| MODEL | JAX # | TYPE | DESCRIPTION | SOURCE | NOMENCLATURE |
|---|
| MAPT(H1.0)-GR | 35398 | Gene replacement | 190kB human construct of H1 haplotype replacing mouse Mapt | Koob | B6J.B6N-Tc(HSA17)2Mdk/J |
| MAPT(H2.1)-GR | 33668 | Gene replacement | 190kB human construct of H2 haplotype replacing mouse Mapt | Koob | B6J.B6N(CBA)-Tc(HSA17)1Mdk/J |
| MAPT(H1.0*)P301L-GR | 37420 | Gene replacement | 190kB human construct of H1 haplotype with P301L variant replacing mouse Mapt | Koob | B6J.B6N-Tc(HSA17*P301L)1Mdk/J |
| MAPT(H1.0*N279K)-GR | 35794 | Gene replacement | 190kB human construct of H1 haplotype with N279K risk variant replacing mouse Mapt | Koob | B6J.B6N(Cg)-Tc(HSA17*N279K)1Mdk/J |
| MAPT 10IVS+16 C>T | 36664 | Gene replacement | 190kB human construct of H1 haplotype with non-coding C to T (rs63751011) mutation in intron 10 replacing mouse Mapt | Koob | B6(Cg)-Tc(HSA17*)1Mdk/J |
| MAPT(H1.0*)S320F-GR | 40796 | Gene replacement | 190kB human construct of H1 haplotype with S320F variant replacing mouse Mapt | MODEL-AD | B6J.Cg-Isr(HAS17;MAPT*S320F)1Adiuj/AdiujJ |
| MAPT(H1.0*)R406W-GR-GR | 40815 | Gene replacement | 190kB human construct of H1 haplotype with R406W variant replacing mouse Mapt | MODEL-AD | B6J.Cg-Isr(HAS17;MAPT*R406W)2Adiuj/AdiujJ |
| MAPT 10IVS+16 C>T | 36664 | Gene replacement | 190kB human construct of H1 haplotype with non-coding C to T (rs63751011) mutation in intron 10 replacing mouse Mapt | Koob | B6(Cg)-Isr(HSA17;rs63751011-T)3Mdk/J |
