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Data & Resources

Mouse Phenome Database

Aging-related phenotypes of 32 inbred mouse strains.

Lifespan and Survival Curves

Characterizing inbred strains of mice for aging phenotypes.

IGF1

Center researchers measured plasma IGF1 levels in aging mice and revealed that IGF1 levels showed an inverse correlation with median lifespan at 6 months.

Heart Rate

Center researchers characterizing inbred strains of mice for aging phenotypes at 6,12, and 18 months of age have revealed a genetic influence on electrocardiogram (ECG) time intervals and heart rate in aging mice.

Collaborative Cross Resources

The following tissues are available from a Cross Sectional study of Collaborative Cross (CC) strains.

Protocols

Protocols are available to the Scientific Community opon request.

Diversity Outbred Resources

The following Tissues are from a cross sectional DO study.

Knockout (KO) Mouse

The Translational Core successfully implemented a standardized human-worm-mouse pipeline in which candidate genes identified via the CHARGE consortium are tested in C. elegans by shRNA knockdown for effects on lifespan. 

Leading the search for tomorrow's cures

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