on UVB-induced skin carcinogenesis in SKH-1 mice.. In: . . MGI: J:173643
Lu L; Ghose AK; Quail MR; Albom MS; Durkin JT; Holskin BP; Angeles TS; Meyer SL; Ruggeri BA; Cheng M. 2009. ALK mutants in the kinase domain exhibit altered kinase activity and differential sensitivity to small molecule ALK inhibitors.. In: . . MGI: J:149248
Lu M; Kardel MD; O'Connor MD; Eaves CJ. 2009. Enhanced generation of hematopoietic cells from human hepatocarcinoma cell-stimulated human embryonic and induced pluripotent stem cells.. In: . . MGI: J:151435
Lucas S; Taront S; Magnan C; Fauconnier L; Delacre M; Macia L; Delanoye A; Verwaerde C; Spriet C; Saule P; Goormachtigh G; Heliot L; Ktorza A; Movassat J; Polakowska R; Auriault C; Poulain-Godefroy O; Di Santo J; Froguel P; Wolowczuk I. 2012. Interleukin-7 regulates adipose tissue mass and insulin sensitivity in high-fat diet-fed mice through lymphocyte-dependent and independent mechanisms.. In: . . MGI: J:187900
Lukacs RU; Memarzadeh S; Wu H; Witte ON. 2010. Bmi-1 is a crucial regulator of prostate stem cell self-renewal and malignant transformation.. In: . . MGI: J:168487
Luo X; Tarbell KV; Yang H; Pothoven K; Bailey SL; Ding R; Steinman RM; Suthanthiran M. 2007. Dendritic cells with TGF-beta1 differentiate naive CD4+CD25- T cells into islet-protective Foxp3+ regulatory T cells.. In: . . MGI: J:125908
MacKenzie DA; Sollinger HW; Hullett DA. 1996. Acute graft rejection of human fetal pancreas allografts using donor-specific human peripheral blood lymphocytes in the SCID mouse.. In: . . MGI: J:33268
Madlambayan GJ; Meacham AM; Hosaka K; Mir S; Jorgensen M; Scott EW; Siemann DW; Cogle CR. 2010. Leukemia regression by vascular disruption and antiangiogenic therapy.. In: . . MGI: J:164541
Maeda K; Nagasawa H; Furukawa A; Hisaeda H; Himeno K. 1994. Split tolerance between spleen and lymph node cells in severe combined immunodeficiency mice grafted with AKR fetal liver cells.. In: . . MGI: J:22574
Mahler M; Bristol IJ; Leiter EH; Workman AE; Birkenmeier EH; Elson CO; Sundberg JP. 1998. Differential susceptibility of inbred mouse strains to dextran sulfate sodium-induced colitis.. In: . . MGI: J:46553
Majeti R; Park CY; Weissman IL. 2007. Identification of a hierarchy of multipotent hematopoietic progenitors in human cord blood.. In: . . MGI: J:142413
Majumder M; Xin X; Liu L; Tutunea-Fatan E; Rodriguez-Torres M; Vincent K; Postovit LM; Hess D; Lala PK. 2016. COX-2 Induces Breast Cancer Stem Cells via EP4/PI3K/AKT/NOTCH/WNT Axis.. In: . . MGI: J:238376
Mamalaki C; Elliott J; Norton T; Yannoutsos N; Townsend AR; Chandler P; Simpson E; Kioussis D. 1993. Positive and negative selection in transgenic mice expressing a T-cell receptor specific for influenza nucleoprotein and endogenous superantigen.. In: . . MGI: J:113713
Mangada J; Pearson T; Brehm MA; Wicker LS; Peterson LB; Shultz LD; Serreze DV; Rossini AA; Greiner DL. 2009. Idd loci synergize to prolong islet allograft survival induced by costimulation blockade in NOD mice.. In: . . MGI: J:146982
Manis JP; Dudley D; Kaylor L; Alt FW. 2002. IgH class switch recombination to IgG1 in DNA-PKcs-deficient B cells.. In: . . MGI: J:113521
Manuel JA; Gawronska-Kozak B. 2006. Matrix metalloproteinase 9 (MMP-9) is upregulated during scarless wound healing in athymic nude mice.. In: . . MGI: J:116052
Marigo I; Zilio S; Desantis G; Mlecnik B; Agnellini AH; Ugel S; Sasso MS; Qualls JE; Kratochvill F; Zanovello P; Molon B; Ries CH; Runza V; Hoves S; Bilocq AM; Bindea G; Mazza EM; Bicciato S; Galon J; Murray PJ; Bronte V. 2016. T Cell Cancer Therapy Requires CD40-CD40L Activation of Tumor Necrosis Factor and Inducible Nitric-Oxide-Synthase-Producing Dendritic Cells.. In: . . MGI: J:234978
Marino E; Walters SN; Villanueva JE; Richards JL; Mackay CR; Grey ST. 2014. BAFF regulates activation of self-reactive T cells through B-cell dependent mechanisms and mediates protection in NOD mice.. In: . . MGI: J:209374
Marron MP; Graser RT; Chapman HD; Serreze DV. 2002. Functional evidence for the mediation of diabetogenic T cell responses by HLA-A2.1 MHC class I molecules through transgenic expression in NOD mice.. In: . . MGI: J:109851
Marsden MD; Kovochich M; Suree N; Shimizu S; Mehta R; Cortado R; Bristol G; An DS; Zack JA. 2012. HIV Latency in the Humanized BLT Mouse.. In: . . MGI: J:179389
Masaki T; Qu J; Cholewa-Waclaw J; Burr K; Raaum R; Rambukkana A. 2013. Reprogramming adult Schwann cells to stem cell-like cells by leprosy bacilli promotes dissemination of infection.. In: . . MGI: J:214507
Matsuoka K; Saito M; Shibata K; Sekine M; Shitara H; Taya C; Zhang X; Takahashi TA; Kohno K; Kikkawa Y; Yonekawa H. 2013. Generation of mouse models for type 1 diabetes by selective depletion of pancreatic beta cells using toxin receptor-mediated cell knockout.. In: . . MGI: J:204420
Maykel J; Liu JH; Li H; Shultz LD; Greiner DL; Houghton J. 2014. NOD-scidIl2rg (tm1Wjl) and NOD-Rag1 (null) Il2rg (tm1Wjl) : a model for stromal cell-tumor cell interaction for human colon cancer.. In: . . MGI: J:227975
McCool TL; Weiser JN. 2004. Limited role of antibody in clearance of Streptococcus pneumoniae in a murine model of colonization.. In: . . MGI: J:93131
McDermott SP; Eppert K; Lechman ER; Doedens M; Dick JE. 2010. Comparison of human cord blood engraftment between immunocompromised mouse strains.. In: . . MGI: J:162809
McIntosh BE; Brown ME; Duffin BM; Maufort JP; Vereide DT; Slukvin II; Thomson JA. 2015. Nonirradiated NOD,B6.SCID Il2rgamma(-/-)Kit(W41/W41) (NBSGW) Mice Support Multilineage Engraftment of Human Hematopoietic Cells.. In: . . MGI: J:218738
Mehta S; Huillard E; Kesari S; Maire CL; Golebiowski D; Harrington EP; Alberta JA; Kane MF; Theisen M; Ligon KL; Rowitch DH; Stiles CD. 2011. The Central Nervous System-Restricted Transcription Factor Olig2 Opposes p53 Responses to Genotoxic Damage in Neural Progenitors and Malignant Glioma.. In: . . MGI: J:169930
Meissner N; Swain S; McInnerney K; Han S; Harmsen AG. 2010. Type-I IFN signaling suppresses an excessive IFN-gamma response and thus prevents lung damage and chronic inflammation during pneumocystis (PC) clearance in CD4 T cell-competent mice.. In: . . MGI: J:161163
Meissner NN; Swain S; Tighe M; Harmsen A; Harmsen A. 2005. Role of type I IFNs in pulmonary complications of Pneumocystis murina infection.. In: . . MGI: J:98407
Miller RD; Hogg J; Ozaki JH; Gell D; Jackson SP; Riblet R. 1995. Gene for the catalytic subunit of mouse DNA-dependent protein kinase maps to the scid locus.. In: . . MGI: J:29679
Mishra A; Brown AL; Yao X; Yang S; Park SJ; Liu C; Dagur PK; McCoy JP; Keeran KJ; Nugent GZ; Jeffries KR; Qu X; Yu ZX; Levine SJ; Chung JH. 2015. Dendritic cells induce Th2-mediated airway inflammatory responses to house dust mite via DNA-dependent protein kinase.. In: . . MGI: J:221358
Mishra A; Das B; Nath M; Iyer S; Kesarwani A; Bhattacharjee J; Arindkar S; Sahay P; Jain K; Sahu P; Sinha P; Velpandian T; Nagarajan P; Upadhyay P. 2017. A novel immunodeficient NOD.SCID-rd1 mouse model of retinitis pigmentosa to investigate potential therapeutics and pathogenesis of retinal degeneration.. In: . . MGI: J:242067
Mishra R; Chen AT; Welsh RM; Szomolanyi-Tsuda E. 2010. NK cells and gammadelta T cells mediate resistance to polyomavirus-induced tumors.. In: . . MGI: J:162921
Mizrahi K; Stein J; Pearl-Yafe M; Kaplan O; Yaniv I; Askenasy N. 2010. Regulatory functions of TRAIL in hematopoietic progenitors: human umbilical cord blood and murine bone marrow transplantation.. In: . . MGI: J:162490
Montecino-Rodriguez E; Leathers H; Dorshkind K. 2006. Identification of a B-1 B cell-specified progenitor.. In: . . MGI: J:112481
Monteiro JP; Benjamin A; Costa ES; Barcinski MA; Bonomo A. 2005. Normal hematopoiesis is maintained by activated bone marrow CD4+ T cells.. In: . . MGI: J:96600
Morris SC; Heidorn SM; Herbert DR; Perkins C; Hildeman DA; Khodoun MV; Finkelman FD. 2009. Endogenously produced IL-4 nonredundantly stimulates CD8+ T cell proliferation.. In: . . MGI: J:144327
Morrison C; Smith GC; Stingl L; Jackson SP; Wagner EF; Wang ZQ. 1997. Genetic interaction between PARP and DNA-PK in V(D)J recombination and tumorigenesis.. In: . . MGI: J:75374
Mosier DE; Stell KL; Gulizia RJ; Torbett BE; Gilmore GL. 1993. Homozygous scid/scid;beige/beige mice have low levels of spontaneous or neonatal T cell-induced B cell generation.. In: . . MGI: J:3479
Mota J; Rico-Hesse R. 2009. Humanized mice show clinical signs of dengue fever according to infecting virus genotype.. In: . . MGI: J:153922
Mustafi R; Dougherty U; Shah H; Dehghan H; Gliksberg A; Wu J; Zhu H; Joseph L; Hart J; Dive C; Fichera A; Threadgill D; Bissonnette M. 2012. Both stromal cell and colonocyte epidermal growth factor receptors control HCT116 colon cancer cell growth in tumor xenografts.. In: . . MGI: J:192954
Mutwiri G K; Kosecka U; Benjamin M; Rosendal S; Perdue M; Butler D G. 2001. Mycobacterium avium subspecies paratuberculosis triggers intestinal pathophysiologic changes in beige/scid mice.. In: . . MGI: J:73720
Nacht M; Strasser A; Chan YR; Harris AW; Schlissel M; Bronson RT; Jacks T. 1996. Mutations in the p53 and SCID genes cooperate in tumorigenesis.. In: . . MGI: J:35055
Nakayama M; Beilke JN; Jasinski JM; Kobayashi M; Miao D; Li M; Coulombe MG; Liu E; Elliott JF; Gill RG; Eisenbarth GS. 2007. Priming and effector dependence on insulin B:9-23 peptide in NOD islet autoimmunity.. In: . . MGI: J:124210
Naramura M; Nandwani N; Gu H; Band V; Band H. 2010. Rapidly fatal myeloproliferative disorders in mice with deletion of Casitas B-cell lymphoma (Cbl) and Cbl-b in hematopoietic stem cells.. In: . . MGI: J:164365
