APP Models
| MODEL | JAX # | TYPE | DESCRIPTION | REFERENCE | SOURCE |
|---|---|---|---|---|---|
| hAbeta | 33013 | Knock-in | humanized Abeta 1-42 | MODEL-AD | |
| floxed hAbeta | 31050 | Knock-in | humanized Abeta 1-42 with lox sites flanking exon 14 | PMID:33893290 | MODEL-AD |
| APP-GR | 38920 | Genome replacement | 350 kB human APP construct replacing mouse App | Koob | |
| APP SAA | 34711 | Knock-in | humanized Abeta 1-42 with Swedish, Arctic and Austrian mutations | PMID:35690868 | Denali Therapeutics |