Familial AD Models

MODEL	JAX #	DESCRIPTION	NOMENCLATURE	REFERENCE
APP^SAA	34711	Humanized Ab sequence with Swedish, Arctic and Austrian mutations	B6.Cg-App^tm1.1Dnli/J	PMID:35690868
APP^SDI	37453	Humanized Ab sequence with Swedish, Dutch and Iowa mutations	B6.Cg-App^{em7(hAbeta,SDI)Msasn}/Msasn
APP^SFL	37454	Humanized Ab sequence with Swedish, Florida and London mutations	B6.Cg-App^{em8(hAbeta,SFL)Msasn}/Msasn
APOE4/APP^SAA	39775	Humanized Ab sequence with Swedish, Arctic and Austrian mutations; humanized APOE4	B6.Cg-App^tm1.1DnliApoe^{tm1.1(APOE*4)Adiuj}/MSasnJ
hAbeta-Swe-loxp-KI	39630	Humanized Abeta 1-42 with the Swedish mutation and loxP sites flanking exon 16	B6.Cg-App^em1Aduci/J
hAbeta-Swe-Ibe-loxp-KI	39631	Humanized Abeta 1-42 with the Swedish and Iberian mutations and loxP sites flanking exon 16	B6.Cg-App^em2Aduci/J