Nemoto Y; Kanai T; Takahara M; Oshima S; Okamoto R; Tsuchiya K; Matsumoto S; Watanabe M. 2013. Th1/Th17-mediated interstitial pneumonia in chronic colitis mice independent of intestinal microbiota.. In: . . MGI: J:204854
Niimi N; Sugo N; Aratani Y; Koyama H. 2005. Genetic interaction between DNA polymerase beta and DNA-PKcs in embryogenesis and neurogenesis.. In: . . MGI: J:106364
Nishiyama Y; Hamada H; Nonaka S; Yamamoto H; Nanno M; Katayama Y; Takahashi H; Ishikawa H. 2002. Homeostatic regulation of intestinal villous epithelia by B lymphocytes.. In: . . MGI: J:126867
Nonaka S; Naito T; Chen H; Yamamoto M; Moro K; Kiyono H; Hamada H; Ishikawa H. 2005. Intestinal gammadelta T cells develop in mice lacking thymus, all lymph nodes, Peyer's patches, and isolated lymphoid follicles.. In: . . MGI: J:96579
Nonoyama S; Smith FO; Bernstein ID; Ochs HD. 1993. Strain-dependent leakiness of mice with severe combined immune deficiency.. In: . . MGI: J:4610
Noorchashm H; Reed AJ; Rostami SY; Mozaffari R; Zekavat G; Koeberlein B; Caton AJ; Naji A. 2006. B cell-mediated antigen presentation is required for the pathogenesis of acute cardiac allograft rejection.. In: . . MGI: J:140848
Notley CA; Inglis JJ; Alzabin S; McCann FE; McNamee KE; Williams RO. 2008. Blockade of tumor necrosis factor in collagen-induced arthritis reveals a novel immunoregulatory pathway for Th1 and Th17 cells.. In: . . MGI: J:140651
Nucera S; Giustacchini A; Boccalatte F; Calabria A; Fanciullo C; Plati T; Ranghetti A; Garcia-Manteiga J; Cittaro D; Benedicenti F; Lechman ER; Dick JE; Ponzoni M; Ciceri F; Montini E; Gentner B; Naldini L. 2016. miRNA-126 Orchestrates an Oncogenic Program in B Cell Precursor Acute Lymphoblastic Leukemia.. In: . . MGI: J:232327
O'Boyle G; Fox CR; Walden HR; Willet JD; Mavin ER; Hine DW; Palmer JM; Barker CE; Lamb CA; Ali S; Kirby JA. 2012. Chemokine receptor CXCR3 agonist prevents human T-cell migration in a humanized model of arthritic inflammation.. In: . . MGI: J:182231
O'Hara JR; Skinn AC; MacNaughton WK; Sherman PM; Sharkey KA. 2006. Consequences of Citrobacter rodentium infection on enteroendocrine cells and the enteric nervous system in the mouse colon.. In: . . MGI: J:135756
O'Malley JT; Eri RD; Stritesky GL; Mathur AN; Chang HC; Hogenesch H; Srinivasan M; Kaplan MH. 2008. STAT4 isoforms differentially regulate Th1 cytokine production and the severity of inflammatory bowel disease.. In: . . MGI: J:142733
O'Reilly LA; Harris AW; Strasser A. 1997. bcl-2 transgene expression promotes survival and reduces proliferation of CD3-CD4-CD8- T cell progenitors.. In: . . MGI: J:93122
O'Reilly LA; Harris AW; Tarlinton DM; Corcoran LM; Strasser A. 1997. Expression of a bcl-2 transgene reduces proliferation and slows turnover of developing B lymphocytes in vivo.. In: . . MGI: J:93123
Ochiai M; Ubagai T; Kawamori T; Imai H; Sugimura T; Nakagama H. 2001. High susceptibility of Scid mice to colon carcinogenesis induced by azoxymethane indicates a possible caretaker role for DNA-dependent protein kinase.. In: . . MGI: J:84343
Ohsugi T; Kiuchi Y; Shimoda K; Oguri S; Maejima K. 1996. Translocation of bacteria from the gastrointestinal tract in immunodeficient mice.. In: . . MGI: J:31261
Oida T; Suzuki K; Nanno M; Kanamori Y; Saito H; Kubota E; Kato S; Itoh M; Kaminogawa S; Ishikawa H. 2000. Role of gut cryptopatches in early extrathymic maturation of intestinal intraepithelial T cells.. In: . . MGI: J:112139
Okada K; Shoda J; Taguchi K; Maher JM; Ishizaki K; Inoue Y; Ohtsuki M; Goto N; Takeda K; Utsunomiya H; Oda K; Warabi E; Ishii T; Osaka K; Hyodo I; Yamamoto M. 2008. Ursodeoxycholic acid stimulates Nrf2-mediated hepatocellular transport, detoxification, and antioxidative stress systems in mice.. In: . . MGI: J:142149
Okazaki T; Okazaki IM; Wang J; Sugiura D; Nakaki F; Yoshida T; Kato Y; Fagarasan S; Muramatsu M; Eto T; Hioki K; Honjo T. 2011. PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice.. In: . . MGI: J:176845
Okazuka K; Wakabayashi Y; Kashihara M; Inoue J; Sato T; Yokoyama M; Aizawa S; Aizawa Y; Mishima Y; Kominami R. 2005. p53 prevents maturation of T cell development to the immature CD4(-)CD8(+) stage in Bcl11b(-/-) mice.. In: . . MGI: J:96179
Omori K; Mitsuhashi M; Ishiyama K; Nair I; Rawson J; Todorov I; Kandeel F; Mullen Y. 2011. mRNA of the pro-apoptotic gene BBC3 serves as a molecular marker for TNF-alpha-induced islet damage in humans.. In: . . MGI: J:175299
Opata MM; Ye Z; Hollifield M; Garvy BA. 2013. B Cell Production of Tumor Necrosis Factor in Response to Pneumocystis murina Infection in Mice.. In: . . MGI: J:201876
Origanti S; Cai SR; Munir AZ; White LS; Piwnica-Worms H. 2013. Synthetic lethality of Chk1 inhibition combined with p53 and/or p21 loss during a DNA damage response in normal and tumor cells.. In: . . MGI: J:193369
Oruganti SR; Torres DJ; Krebsbach S; Asperti-Boursin F; Winters J; Matlawska-Wasowska K; Winter SS; Halsey C; Cannon JL. 2017. CARMA1 is a novel regulator of T-ALL disease and leukemic cell migration to the CNS.. In: . . MGI: J:237842
Osmond DG; Kim N; Manoukian R; Phillips RA; Rico-Vargas SA; Jacobsen K. 1992. Dynamics and localization of early B-lymphocyte precursor cells (pro-B cells) in the bone marrow of scid mice.. In: . . MGI: J:737
Owyang AM; Zaph C; Wilson EH; Guild KJ; McClanahan T; Miller HR; Cua DJ; Goldschmidt M; Hunter CA; Kastelein RA; Artis D. 2006. Interleukin 25 regulates type 2 cytokine-dependent immunity and limits chronic inflammation in the gastrointestinal tract.. In: . . MGI: J:123808
Ozaki H; Mori K; Nakagawa Y; Hoshikawa S; Ito S; Inoue Y; Takai T; Yoshida K. 2009. Autoimmune thyroiditis in Fcgamma receptor-deficient nonobese diabetic mice.. In: . . MGI: J:151452
Paciorkowski N; Porte P; Shultz LD; Rajan TV. 2000. B1 B lymphocytes play a critical role in host protection against lymphatic filarial parasites.. In: . . MGI: J:112016
Paliwal P; Conboy IM. 2011. Inhibitors of tyrosine phosphatases and apoptosis reprogram lineage-marked differentiated muscle to myogenic progenitor cells.. In: . . MGI: J:190199
Pancewicz J; Taylor JM; Datta A; Baydoun HH; Waldmann TA; Hermine O; Nicot C. 2010. Notch signaling contributes to proliferation and tumor formation of human T-cell leukemia virus type 1-associated adult T-cell leukemia.. In: . . MGI: J:164350
Papagiannakopoulos T; Friedmann-Morvinski D; Neveu P; Dugas JC; Gill RM; Huillard E; Liu C; Zong H; Rowitch DH; Barres BA; Verma IM; Kosik KS. 2012. Pro-neural miR-128 is a glioma tumor suppressor that targets mitogenic kinases.. In: . . MGI: J:186143
Papeta N; Zheng Z; Schon EA; Brosel S; Altintas MM; Nasr SH; Reiser J; D'Agati VD; Gharavi AG. 2010. Prkdc participates in mitochondrial genome maintenance and prevents Adriamycin-induced nephropathy in mice.. In: . . MGI: J:166909
Park CW; Ryu HW; Ryu KY. 2012. Locus coeruleus neurons are resistant to dysfunction and degeneration by maintaining free ubiquitin levels although total ubiquitin levels decrease upon disruption of polyubiquitin gene Ubb.. In: . . MGI: J:181255
Park JS; Kim IK; Han S; Park I; Kim C; Bae J; Oh SJ; Lee S; Kim JH; Woo DC; He Y; Augustin HG; Kim I; Lee D; Koh GY. 2016. Normalization of Tumor Vessels by Tie2 Activation and Ang2 Inhibition Enhances Drug Delivery and Produces a Favorable Tumor Microenvironment.. In: . . MGI: J:238058
Pathania R; Ramachandran S; Elangovan S; Padia R; Yang P; Cinghu S; Veeranan-Karmegam R; Arjunan P; Gnana-Prakasam JP; Sadanand F; Pei L; Chang CS; Choi JH; Shi H; Manicassamy S; Prasad PD; Sharma S; Ganapathy V; Jothi R; Thangaraju M. 2015. DNMT1 is essential for mammary and cancer stem cell maintenance and tumorigenesis.. In: . . MGI: J:222799
Pathania R; Ramachandran S; Mariappan G; Thakur P; Shi H; Choi JH; Manicassamy S; Kolhe R; Prasad PD; Sharma S; Lokeshwar BL; Ganapathy V; Thangaraju M. 2016. Combined Inhibition of DNMT and HDAC Blocks the Tumorigenicity of Cancer Stem-like Cells and Attenuates Mammary Tumor Growth.. In: . . MGI: J:232034
Pauza ME; Dobbs CM; He J; Patterson T; Wagner S; Anobile BS; Bradley BJ; Lo D; Haskins K. 2004. T-cell receptor transgenic response to an endogenous polymorphic autoantigen determines susceptibility to diabetes.. In: . . MGI: J:89082
Pearson T; Greiner DL; Shultz LD. 2008. Creation of 'humanized' mice to study human immunity.. In: . . MGI: J:151386
Pearson T; Shultz LD; Lief J; Burzenski L; Gott B; Chase T; Foreman O; Rossini AA; Bottino R; Trucco M; Greiner DL. 2008. A new immunodeficient hyperglycaemic mouse model based on the Ins2 ( Akita ) mutation for analyses of human islet and beta stem and progenitor cell function.. In: . . MGI: J:138005
Pearson T; Shultz LD; Miller D; King M; Laning J; Fodor W; Cuthbert A; Burzenski L; Gott B; Lyons B; Foreman O; Rossini AA; Greiner DL. 2008. Non-obese diabetic-recombination activating gene-1 (NOD-Rag1 null) interleukin (IL)-2 receptor common gamma chain (IL2r gamma null) null mice: a radioresistant model for human lymphohaematopoietic engraftment.. In: . . MGI: J:140388
Pedraza-Alva G; Koulnis M; Charland C; Thornton T; Clements JL; Schlissel MS; Rincon M. 2006. Activation of p38 MAP kinase by DNA double-strand breaks in V(D)J recombination induces a G2/M cell cycle checkpoint.. In: . . MGI: J:105987
Pei Y; Moore CE; Wang J; Tewari AK; Eroshkin A; Cho YJ; Witt H; Korshunov A; Read TA; Sun JL; Schmitt EM; Miller CR; Buckley AF; McLendon RE; Westbrook TF; Northcott PA; Taylor MD; Pfister SM; Febbo PG; Wechsler-Reya RJ. 2012. An Animal Model of MYC-Driven Medulloblastoma.. In: . . MGI: J:181463
