Neuroscience research is biologically complex, and translating discoveries into therapies carries significant translational risk. At JAX, we help academic and biopharma researchers reduce that risk with rigorously quality-controlled models and validated in vivo preclinical services. Our comprehensive catalog of well-characterized, disease-relevant mouse models and isogenic human iPSC lines supports reproducible, reliable, and biologically relevant studies. Researchers can use JAX® Mice directly in their labs, or seamlessly transition them into studies with our dedicated in vivo neuroscience team, which brings decades of experience designing and executing IND-supporting studies for multiple therapeutic modalities. With the models and expertise at JAX, your neuroscience research advances with confidence.
Leverage unmatched knowledge in breeding strategy, colony management, and disease phenotype onset across popular neurological models. We help you select the right model for your program to reduce variability and improve translational relevance.
Our In Vivo Preclinical Research Team combines deep knowledge of disease progression with extensively validated in vivo assays to deliver decision-making data. From global pharmaceutical companies to emerging biotechs and academic leaders, we support researchers in maximizing resources and minimizing risks.
Access a comprehensive catalog of human iPSC lines for Alzheimer’s disease and related dementias, ALS, Parkinson’s disease, frontotemporal dementia, and other neurodegenerative disorders. All lines undergo rigorous quality control ensuring reproducibility and experimental confidence.
Detect subtle phenotypic changes earlier and reduce study variability with our automated home-cage monitoring platform that enables 24/7 continuous, objective measurement of behavior and physiology.
JAX is committed to advancing the understanding of the nervous system with our extensive neuroscience portfolio. Researchers can access a diverse collection of genetically engineered mice and human iPSCs, as well as Envision™ - our AI-powered home cage monitoring platform, and comprehensive in vivo preclinical services at JAX.
