Lung cancer

Our PDX collection has over 50 unique lung cancer PDX models representing a diverse set of clinically relevant mutations currently observed in the clinic. All lung patient-derived lung cancer models are available for efficacy testing at JAX In Vivo Services. For many of our lung PDX tumors, gene expression data and genomic data, standard of care data and pathology images are available through the Mouse Tumor Biology Database.

Featured lung cancer PDX models

Model name Diagnosis Tumor markers Additional detail
TM00199

NSCLC: Adenocarcinoma

EGFR L858R

SOC data available

TM00206

NSCLC: Adenocarcinoma

ALK-ELM4 translocation

Variant data

TM00302

NSCLC: metastatic adenocarcinoma

 KRAS G12D; ALK+

SOC data available

TM00784

NSCLC: Adenocarcinoma

EGFR L858R

SOC data available

Additional lung cancer models are available in the Mouse Tumor Biology Database.


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