Percy DH; Auger DC; Croy BA. 1994. Signs and lesions of experimental Sendai virus infection in two genetically distinct strains of SCID/beige mice.. In: . . MGI: J:17913
Percy DH; Barta JR. 1993. Spontaneous and experimental infections in scid and scid/beige mice.. In: . . MGI: J:4752
Perone MJ; Bertera S; Tawadrous ZS; Shufesky WJ; Piganelli JD; Baum LG; Trucco M; Morelli AE. 2006. Dendritic cells expressing transgenic galectin-1 delay onset of autoimmune diabetes in mice.. In: . . MGI: J:139444
Petitto JM; Huang Z; Lo J; Streit WJ. 2003. IL-2 gene knockout affects T lymphocyte trafficking and the microglial response to regenerating facial motor neurons.. In: . . MGI: J:105891
Phillips JM; Parish NM; Drage M; Cooke A. 2001. Cutting edge: interactions through the IL-10 receptor regulate autoimmune diabetes.. In: . . MGI: J:119045
Pierce EM; Carpenter K; Jakubzick C; Kunkel SL; Flaherty KR; Martinez FJ; Hogaboam CM. 2007. Therapeutic targeting of CC ligand 21 or CC chemokine receptor 7 abrogates pulmonary fibrosis induced by the adoptive transfer of human pulmonary fibroblasts to immunodeficient mice.. In: . . MGI: J:120124
Pierce MA; Chapman HD; Post CM; Svetlanov A; Efrat S; Horwitz M; Serreze DV. 2003. Adenovirus early region 3 antiapoptotic 10.4K, 14.5K, and 14.7K genes decrease the incidence of autoimmune diabetes in NOD mice.. In: . . MGI: J:83195
Plenter RJ; Grazia TJ; Nelson DP; Zamora MR; Gill RG; Pietra BA. 2015. Ectopic expression of Fas Ligand on cardiomyocytes renders cardiac allografts resistant to CD4(+) T-cell mediated rejection.. In: . . MGI: J:223254
Porubsky S; Wang S; Kiss E; Dehmel S; Bonrouhi M; Dorn T; Luckow B; Brakebusch C; Grone HJ. 2011. Rhoh deficiency reduces peripheral T-cell function and attenuates allogenic transplant rejection.. In: . . MGI: J:174659
Powrie F; Leach MW; Mauze S; Menon S; Caddle LB; Coffman RL. 1994. Inhibition of Th1 responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells.. In: . . MGI: J:133778
Prochazka M; Gaskins HR; Shultz LD; Leiter EH. 1992. The nonobese diabetic scid mouse: model for spontaneous thymomagenesis associated with immunodeficiency.. In: . . MGI: J:513
Purwana I; Zheng J; Li X; Deurloo M; Son DO; Zhang Z; Liang C; Shen E; Tadkase A; Feng ZP; Li Y; Hasilo C; Paraskevas S; Bortell R; Greiner DL; Atkinson M; Prud'homme GJ; Wang Q. 2014. GABA promotes human beta-cell proliferation and modulates glucose homeostasis.. In: . . MGI: J:230144
Qing Y; Lin Y; Gerson SL. 2012. An intrinsic BM hematopoietic niche occupancy defect of HSC in scid mice facilitates exogenous HSC engraftment.. In: . . MGI: J:181738
Qualls JE; Kaplan AM; van Rooijen N; Cohen DA. 2006. Suppression of experimental colitis by intestinal mononuclear phagocytes.. In: . . MGI: J:113033
Quintana E; Shackleton M; Sabel MS; Fullen DR; Johnson TM; Morrison SJ. 2008. Efficient tumour formation by single human melanoma cells.. In: . . MGI: J:142408
Rappa G; Mercapide J; Lorico A. 2012. Spontaneous Formation of Tumorigenic Hybrids between Breast Cancer and Multipotent Stromal Cells Is a Source of Tumor Heterogeneity.. In: . . MGI: J:184798
Rauch DA; Hurchla MA; Harding JC; Deng H; Shea LK; Eagleton MC; Niewiesk S; Lairmore MD; Piwnica-Worms D; Rosol TJ; Weber JD; Ratner L; Weilbaecher KN. 2010. The ARF tumor suppressor regulates bone remodeling and osteosarcoma development in mice.. In: . . MGI: J:168312
Rauner G; Leviav A; Mavor E; Barash I. 2013. Development of Foreign Mammary Epithelial Morphology in the Stroma of Immunodeficient Mice.. In: . . MGI: J:204342
Read TA; Fogarty MP; Markant SL; McLendon RE; Wei Z; Ellison DW; Febbo PG; Wechsler-Reya RJ. 2009. Identification of CD15 as a marker for tumor-propagating cells in a mouse model of medulloblastoma.. In: . . MGI: J:144811
Riggs J; Stowers R. 1996. Ability of spleen, peritoneal cavity, and lymph node B cells to reconstitute serum immunoglobulin in SCID mice.. In: . . MGI: J:32916
Riggs JE; Feeney AJ; Kirven M; Mosier DE. 1994. VH11 bias and normal V-D-J junctions in SCID B lymphocytes rescued by neonatal T cell transfer.. In: . . MGI: J:19789
Rival C; Samy E; Setiady Y; Tung K. 2013. Cutting edge: Ly49C/I(-) neonatal NK cells predispose newborns to autoimmune ovarian disease induced by maternal autoantibody.. In: . . MGI: J:205867
Rivera J; Zaragoza O; Casadevall A. 2005. Antibody-mediated protection against Cryptococcus neoformans pulmonary infection is dependent on B cells.. In: . . MGI: J:95620
Roberts JL; Abe R; Shores EW; Singer A. 1992. Expression of Mls determinants in mice exhibiting the severe combined immunodeficiency (scid) mutation or X-linked immunodeficiency (xid) defect.. In: . . MGI: J:2072
Rochford R; Ohrt C; Baresel PC; Campo B; Sampath A; Magill AJ; Tekwani BL; Walker LA. 2013. Humanized mouse model of glucose 6-phosphate dehydrogenase deficiency for in vivo assessment of hemolytic toxicity.. In: . . MGI: J:201977
Rodgers JT; King KY; Brett JO; Cromie MJ; Charville GW; Maguire KK; Brunson C; Mastey N; Liu L; Tsai CR; Goodell MA; Rando TA. 2014. mTORC1 controls the adaptive transition of quiescent stem cells from G0 to G(Alert).. In: . . MGI: J:213273
Rolink A; Melchers F; Andersson J. 1996. The SCID but not the RAG-2 gene product is required for S mu-S epsilon heavy chain class switching.. In: . . MGI: J:36026
Rosario CO; Ko MA; Haffani YZ; Gladdy RA; Paderova J; Pollett A; Squire JA; Dennis JW; Swallow CJ. 2010. Plk4 is required for cytokinesis and maintenance of chromosomal stability.. In: . . MGI: J:159310
Rosen C; Shezen E; Aronovich A; Klionsky YZ; Yaakov Y; Assayag M; Biton IE; Tal O; Shakhar G; Ben-Hur H; Shneider D; Vaknin Z; Sadan O; Evron S; Freud E; Shoseyov D; Wilschanski M; Berkman N; Fibbe WE; Hagin D; Hillel-Karniel C; Krentsis IM; Bachar-Lustig E; Reisner Y. 2015. Preconditioning allows engraftment of mouse and human embryonic lung cells, enabling lung repair in mice.. In: . . MGI: J:228759
Roths JB; Smith AL; Sidman CL. 1993. Lethal exacerbation of Pneumocystis carinii pneumonia in severe combined immunodeficiency mice after infection by pneumonia virus of mice.. In: . . MGI: J:109921
Rotolo JA; Mesicek J; Maj J; Truman JP; Haimovitz-Friedman A; Kolesnick R; Fuks Z. 2010. Regulation of ceramide synthase-mediated crypt epithelium apoptosis by DNA damage repair enzymes.. In: . . MGI: J:156862
Roy N; Takeuchi KK; Ruggeri JM; Bailey P; Chang D; Li J; Leonhardt L; Puri S; Hoffman MT; Gao S; Halbrook CJ; Song Y; Ljungman M; Malik S; Wright CV; Dawson DW; Biankin AV; Hebrok M; Crawford HC. 2016. PDX1 dynamically regulates pancreatic ductal adenocarcinoma initiation and maintenance.. In: . . MGI: J:238701
Ruan S; McKinley L; Zheng M; Rudner X; D'Souza A; Kolls JK; Shellito JE. 2008. Interleukin-12 and host defense against murine Pneumocystis pneumonia.. In: . . MGI: J:134470
Ruetsch NR; Bosma GC; Bosma MJ. 2000. Unexpected rearrangement and expression of the immunoglobulin lambda1 locus in scid mice.. In: . . MGI: J:62701
Rui J; Deng S; Lebastchi J; Clark PL; Usmani-Brown S; Herold KC. 2016. Methylation of insulin DNA in response to proinflammatory cytokines during the progression of autoimmune diabetes in NOD mice.. In: . . MGI: J:232925
Rynda-Apple A; Dobrinen E; McAlpine M; Read A; Harmsen A; Richert LE; Calverley M; Pallister K; Voyich J; Wiley JA; Johnson B; Young M; Douglas T; Harmsen AG. 2012. Virus-Like Particle-Induced Protection Against MRSA Pneumonia Is Dependent on IL-13 and Enhancement of Phagocyte Function.. In: . . MGI: J:185523
Saeed H; Abdallah BM; Ditzel N; Catala-Lehnen P; Qiu W; Amling M; Kassem M. 2011. Telomerase-deficient mice exhibit bone loss owing to defects in osteoblasts and increased osteoclastogenesis by inflammatory microenvironment.. In: . . MGI: J:233117
Sakai D; Nakamura Y; Nakai T; Mishima T; Kato S; Grad S; Alini M; Risbud MV; Chan D; Cheah KS; Yamamura K; Masuda K; Okano H; Ando K; Mochida J. 2012. Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc.. In: . . MGI: J:225067
Salem ML; Al-Khami AA; El-Naggar SA; Diaz-Montero CM; Chen Y; Cole DJ. 2010. Cyclophosphamide induces dynamic alterations in the host microenvironments resulting in a Flt3 ligand-dependent expansion of dendritic cells.. In: . . MGI: J:159482
Samy ET; Meyer CA; Caplazi P; Langrish CL; Lora JM; Bluethmann H; Peng SL. 2007. Cutting edge: Modulation of intestinal autoimmunity and IL-2 signaling by sphingosine kinase 2 independent of sphingosine 1-phosphate.. In: . . MGI: J:153014
Sandri S; Bobisse S; Moxley K; Lamolinara A; De Sanctis F; Boschi F; Sbarbati A; Fracasso G; Ferrarini G; Hendriks RW; Cavallini C; Scupoli MT; Sartoris S; Iezzi M; Nishimura MI; Bronte V; Ugel S. 2016. Feasibility of Telomerase-Specific Adoptive T-cell Therapy for B-cell Chronic Lymphocytic Leukemia and Solid Malignancies.. In: . . MGI: J:232028
Santidrian AF; Matsuno-Yagi A; Ritland M; Seo BB; LeBoeuf SE; Gay LJ; Yagi T; Felding-Habermann B. 2013. Mitochondrial complex I activity and NAD+/NADH balance regulate breast cancer progression.. In: . . MGI: J:196392
Saville SP; Lazzell AL; Chaturvedi AK; Monteagudo C; Lopez-Ribot JL. 2008. Use of a genetically engineered strain to evaluate the pathogenic potential of yeast cell and filamentous forms during Candida albicans systemic infection in immunodeficient mice.. In: . . MGI: J:130296
Savinov AY; Rozanov DV; Strongin AY. 2007. Specific inhibition of autoimmune T cell transmigration contributes to beta cell functionality and insulin synthesis in non-obese diabetic (NOD) mice.. In: . . MGI: J:126809
