Spatial transcriptome analysis of young and old mice breast tissue to identify an association aging and transcriptome changes - Refinement of the Iso-seq and MAS-seq pipeline and development of RNA splicing consequence estimation approach- Exploring transcriptome changes in longitudinal samples to elucidate PARPi resistance mechanism in ovarian cancer patients- Large-scale isoform analysis to find cancer-specific isoform expression patterns (Long/short read RNA seq)