CD34+ hu-NSG™ Mice

Hu-CD34+ NSG are NSG™ (NOD.Cg-Prkdcscid Il2rgtm1Wjl, Stock No. 005557) mice engrafted with human cord blood-derived CD34+ hematopoietic stem cells. CD34+ humanized-NSG mice exhibit stable, multi-lineage engraftment of functional human hematopoietic cells without GvHD. Hu-CD34+ NSG mice are the gold standard for reconstitution of the human immune system for immunology, immuno-oncology, and infectious disease research.

Body Weights for CD34+ hu-NSG™ Mice

CD34_body_weight

Weights of CD34+ hu-NSGTM mice were measured weekly beginning 4 weeks after engraftment.  All 40 mice on the study were confirmed to be engrafted with >25% hu-CD45+ peripheral blood cells at the standard time point for analysis (16 weeks after engraftment).  

 Weeks After Engraftment 6 7 8 9 10 11 12 13 14 15 16
 Mean Weight (grams) 16.6 16.9 18.3 19.3 20.4 20.7 20.8 21.7 21.3 22.1 22.1 22.0 22.5
 Standard Deviation 1.3  1.2 1.2 1.2 1.2 1.4 1.5 1.6 1.6 1.6 1.6 1.6 1.6