Savinov AY; Tcherepanov A; Green EA; Flavell RA; Chervonsky AV. 2003. Contribution of Fas to diabetes development.. In: . . MGI: J:81416
Savouret C; Brisson E; Essers J; Kanaar R; Pastink A; te Riele H; Junien C; Gourdon G. 2003. CTG repeat instability and size variation timing in DNA repair-deficient mice.. In: . . MGI: J:83373
Scheeren FA; Kuo AH; van Weele LJ; Cai S; Glykofridis I; Sikandar SS; Zabala M; Qian D; Lam JS; Johnston D; Volkmer JP; Sahoo D; van de Rijn M; Dirbas FM; Somlo G; Kalisky T; Rothenberg ME; Quake SR; Clarke MF. 2014. A cell-intrinsic role for TLR2-MYD88 in intestinal and breast epithelia and oncogenesis.. In: . . MGI: J:217693
Schito ML; Barta JR. 1997. Nonspecific immune responses and mechanisms of resistance to Eimeria papillata infections in mice.. In: . . MGI: J:41839
Schmidt RE; Dorsey DA; Beaudet LN; Frederick KE; Parvin CA; Plurad SB; Levisetti MG. 2003. Non-obese diabetic mice rapidly develop dramatic sympathetic neuritic dystrophy: a new experimental model of diabetic autonomic neuropathy.. In: . . MGI: J:86318
Schon MP; Schon M; Warren HB; Donohue JP; Parker CM. 2000. Cutaneous inflammatory disorder in integrin alphaE (CD103)-deficient mice.. In: . . MGI: J:110810
Schroder PM; Khattar M; Baum CE; Miyahara Y; Chen W; Vyas R; Muralidharan S; Mierzejewska B; Stepkowski SM. 2015. PD-1-dependent restoration of self-tolerance in the NOD mouse model of diabetes after transient anti-TCRbeta mAb therapy.. In: . . MGI: J:220839
Schuler W; Weiler IJ; Schuler A; Phillips RA; Rosenberg N; Mak TW; Kearney JF; Perry RP; Bosma MJ. 1986. Rearrangement of antigen receptor genes is defective in mice with severe combined immune deficiency.. In: . . MGI: J:8420
Searles S; Gauss K; Wilkison M; Hoyt TR; Dobrinen E; Meissner N. 2013. Modulation of inflammasome-mediated pulmonary immune activation by type I IFNs protects bone marrow homeostasis during systemic responses to Pneumocystis lung infection.. In: . . MGI: J:205844
Seehus CR; Aliahmad P; de la Torre B; Iliev ID; Spurka L; Funari VA; Kaye J. 2015. The development of innate lymphoid cells requires TOX-dependent generation of a common innate lymphoid cell progenitor.. In: . . MGI: J:232838
Seif AE; Barrett DM; Milone M; Brown VI; Grupp SA; Reid GS. 2009. Long-term protection from syngeneic acute lymphoblastic leukemia by CpG ODN-mediated stimulation of innate and adaptive immune responses.. In: . . MGI: J:152910
Sekiguchi J; Ferguson DO; Chen HT; Yang EM; Earle J; Frank K; Whitlow S; Gu Y; Xu Y; Nussenzweig A; Alt FW. 2001. Genetic interactions between ATM and the nonhomologous end-joining factors in genomic stability and development.. In: . . MGI: J:68074
Sela U; Olds P; Park A; Schlesinger SJ; Steinman RM. 2011. Dendritic cells induce antigen-specific regulatory T cells that prevent graft versus host disease and persist in mice.. In: . . MGI: J:178615
Serpe CJ; Kohm AP; Huppenbauer CB; Sanders VM; Jones KJ. 1999. Exacerbation of facial motoneuron loss after facial nerve transection in severe combined immunodeficient (scid) mice.. In: . . MGI: J:120563
Serre L; Fazilleau N; Guerder S. 2015. Central tolerance spares the private high-avidity CD4(+) T-cell repertoire specific for an islet antigen in NOD mice.. In: . . MGI: J:229782
Serreze DV; Chapman HD; Varnum DS; Gerling I; Leiter EH; Shultz LD. 1997. Initiation of autoimmune diabetes in NOD/Lt mice is MHC class I-dependent.. In: . . MGI: J:39473
Serreze DV; Johnson EA; Chapman HD; Graser RT; Marron MP; DiLorenzo TP; Silveira P; Yoshimura Y; Nathenson SG; Joyce S. 2001. Autoreactive diabetogenic T-cells in NOD mice can efficiently expand from a greatly reduced precursor pool.. In: . . MGI: J:71050
Serreze DV; Leiter EH; Hanson MS; Christianson SW; Shultz LD; Hesselton RM; Greiner DL. 1995. Emv30null NOD-scid mice. An improved host for adoptive transfer of autoimmune diabetes and growth of human lymphohematopoietic cells.. In: . . MGI: J:29951
Severe S; Gauvrit A; Vu AT; Bach JM. 2007. CD8(+) T lymphocytes specific for glutamic acid decarboxylase 90-98 epitope mediate diabetes in NOD(SCID) mouse.. In: . . MGI: J:119811
Sewald X; Ladinsky MS; Uchil PD; Beloor J; Pi R; Herrmann C; Motamedi N; Murooka TT; Brehm MA; Greiner DL; Shultz LD; Mempel TR; Bjorkman PJ; Kumar P; Mothes W. 2015. Retroviruses use CD169-mediated trans-infection of permissive lymphocytes to establish infection.. In: . . MGI: J:226540
Shang L; Hua H; Foo K; Martinez H; Watanabe K; Zimmer M; Kahler DJ; Freeby M; Chung W; LeDuc C; Goland R; Leibel RL; Egli D. 2014. beta-cell dysfunction due to increased ER stress in a stem cell model of Wolfram syndrome.. In: . . MGI: J:208989
Shellito JE; Kolls JK; Olariu R; Beck JM. 1996. Nitric oxide and host defense against Pneumocystis carinii infection in a mouse model.. In: . . MGI: J:31163
Shen Y; Park CS; Suppipat K; Mistretta TA; Puppi M; Horton TM; Rabin K; Gray NS; Meijerink JPP; Lacorazza HD. 2017. Inactivation of KLF4 promotes T-cell acute lymphoblastic leukemia and activates the MAP2K7 pathway.. In: . . MGI: J:241802
Shibata S; Asano T; Ogura A; Hashimoto N; Hayakawa J; Uetsuka K ; Nakayama H ; Doi K. 1997. SCID-bg mice as xenograft recipients.. In: . . MGI: J:40569
Shoji S; Watanabe H; Katoh O; Masaoka Y; Matsuura S; Tauchi H; Endo S; Komatsu K. 1998. Developmental malformations and intrauterine deaths in gamma-ray-irradiated scid mouse embryos.. In: . . MGI: J:51083
Shores EW; Nakayama T; Wiest DL; Takahama Y; Sharrow S; Singer A. 1993. Structurally distinct T cell receptor complexes on developmentally distinct T cell populations in severe combined immunodeficiency mice expressing a TCR beta transgene.. In: . . MGI: J:111476
Shukla A; Rai K; Shukla V; Chaturvedi NK; Bociek RG; Pirruccello SJ; Band H; Lu R; Joshi SS. 2016. Sprouty 2: a novel attenuator of B-cell receptor and MAPK-Erk signaling in CLL.. In: . . MGI: J:232635
Shultz LD; Banuelos S; Lyons B; Samuels R; Burzenski L; Gott B; Lang P; Leif J; Appel M; Rossini A; Greiner DL. 2003. NOD/LtSz-Rag1nullPfpnull mice: a new model system with increased levels of human peripheral leukocyte and hematopoietic stem-cell engraftment.. In: . . MGI: J:109843
Shultz LD; Ishikawa F; Greiner DL. 2007. Humanized mice in translational biomedical research.. In: . . MGI: J:142414
Shultz LD; Saito Y; Najima Y; Tanaka S; Ochi T; Tomizawa M; Doi T; Sone A; Suzuki N; Fujiwara H; Yasukawa M; Ishikawa F. 2010. Generation of functional human T-cell subsets with HLA-restricted immune responses in HLA class I expressing NOD/SCID/IL2r gamma(null) humanized mice.. In: . . MGI: J:162315
Shultz LD; Schweitzer PA; Christianson SW; Gott B; Schweitzer IB; Tennent B; McKenna S; Mobraaten L; Rajan TV; Greiner DL; Leiter EH. 1995. Multiple defects in innate and adaptive immunologic function in NOD/LtSz-scid mice.. In: . . MGI: J:22026
Shurin MR; Potapovich AI; Tyurina YY; Tourkova IL; Shurin GV; Kagan VE. 2009. Recognition of live phosphatidylserine-labeled tumor cells by dendritic cells: a novel approach to immunotherapy of skin cancer.. In: . . MGI: J:147072
Simard C; Klein SJ; Mak T; Jolicoeur P. 1997. Studies of the susceptibility of nude, CD4 knockout, and SCID mutant mice to the disease induced by the murine AIDS defective virus.. In: . . MGI: J:38897
Simons BW; Hurley PJ; Huang Z; Ross AE; Miller R; Marchionni L; Berman DM; Schaeffer EM. 2012. Wnt signaling though beta-catenin is required for prostate lineage specification.. In: . . MGI: J:190538
Simpson-Abelson MR; Sonnenberg GF; Takita H; Yokota SJ; Conway TF Jr; Kelleher RJ Jr; Shultz LD; Barcos M; Bankert RB. 2008. Long-term engraftment and expansion of tumor-derived memory T cells following the implantation of non-disrupted pieces of human lung tumor into NOD-scid IL2Rgamma(null) mice.. In: . . MGI: J:142412
Smith AA; Li J; Liu B; Hunter D; Pyles M; Gillette M; Dhamdhere GR; Abo A; Oro A; Helms JA. 2016. Activating Hair Follicle Stem Cells via R-spondin2 to Stimulate Hair Growth.. In: . . MGI: J:235025
Smythies LE; Waites KB; Lindsey JR; Harris PR; Ghiara P; Smith PD. 2000. Helicobacter pylori-induced mucosal inflammation is Th1 mediated and exacerbated in IL-4, but not IFN-gamma, gene-deficient mice.. In: . . MGI: J:120556
Song X; Guo Y; Duo S; Che J; Wu C; Ochiya T; Ding M; Deng H. 2009. A mouse model of inducible liver injury caused by tet-on regulated urokinase for studies of hepatocyte transplantation.. In: . . MGI: J:154703
Spranger S; Jeremias I; Wilde S; Leisegang M; Starck L; Mosetter B; Uckert W; Heemskerk MH; Schendel DJ; Frankenberger B. 2012. TCR-transgenic lymphocytes specific for HMMR/Rhamm limit tumor outgrowth in vivo.. In: . . MGI: J:183769
Stalder AK; Carson MJ; Pagenstecher A; Asensio VC; Kincaid C; Benedict M; Powell HC; Masliah E; Campbell IL. 1998. Late-onset chronic inflammatory encephalopathy in immune-competent and severe combined immune-deficient (SCID) mice with astrocyte-targeted expression of tumor necrosis factor.. In: . . MGI: J:106595
Stokes KY; Calahan L; Hamric CM; Russell JM; Granger DN. 2009. CD40/CD40L contributes to hypercholesterolemia-induced microvascular inflammation.. In: . . MGI: J:146361
Stone JL; McMillan RE; Skaar DA; Bradshaw JM; Jirtle RL; Sikes ML. 2012. DNA Double-Strand Breaks Relieve USF-Mediated Repression of Dbeta2 Germline Transcription in Developing Thymocytes.. In: . . MGI: J:181246
Stracker TH; Couto SS; Cordon-Cardo C; Matos T; Petrini JH. 2008. Chk2 suppresses the oncogenic potential of DNA replication-associated DNA damage.. In: . . MGI: J:138550
