JAX® Mice are the most published and well-characterized mouse models in the world. We maintain the largest collection of human disease-relevant models for neurological and rare diseases. Our most popular models of Alzheimer's disease, ALS, Myotonic Dystrophy, and other conditions are available in the quantities you need to advance your program. Colonies are maintained at high health status using gold-standard colony management practices and rigorous genetic quality control. This ensures consistent health, and genetic quality and standardization across generations, so you can trust your results whether you order mice today or five or ten years from now.
We have unmatched expertise in the breeding and phenotype onset for the most popular models and can guide you in selecting the right strain for your specific program. All JAX Mice can be enrolled in breeding services to generate study-ready cohorts delivered directly to your lab or seamlessly transitioned into studies with our Preclinical In Vivo Services team.
JAX maintains a diverse panel of ALS models reflecting the major disease drivers, align your model with the specific pathogenic mechanism you’re studying, rather than relying on a one-size-fits-all system.
JAX has a range of well-characterized genetic systems (e.g., targeting FXN deficiency and GAA repeat expansions) that are maintained with strict genetic quality control, enabling reproducible studies of disease mechanisms and therapeutic interventions.
JAX provides a wide range of well-characterized muscular dystrophy mouse models with varying disease severity, all maintained under strict genetic quality control to ensure consistent and reproducible results.
Neurological preclinical research studies are often complex, resource intensive, and require extensive planning. During this webinar, we discuss best practices for model selection, study design, and experimental reproducibility. We also highlight specific examples from preclinical studies on Alzheimer's disease, Amyotrophic lateral sclerosis, and neurodevelopmental conditions.
