Single Cell Biology

The Single Cell Biology Laboratory (SCBL) is a multidisciplinary, research-driven and collaborative core service at The Jackson Laboratory

Specializing in technologies to study cell and tissue biology at single cell resolution. Located in Farmington CT and Bar Harbor ME, our services are available to JAX and UConn researchers through the JAX-UConn Shared Single Cell Genomics facility.


The SCBL strives to develop, validate, and make available state-of-the-art single cell and spatial technologies to the JAX and UConn research community. Our staff are highly experienced in single-cell isolation and tissue dissociation; cell capture, enrichment and isolation; molecular characterization; and the computational analysis of single-cell data sets. As many of these technologies are dissociative, we employ a number of complementary spatial and in situ assays to interrogate cellular biology in its native microenvironment. Moreover, to investigate the effects of perturbation on biological systems, we have established expertise in cellular model development—2D/3D cell lines, organoids, microtissues—and have developed a high-content cellular screening platform for high throughput imaging and biochemical characterization of models of interest.

Join Us

Interested in working with a world class team? Interested in cell biology, assay development, highly multiplexed imaging, and computational analysis? We are hiring!

  • Associate Research Scientist (PhD track)

  • Cellular Biologist I/II/III 

  • Research Data Analyst