Stracker TH; Williams BR; Deriano L; Theunissen JW; Adelman CA; Roth DB; Petrini JH. 2009. Artemis and nonhomologous end joining-independent influence of DNA-dependent protein kinase catalytic subunit on chromosome stability.. In: . . MGI: J:144749
Strasser A; Harris AW; Corcoran LM; Cory S. 1994. Bcl-2 expression promotes B- but not T-lymphoid development in scid mice.. In: . . MGI: J:17426
Stratford EW; Bostad M; Castro R; Skarpen E; Berg K; Hogset A; Myklebost O; Selbo PK. 2013. Photochemical internalization of CD133-targeting immunotoxins efficiently depletes sarcoma cells with stem-like properties and reduces tumorigenicity.. In: . . MGI: J:202381
Strowig T; Chijioke O; Carrega P; Arrey F; Meixlsperger S; Ramer PC; Ferlazzo G; Munz C. 2010. Human NK cells of mice with reconstituted human immune system components require preactivation to acquire functional competence.. In: . . MGI: J:167434
Su MA; Davini D; Cheng P; Giang K; Fan U; DeVoss JJ; Johannes KP; Taylor L; Shum AK; Valenzise M; Meloni A; Bour-Jordan H; Anderson MS. 2012. Defective autoimmune regulator-dependent central tolerance to myelin protein zero is linked to autoimmune peripheral neuropathy.. In: . . MGI: J:188686
Su X; Hu Q; Kristan JM; Costa C; Shen Y; Gero D; Matis LA; Wang Y. 2000. Significant role for Fas in the pathogenesis of autoimmune diabetes.. In: . . MGI: J:127009
Suffia I; Reckling SK; Salay G; Belkaid Y. 2005. A role for CD103 in the retention of CD4+CD25+ Treg and control of Leishmania major infection.. In: . . MGI: J:98414
Sugiarto S; Persson AI; Munoz EG; Waldhuber M; Lamagna C; Andor N; Hanecker P; Ayers-Ringler J; Phillips J; Siu J; Lim DA; Vandenberg S; Stallcup W; Berger MS; Bergers G; Weiss WA; Petritsch C. 2011. Asymmetry-defective oligodendrocyte progenitors are glioma precursors.. In: . . MGI: J:175969
Sugiura K; Taketani S; Yoshimura T; Nishino T; Nishino N; Fujisawa J; Hisha H; Inaba T; Ikehara S. 2007. Effect of hepatocyte growth factor on long term hematopoiesis of human progenitor cells in transgenic-severe combined immunodeficiency mice.. In: . . MGI: J:126823
Sun X; Robertson SA; Ingman WV. 2013. Regulation of epithelial cell turnover and macrophage phenotype by epithelial cell-derived transforming growth factor beta1 in the mammary gland.. In: . . MGI: J:197873
Sundberg JP (ed.). 1994. Handbook of Mouse Mutations with Skin and Hair Abnormalities: Animal Models and Biomedical Tools. In: Handbook of Mouse Mutations with Skin and Hair Abnormalities: Animal Models and Biomedical Tools. CRC Press, Boca Raton. MGI: J:30359
Sundberg JP; Adkison DL; Bedigian HG. 1991. Skeletal muscle rhabdomyosarcomas in inbred laboratory mice.. In: . . MGI: J:24311
Sundberg JP; Boggess D; Sundberg BA; Beamer WG; Shultz LD. 1993. Epidermal dendritic cell populations in the flaky skin mutant mouse.. In: . . MGI: J:14506
Swaims AY; Khani F; Zhang Y; Roberts AI; Devadas S; Shi Y; Rabson AB. 2010. Immune activation induces immortalization of HTLV-1 LTR-Tax transgenic CD4+ T cells.. In: . . MGI: J:165866
Swain SD; Siemsen DW; Pullen RR; Han S. 2014. CD4+ T cells and IFN-gamma are required for the development of Pneumocystis-associated pulmonary hypertension.. In: . . MGI: J:206386
Szomolanyi-Tsuda E; Dundon PL; Joris I; Shultz LD; Woda BA; Welsh RM. 1994. Acute, lethal, natural killer cell-resistant myeloproliferative disease induced by polyomavirus in severe combined immunodeficient mice.. In: . . MGI: J:16875
Ta VB; de Haan AB; de Bruijn MJ; Dingjan GM; Hendriks RW. 2011. Pre-B-cell leukemias in Btk/Slp65-deficient mice arise independently of ongoing V(D)J recombination activity.. In: . . MGI: J:167638
Tadokoro Y; Ema H; Okano M; Li E; Nakauchi H. 2007. De novo DNA methyltransferase is essential for self-renewal, but not for differentiation, in hematopoietic stem cells.. In: . . MGI: J:125606
Takagi S; Saito Y; Hijikata A; Tanaka S; Watanabe T; Hasegawa T; Mochizuki S; Kunisawa J; Kiyono H; Koseki H; Ohara O; Saito T; Taniguchi S; Shultz LD; Ishikawa F. 2012. Membrane-bound human SCF/KL promotes in vivo human hematopoietic engraftment and myeloid differentiation.. In: . . MGI: J:180274
Takahama Y; Sugaya K; Tsuda S; Hasegawa T; Hashimoto Y. 1995. Regulation of early T cell development by the engagement of TCR-beta complex expressed on fetal thymocytes from TCR-beta-transgenic scid mice.. In: . . MGI: J:25533
Takahashi Y; Inamine A; Hashimoto S; Haraguchi S; Yoshioka E; Kojima N; Abe R; Takemori T. 2005. Novel role of the Ras cascade in memory B cell response.. In: . . MGI: J:100532
Takata M; Nakagomi T; Kashiwamura S; Nakano-Doi A; Saino O; Nakagomi N; Okamura H; Mimura O; Taguchi A; Matsuyama T. 2012. Glucocorticoid-induced TNF receptor-triggered T cells are key modulators for survival/death of neural stem/progenitor cells induced by ischemic stroke.. In: . . MGI: J:203071
Takenaka K; Prasolava TK; Wang JC; Mortin-Toth SM; Khalouei S; Gan OI; Dick JE; Danska JS. 2007. Polymorphism in Sirpa modulates engraftment of human hematopoietic stem cells.. In: . . MGI: J:127760
Takeuchi D; Jones VC; Kobayashi M; Suzuki F. 2008. Cooperative role of macrophages and neutrophils in host Antiprotozoan resistance in mice acutely infected with Cryptosporidium parvum.. In: . . MGI: J:139362
Tanaka S; Saito Y; Kunisawa J; Kurashima Y; Wake T; Suzuki N; Shultz LD; Kiyono H; Ishikawa F. 2012. Development of mature and functional human myeloid subsets in hematopoietic stem cell-engrafted NOD/SCID/IL2rgammaKO mice.. In: . . MGI: J:188959
Thayer TC; Delano M; Liu C; Chen J; Padgett LE; Tse HM; Annamali M; Piganelli JD; Moldawer LL; Mathews CE. 2011. Superoxide production by macrophages and T cells is critical for the induction of autoreactivity and type 1 diabetes.. In: . . MGI: J:186804
The Jackson Laboratory. 2005. Information obtained from The Jackson Laboratory, Bar Harbor, ME. In: . . MGI: J:101977
Thomas DC; Mellanby RJ; Phillips JM; Cooke A. 2007. An early age-related increase in the frequency of CD4+ Foxp3+ cells in BDC2.5NOD mice.. In: . . MGI: J:125536
Todorova D; Kim J; Hamzeinejad S; He J; Xu Y. 2016. Brief Report: Immune Microenvironment Determines the Immunogenicity of Induced Pluripotent Stem Cell Derivatives.. In: . . MGI: J:233079
Touvrey C; Couedel C; Soulas P; Couderc R; Jasin M; de Villartay JP; Marche PN; Jouvin-Marche E; Candeias SM. 2008. Distinct effects of DNA-PKcs and Artemis inactivation on signal joint formation in vivo.. In: . . MGI: J:137712
Tremblay AM; Missiaglia E; Galli GG; Hettmer S; Urcia R; Carrara M; Judson RN; Thway K; Nadal G; Selfe JL; Murray G; Calogero RA; De Bari C; Zammit PS; Delorenzi M; Wagers AJ; Shipley J; Wackerhage H; Camargo FD. 2014. The Hippo transducer YAP1 transforms activated satellite cells and is a potent effector of embryonal rhabdomyosarcoma formation.. In: . . MGI: J:214602
Trowbridge JJ; Scott MP; Bhatia M. 2006. Hedgehog modulates cell cycle regulators in stem cells to control hematopoietic regeneration.. In: . . MGI: J:113717
Tsai S; Serra P; Clemente-Casares X; Slattery RM; Santamaria P. 2013. Dendritic cell-dependent in vivo generation of autoregulatory T cells by antidiabetogenic MHC class II.. In: . . MGI: J:205347
Tsai S; Shameli A; Yamanouchi J; Clemente-Casares X; Wang J; Serra P; Yang Y; Medarova Z; Moore A; Santamaria P. 2010. Reversal of autoimmunity by boosting memory-like autoregulatory T cells.. In: . . MGI: J:179859
Tsuchiya T; Fukuda S; Hamada H; Nakamura A; Kohama Y; Ishikawa H; Tsujikawa K; Yamamoto H. 2003. Role of gamma delta T cells in the inflammatory response of experimental colitis mice.. In: . . MGI: J:106734
Tsuji H; Ishii-Ohba H; Noda Y; Kubo E; Furuse T; Tatsumi K. 2009. Rag-dependent and Rag-independent mechanisms of Notch1 rearrangement in thymic lymphomas of Atm(-/-) and scid mice.. In: . . MGI: J:144042
Tsuji Y; Watanabe T; Kudo M; Arai H; Strober W; Chiba T. 2012. Sensing of Commensal Organisms by the Intracellular Sensor NOD1 Mediates Experimental Pancreatitis.. In: . . MGI: J:187368
Tucker TA; Kundert JA; Bondareva AA; Schmidt EE. 2005. Reproductive and neurological Quakingviable phenotypes in a severe combined immune deficient mouse background.. In: . . MGI: J:98496
Turley SJ; Lee JW; Dutton-Swain N; Mathis D; Benoist C. 2005. Endocrine self and gut non-self intersect in the pancreatic lymph nodes.. In: . . MGI: J:104385
Ueno S; Lu J; He J; Li A; Zhang X; Ritz J; Silberstein LE; Chai L. 2014. Aberrant expression of SALL4 in acute B cell lymphoblastic leukemia: mechanism, function, and implication for a potential novel therapeutic target.. In: . . MGI: J:215705
Uhlig HH; McKenzie BS; Hue S; Thompson C; Joyce-Shaikh B; Stepankova R; Robinson N; Buonocore S; Tlaskalova-Hogenova H; Cua DJ; Powrie F. 2006. Differential activity of IL-12 and IL-23 in mucosal and systemic innate immune pathology.. In: . . MGI: J:113470
Unsinger J; McDonough JS; Shultz LD; Ferguson TA; Hotchkiss RS. 2009. Sepsis-induced human lymphocyte apoptosis and cytokine production in 'humanized' mice.. In: . . MGI: J:151270
Van Buul PP; De Rooij DG; Zandman IM; Grigorova M; Van Duyn-Goedhart A. 1995. X-ray-induced chromosomal aberrations and cell killing in somatic and germ cells of the scid mouse.. In: . . MGI: J:26914
VanBuskirk KM; O'Neill MT; De La Vega P; Maier AG; Krzych U; Williams J; Dowler MG; Sacci JB Jr; Kangwanrangsan N; Tsuboi T; Kneteman NM; Heppner DG Jr; Murdock BA; Mikolajczak SA; Aly AS; Cowman AF; Kappe SH. 2009. Preerythrocytic, live-attenuated Plasmodium falciparum vaccine candidates by design.. In: . . MGI: J:152010
