Our all-inclusive, risk-free CRISPR/Cas9 mouse model generation service enables the generation of various mouse models including, knock-ins, knockouts, conditional knockouts, point mutations, and genetically humanized models.
If the mouse model you need doesn't exist, we can generate it for you. Leverage JAX expertise to generate the best model on the most appropriate background for your research, using proven techniques such as CRISPR/Cas9 gene editing, traditional DNA microinjection, and ES cell-based techniques to improve the translational relevance for your research.
Genome editing with CRISPR/Cas9 enables the generation of new mouse models with unprecedented speed and simplicity. The Jackson Laboratory was an early adopter of CRISPR/Cas9 technology for mouse model development, and in this brief guide we describe the technology and lessons learned to generate knockouts and knockins in more than a dozen different genetic backgrounds.
Protect your valuable strains from unfortunate events. JAX Cryopreservation Services offer fast and reliable recovery of archived embryos and sperm so you can feel assured about the safety of your strains.
Need dozens or hundreds of age-matched mice fast? Speed expansion via IVF rapidly develops mouse colonies at a specified and opportunistic pathogen-free status.
JAX can help you design the model you need and produce it on the genetic background of your choice by leveraging our 85+ years of mouse experience and our 8,500 mouse models. The guide explains how we can help every step of the way, from concept to providing phenotypic characterization, allowing you and your staff to focus on the research instead of breeding mice.
Our Breeding Services makes managing your mouse colonies easy and affordable. We'll make sure you get the mice you need when you need them.
Donating your strain to JAX fulfills NIH obligations to share mice with other scientists while significantly reducing the cost of maintaining your mouse models.