Vanner RJ; Remke M; Gallo M; Selvadurai HJ; Coutinho F; Lee L; Kushida M; Head R; Morrissy S; Zhu X; Aviv T; Voisin V; Clarke ID; Li Y; Mungall AJ; Moore RA; Ma Y; Jones SJ; Marra MA; Malkin D; Northcott PA; Kool M; Pfister SM; Bader G; Hochedlinger K; Korshunov A; Taylor MD; Dirks PB. 2014. Quiescent sox2(+) cells drive hierarchical growth and relapse in sonic hedgehog subgroup medulloblastoma.. In: . . MGI: J:213713
Vemuri MC; Schiller E; Naegele JR. 2001. Elevated DNA double strand breaks and apoptosis in the CNS of scid mutant mice.. In: . . MGI: J:115402
Verma-Gandhu M; Bercik P; Motomura Y; Verdu EF; Khan WI; Blennerhassett PA; Wang L; El-Sharkawy RT; Collins SM. 2006. CD4+ T-cell modulation of visceral nociception in mice.. In: . . MGI: J:124915
Viatour P; Ehmer U; Saddic LA; Dorrell C; Andersen JB; Lin C; Zmoos AF; Mazur PK; Schaffer BE; Ostermeier A; Vogel H; Sylvester KG; Thorgeirsson SS; Grompe M; Sage J. 2011. Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway.. In: . . MGI: J:177573
Viret C; Leung-Theung-Long S; Serre L; Lamare C; Vignali DA; Malissen B; Carrier A; Guerder S. 2011. Thymus-specific serine protease controls autoreactive CD4 T cell development and autoimmune diabetes in mice.. In: . . MGI: J:173941
Viriyakosol S; Matthias MA; Swancutt MA; Kirkland TN; Vinetz JM. 2006. Toll-like receptor 4 protects against lethal Leptospira interrogans serovar icterohaemorrhagiae infection and contributes to in vivo control of leptospiral burden.. In: . . MGI: J:105019
Volkmann A; Doffinger R; Ruther U; Kyewski BA. 1996. Insertional mutagenesis affecting programmed cell death leads to thymic hyperplasia and altered thymopoiesis.. In: . . MGI: J:108193
Vujanovic L; Szymkowski DE; Alber S; Watkins SC; Vujanovic NL; Butterfield LH. 2010. Virally infected and matured human dendritic cells activate natural killer cells via cooperative activity of plasma membrane-bound TNF and IL-15.. In: . . MGI: J:162797
Waldner H; Sobel RA; Price N; Kuchroo VK. 2006. The autoimmune diabetes locus Idd9 regulates development of type 1 diabetes by affecting the homing of islet-specific T cells.. In: . . MGI: J:131655
Walzer PD; Runck J; Steele P; White M; Linke MJ; Sidman CL. 1997. Immunodeficient and immunosuppressed mice as models to test anti-Pneumocystis carinii drugs.. In: . . MGI: J:39028
Wang C; Bogue MA; Levitt JM; Roth DB. 1999. Irradiation-mediated rescue of T cell-specific V(D)J recombination and thymocyte differentiation in severe combined immunodeficient mice by bone marrow cells.. In: . . MGI: J:115093
Wang GY; So PL; Wang L; Libove E; Wang J; Epstein EH Jr. 2011. Establishment of murine basal cell carcinoma allografts: a potential model for preclinical drug testing and for molecular analysis.. In: . . MGI: J:182174
Wang J; Cho S; Ueno A; Cheng L; Xu BY; Desrosiers MD; Shi Y; Yang Y. 2008. Ligand-dependent induction of noninflammatory dendritic cells by anergic invariant NKT cells minimizes autoimmune inflammation.. In: . . MGI: J:140188
Wang LX; Kang G; Kumar P; Lu W; Li Y; Zhou Y; Li Q; Wood C. 2014. Humanized-BLT mouse model of Kaposi's sarcoma-associated herpesvirus infection.. In: . . MGI: J:206819
Wang P; Rodriguez RT; Wang J; Ghodasara A; Kim SK. 2011. Targeting SOX17 in human embryonic stem cells creates unique strategies for isolating and analyzing developing endoderm.. In: . . MGI: J:171124
Wang Y; Sul HS. 2009. Pref-1 regulates mesenchymal cell commitment and differentiation through Sox9.. In: . . MGI: J:147095
Warner T; Balish E. 1995. Pulmonary alveolar proteinosis. A spontaneous and inducible disease in immunodeficient germ-free mice.. In: . . MGI: J:24415
Wecker H; Grusby MJ; Auchincloss H Jr. 1995. Effector cells must recognize antigens expressed in the graft to cause efficient skin graft rejection in SCID mice.. In: . . MGI: J:25110
Wei J; Wunderlich M; Fox C; Alvarez S; Cigudosa JC; Wilhelm JS; Zheng Y; Cancelas JA; Gu Y; Jansen M; Dimartino JF; Mulloy JC. 2008. Microenvironment determines lineage fate in a human model of MLL-AF9 leukemia.. In: . . MGI: J:166360
Wei S; Kozono S; Kats L; Nechama M; Li W; Guarnerio J; Luo M; You MH; Yao Y; Kondo A; Hu H; Bozkurt G; Moerke NJ; Cao S; Reschke M; Chen CH; Rego EM; Lo-Coco F; Cantley LC; Lee TH; Wu H; Zhang Y; Pandolfi PP; Zhou XZ; Lu KP. 2015. Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer.. In: . . MGI: J:228245
Westwell-Roper C; Dai DL; Soukhatcheva G; Potter KJ; van Rooijen N; Ehses JA; Verchere CB. 2011. IL-1 blockade attenuates islet amyloid polypeptide-induced proinflammatory cytokine release and pancreatic islet graft dysfunction.. In: . . MGI: J:179268
White RE; Ramer PC; Naresh KN; Meixlsperger S; Pinaud L; Rooney C; Savoldo B; Coutinho R; Bodor C; Gribben J; Ibrahim HA; Bower M; Nourse JP; Gandhi MK; Middeldorp J; Cader FZ; Murray P; Munz C; Allday MJ. 2012. EBNA3B-deficient EBV promotes B cell lymphomagenesis in humanized mice and is found in human tumors.. In: . . MGI: J:184554
Wicklein D; Schmidt A; Labitzky V; Ullrich S; Valent P; Schumacher U. 2013. E- and p-selectins are essential for repopulation of chronic myelogenous and chronic eosinophilic leukemias in a scid mouse xenograft model.. In: . . MGI: J:204363
Wigginton JM; Lee JK; Wiltrout TA; Alvord WG; Hixon JA; Subleski J; Back TC; Wiltrout RH. 2002. Synergistic engagement of an ineffective endogenous anti-tumor immune response and induction of IFN-gamma and Fas-ligand-dependent tumor eradication by combined administration of IL-18 and IL-2.. In: . . MGI: J:109850
Wilkison M; Gauss K; Ran Y; Searles S; Taylor D; Meissner N. 2012. Type 1 interferons suppress accelerated osteoclastogenesis and prevent loss of bone mass during systemic inflammatory responses to pneumocystis lung infection.. In: . . MGI: J:185537
Willimann K; Matile H; Weiss NA; Imhof BA. 1995. In vivo sequestration of Plasmodium falciparum-infected human erythrocytes: a severe combined immunodeficiency mouse model for cerebral malaria.. In: . . MGI: J:28277
Winslow GM; Yager E; Shilo K; Collins DN; Chu FK. 1998. Infection of the laboratory mouse with the intracellular pathogen Ehrlichia chaffeensis.. In: . . MGI: J:48876
Wong FS; Du W; Thomas IJ; Wen L. 2005. The influence of the major histocompatibility complex on development of autoimmune diabetes in RIP-B7.1 mice.. In: . . MGI: J:109830
Woods NB; Bottero V; Schmidt M; von Kalle C; Verma IM. 2006. Gene therapy: therapeutic gene causing lymphoma.. In: . . MGI: J:108380
Wu T; Sun C; Chen Z; Zhen Y; Peng J; Qi Z; Yang X; Zhao Y. 2012. Smad3-deficient CD11b(+)Gr1(+) myeloid-derived suppressor cells prevent allograft rejection via the nitric oxide pathway.. In: . . MGI: J:190588
Wu X; Zhang W; Font-Burgada J; Palmer T; Hamil AS; Biswas SK; Poidinger M; Borcherding N; Xie Q; Ellies LG; Lytle NK; Wu LW; Fox RG; Yang J; Dowdy SF; Reya T; Karin M. 2014. Ubiquitin-conjugating enzyme Ubc13 controls breast cancer metastasis through a TAK1-p38 MAP kinase cascade.. In: . . MGI: J:216379
Wunderlich M; Chou FS; Link KA; Mizukawa B; Perry RL; Carroll M; Mulloy JC. 2010. AML xenograft efficiency is significantly improved in NOD/SCID-IL2RG mice constitutively expressing human SCF, GM-CSF and IL-3.. In: . . MGI: J:166359
Xie J; Broxmeyer HE; Feng D; Schweitzer KS; Yi R; Cook TG; Chitteti BR; Barwinska D; Traktuev DO; Van Demark MJ; Justice MJ; Ou X; Srour EF; Prockop DJ; Petrache I; March KL. 2015. Human adipose-derived stem cells ameliorate cigarette smoke-induced murine myelosuppression via secretion of TSG-6.. In: . . MGI: J:223580
Xu L; Mohammad KS; Wu H; Crean C; Poteat B; Cheng Y; Cardoso AA; Machal C; Hanenberg H; Abonour R; Kacena MA; Chirgwin J; Suvannasankha A; Srour EF. 2016. Cell Adhesion Molecule CD166 Drives Malignant Progression and Osteolytic Disease in Multiple Myeloma.. In: . . MGI: J:237854
Xu W; Xin L; Soong L; Zhang K. 2011. Sphingolipid degradation by Leishmania major is required for its resistance to acidic pH in the mammalian host.. In: . . MGI: J:175272
XuFeng R; Boyer MJ; Shen H; Li Y; Yu H; Gao Y; Yang Q; Wang Q; Cheng T. 2009. ADAR1 is required for hematopoietic progenitor cell survival via RNA editing.. In: . . MGI: J:153698
Yahata T; Ando K; Nakamura Y; Ueyama Y; Shimamura K; Tamaoki N; Kato S; Hotta T. 2002. Functional human T lymphocyte development from cord blood CD34+ cells in nonobese diabetic/Shi-scid, IL-2 receptor gamma null mice.. In: . . MGI: J:77239
Yamasaki H; Sada A; Iwata T; Niwa T; Tomizawa M; Xanthopoulos KG; Koike T; Shiojiri N. 2006. Suppression of C/EBP{alpha} expression in periportal hepatoblasts may stimulate biliary cell differentiation through increased Hnf6 and Hnf1b expression.. In: . . MGI: J:114400
Yamashita J; Iwamura C; Ito T; Narita M; Hara Y; Sasaki T; Masuda D; Takahashi M; Tsuchiya M; Hada K; Ishikawa M; Matsuo T; Ohno Y; Tanaka H; Maruyama H; Ogawa Y; Nakayama T. 2013. Paraoxonase-1 suppresses experimental colitis via the inhibition of IFN-gamma production from CD4 T cells.. In: . . MGI: J:204816
Yan BS; Pichugin AV; Jobe O; Helming L; Eruslanov EB; Gutierrez-Pabello JA; Rojas M; Shebzukhov YV; Kobzik L; Kramnik I. 2007. Progression of pulmonary tuberculosis and efficiency of bacillus Calmette-Guerin vaccination are genetically controlled via a common sst1-mediated mechanism of innate immunity.. In: . . MGI: J:154010
Yang C; Loehn M; Jurczyk A; Przewozniak N; Leehy L; Herrera PL; Shultz LD; Greiner DL; Harlan DM; Bortell R. 2015. Lixisenatide accelerates restoration of normoglycemia and improves human beta-cell function and survival in diabetic immunodeficient NOD-scid IL-2rg(null) RIP-DTR mice engrafted with human islets.. In: . . MGI: J:225120
Yang GX; Wu Y; Tsukamoto H; Leung PS; Lian ZX; Rainbow DB; Hunter KM; Morris GA; Lyons PA; Peterson LB; Wicker LS; Gershwin ME; Ridgway WM. 2011. CD8 T cells mediate direct biliary ductule damage in nonobese diabetic autoimmune biliary disease.. In: . . MGI: J:168755
Yang L; Chen G; Mohanty S; Scott G; Fazal F; Rahman A; Begum S; Hynes RO; Xu L. 2011. GPR56 Regulates VEGF Production and Angiogenesis during Melanoma Progression.. In: . . MGI: J:175446
Yang L; Friedland S; Corson N; Xu L. 2014. GPR56 inhibits melanoma growth by internalizing and degrading its ligand TG2.. In: . . MGI: J:208172
Yang PL; Althage A; Chung J; Maier H; Wieland S; Isogawa M; Chisari FV. 2010. Immune effectors required for hepatitis B virus clearance.. In: . . MGI: J:156523
Yang X; Zhang Y; Yang Y; Lim S; Cao Z; Rak J; Cao Y. 2013. Vascular endothelial growth factor-dependent spatiotemporal dual roles of placental growth factor in modulation of angiogenesis and tumor growth.. In: . . MGI: J:200676
Yang YG; Chen AM; Garrett LJ; Sergio JJ; Theodore P; Awwad M; VerHalen J; Bodine DM; Sachs DH; Sykes M. 2000. Development and analysis of transgenic mice expressing porcine hematopoietic cytokines: a model for achieving durable porcine hematopoietic chimerism across an extensive xenogeneic barrier.. In: . . MGI: J:94302
Yasuda A; Tsuji O; Shibata S; Nori S; Takano M; Kobayashi Y; Takahashi Y; Fujiyoshi K; Hara CM; Miyawaki A; Okano HJ; Toyama Y; Nakamura M; Okano H. 2011. Significance of remyelination by neural stem/progenitor cells transplanted into the injured spinal cord.. In: . . MGI: J:190194
Yasutomo K; Maeda K; Hisaeda H; Good RA; Kuroda Y; Himeno K. 1997. The Fas-deficient SCID mouse exhibits the development of T cells in the thymus.. In: . . MGI: J:40207
Yeh ES; Lew BO; Means AR. 2006. The loss of PIN1 deregulates cyclin E and sensitizes mouse embryo fibroblasts to genomic instability.. In: . . MGI: J:105781
Yi S; Ji M; Wu J; Ma X; Phillips P; Hawthorne WJ; O'Connell PJ. 2012. Adoptive transfer with in vitro expanded human regulatory T cells protects against porcine islet xenograft rejection via interleukin-10 in humanized mice.. In: . . MGI: J:196728
Yi Z; Diz R; Martin AJ; Morillon YM; Kline DE; Li L; Wang B; Tisch R. 2012. Long-term remission of diabetes in NOD mice is induced by nondepleting anti-CD4 and anti-CD8 antibodies.. In: . . MGI: J:208520
Yi Z; Li L; Garland A; He Q; Wang H; Katz JD; Tisch R; Wang B. 2012. IFN-gamma receptor deficiency prevents diabetes induction by diabetogenic CD4+, but not CD8+, T cells.. In: . . MGI: J:187880
Yoshida K; van den Berg TK; Dijkstra CD. 1994. The functional state of follicular dendritic cells in severe combined immunodeficient (SCID) mice: role of the lymphocytes.. In: . . MGI: J:16866
Yoshioka T; Otero J; Chen Y; Kim YM; Koutcher JA; Satagopan J; Reuter V; Carver B; de Stanchina E; Enomoto K; Greenberg NM; Scardino PT; Scher HI; Sawyers CL; Giancotti FG. 2013. beta4 Integrin signaling induces expansion of prostate tumor progenitors.. In: . . MGI: J:194482
Yoshizawa M; Okada T; Morikawa Y; Sasaki F; Kiso Y. 1994. Murine granulated metrial gland cell population in beige (bg/bg) and SCID (scid/scid) genotypes.. In: . . MGI: J:21177
Young D; Kearney JF. 1995. Sequence analysis and antigen binding characteristics of Ig SCID Ig+ mice.. In: . . MGI: J:25547
Yui MA; Rothenberg EV. 2004. Deranged early T cell development in immunodeficient strains of nonobese diabetic mice.. In: . . MGI: J:132809
Zane NA; Gundelach JH; Lindquist LD; Bram RJ. 2012. Essential role for CAML in follicular B cell survival and homeostasis.. In: . . MGI: J:183110
Zare F; Bokarewa M; Nenonen N; Bergstrom T; Alexopoulou L; Flavell RA; Tarkowski A. 2004. Arthritogenic properties of double-stranded (viral) RNA.. In: . . MGI: J:89689
Zavidij O; Ball CR; Herbst F; Fessler S; Schmidt M; von Kalle C; Glimm H. 2010. Hematopoietic activity of human short-term repopulating cells in mobilized peripheral blood cell transplants is restricted to the first 5 months after transplantation.. In: . . MGI: J:161539
Zhang B; Strauss AC; Chu S; Li M; Ho Y; Shiang KD; Snyder DS; Huettner CS; Shultz L; Holyoake T; Bhatia R. 2010. Effective targeting of quiescent chronic myelogenous leukemia stem cells by histone deacetylase inhibitors in combination with imatinib mesylate.. In: . . MGI: J:160523
Zhang C; Cui Y; Houston S; Chang LJ. 1996. Protective immunity to HIV-1 in SCID/beige mice reconstituted with peripheral blood lymphocytes of exposed but uninfected individuals.. In: . . MGI: J:37253
Zhang H; Hilton MJ; Anolik JH; Welle SL; Zhao C; Yao Z; Li X; Wang Z; Boyce BF; Xing L. 2014. NOTCH inhibits osteoblast formation in inflammatory arthritis via noncanonical NF-kappaB.. In: . . MGI: J:213803
Zhang H; Watanabe R; Berry GJ; Vaglio A; Liao YJ; Warrington KJ; Goronzy JJ; Weyand CM. 2017. Immunoinhibitory checkpoint deficiency in medium and large vessel vasculitis.. In: . . MGI: J:240876
Zhang H; Zhou X; McQuade T; Li J; Chan FK; Zhang J. 2011. Functional complementation between FADD and RIP1 in embryos and lymphocytes.. In: . . MGI: J:170816
Zhang JQ; Okumura C; McCarty T; Shin MS; Mukhopadhyay P; Hori M; Torrey TA; Naghashfar Z; Zhou JX; Lee CH; Roopenian DC; Morse HC 3rd; Davidson WF. 2004. Evidence for selective transformation of autoreactive immature plasma cells in mice deficient in Fasl.. In: . . MGI: J:94696
Zhang Q; Hossain DM; Duttagupta P; Moreira D; Zhao X; Won H; Buettner R; Nechaev S; Majka M; Zhang B; Cai Q; Swiderski P; Kuo YH; Forman S; Marcucci G; Kortylewski M. 2016. Serum-resistant CpG-STAT3 decoy for targeting survival and immune checkpoint signaling in acute myeloid leukemia.. In: . . MGI: J:232638
Zhang S; Yajima H; Huynh H; Zheng J; Callen E; Chen HT; Wong N; Bunting S; Lin YF; Li M; Lee KJ; Story M; Gapud E; Sleckman BP; Nussenzweig A; Zhang CC; Chen DJ; Chen BP. 2011. Congenital bone marrow failure in DNA-PKcs mutant mice associated with deficiencies in DNA repair.. In: . . MGI: J:171351
Zhang X; Wan G; Mlotshwa S; Vance V; Berger FG; Chen H; Lu X. 2010. Oncogenic Wip1 phosphatase is inhibited by miR-16 in the DNA damage signaling pathway.. In: . . MGI: J:164245
Zhang YW; Su Y; Lanning N; Gustafson M; Shinomiya N; Zhao P; Cao B; Tsarfaty G; Wang LM; Hay R; Vande Woude GF. 2005. Enhanced growth of human met-expressing xenografts in a new strain of immunocompromised mice transgenic for human hepatocyte growth factor/scatter factor.. In: . . MGI: J:239806
Zhao C; Marrero I; Narsale A; Moya R; Davies JD. 2015. CD4(+) CD44(v.low) cells are unique peripheral precursors that are distinct from recent thymic emigrants and stem cell-like memory cells.. In: . . MGI: J:229768
Zhao Y; Guo C; Hwang D; Lin B; Dingeldein M; Mihailescu D; Sam S; Sidhwani S; Zhang Y; Jain S; Skidgel RA; Prabhakar BS; Mazzone T; Holterman MJ. 2010. Selective destruction of mouse islet beta cells by human T lymphocytes in a newly-established humanized type 1 diabetic model.. In: . . MGI: J:164900
Zheng CF; Guan KL. 1993. Cloning and characterization of two distinct human extracellular signal-regulated kinase activator kinases, MEK1 and MEK2.. In: . . MGI: J:31929
Zheng M; Ramsay AJ; Robichaux MB; Norris KA; Kliment C; Crowe C; Rapaka RR; Steele C; McAllister F; Shellito JE; Marrero L; Schwarzenberger P; Zhong Q; Kolls JK. 2005. CD4+ T cell-independent DNA vaccination against opportunistic infections.. In: . . MGI: J:104584
Zhou P; Szot GL; Guo Z; Kim O; He G; Wang J; Grusby MJ; Newell KA; Thistlethwaite JR; Bluestone JA; Alegre ML. 2000. Role of STAT4 and STAT6 signaling in allograft rejection and CTLA4-Ig-mediated tolerance.. In: . . MGI: J:119580
Zhu C; Roth DB. 1995. Characterization of coding ends in thymocytes of scid mice: implications for the mechanism of V(D)J recombination.. In: . . MGI: J:28349
de Laval B; Pawlikowska P; Petit-Cocault L; Bilhou-Nabera C; Aubin-Houzelstein G; Souyri M; Pouzoulet F; Gaudry M; Porteu F. 2013. Thrombopoietin-increased DNA-PK-dependent DNA repair limits hematopoietic stem and progenitor cell mutagenesis in response to DNA damage.. In: . . MGI: J:194947
de Oliveira VL; Keijsers RR; van de Kerkhof PC; Seyger MM; Fasse E; Svensson L; Latta M; Norsgaard H; Labuda T; Hupkens P; van Erp PE; Joosten I; Koenen HJ. 2012. Humanized mouse model of skin inflammation is characterized by disturbed keratinocyte differentiation and influx of IL-17A producing T cells.. In: . . MGI: J:192181
van Buul PP; Abramsson-Zetterberg L; Zandman IM; van Duyn-Goedhart A. 1998. Further characterization of the radiosensitivity of the scid mouse.. In: . . MGI: J:115137
van Essen D; Dullforce P; Gray D. 2000. Role of B cells in maintaining helper T-cell memory.. In: . . MGI: J:106317
van Rossum AM; Lysenko ES; Weiser JN. 2005. Host and bacterial factors contributing to the clearance of colonization by Streptococcus pneumoniae in a murine model.. In: . . MGI: J:104292
van den Pol AN. 2009. Brain trauma enhances transient cytomegalovirus invasion of the brain only in mice that are immunodeficient.. In: . . MGI: J:153392
van der Touw W; Cravedi P; Kwan WH; Paz-Artal E; Merad M; Heeger PS. 2013. Cutting edge: Receptors for C3a and C5a modulate stability of alloantigen-reactive induced regulatory T cells.. In: . . MGI: J:204834
von Herrath MG; Dockter J; Oldstone MB. 1994. How virus induces a rapid or slow onset insulin-dependent diabetes mellitus in a transgenic model.. In: . . MGI: J:81287

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Also Known As: NOD scid gamma, NOD-scid IL2Rgnull, NOD-scid IL2Rgammanull, NSG

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Il2rgtm1Wjl

Allele Symbol: Il2rgtm1Wjl

Prkdcscid

Allele Symbol: Prkdcscid

Disease Terms

Research Areas By Genotype

This mouse can be used to support research in many areas including:

Genotype: Il2rgtm1Wjl related

Genotype: Prkdcscid related

Mammalian Phenotype Terms by Genotype

Genotype: Il2rgtm1Wjl/Il2rgtm1Wjl Prkdcscid/PrkdcscidNOD.Cg-Prkdcscid Il2rgtm1Wjl/Sz

mortality/aging

immune system phenotype

hematopoietic system phenotype

cellular phenotype

neoplasm

homeostasis/metabolism phenotype

endocrine/exocrine gland phenotype

Genotype: Il2rgtm1Wjl/Y Prkdcscid/PrkdcscidNOD.Cg-Prkdcscid Il2rgtm1Wjl/Sz

mortality/aging

cellular phenotype

hematopoietic system phenotype

immune system phenotype

endocrine/exocrine gland phenotype

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Additional - Il2rgtm1Wjl related

Additional - Prkdcscid related

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Also Known As: NOD scid gamma, NOD-scid IL2Rg^null, NOD-scid IL2Rgamma^null, NSG

Il2rg^tm1Wjl

Allele Symbol: Il2rg^tm1Wjl

Prkdc^scid

Allele Symbol: Prkdc^scid

Genotype: Il2rg^tm1Wjl related

Genotype: Prkdc^scid related

Genotype: Il2rg^tm1Wjl/Il2rg^tm1Wjl Prkdc^scid/Prkdc^scid
NOD.Cg-Prkdc^scid Il2rg^tm1Wjl/Sz

Genotype: Il2rg^tm1Wjl/Y Prkdc^scid/Prkdc^scid
NOD.Cg-Prkdc^scid Il2rg^tm1Wjl/Sz

Additional - Il2rg^tm1Wjl related

Additional - Prkdc^scid related