Mouse Strain Datasheet - 030386
Mouse Strain Datasheet - 030386
C3(1)/TAg-REAR mice allow transplantation of TAg-expressing tumors and/or cell lines in the FVB/N genetic background, and are a novel immunocompetent transplant model for studying basal-like triple negative breast cancer, prostate tumors from TRAMP mice, C3(1)/TAg tumor cell lines, etc. In contrast to the higher-transgene copy C3(1)/TAg line (Stock No. 013591) from which it was derived, C3(1)/TAg-REAR mice have only one copy (or a partial copy) of the transgene - resulting in retained tolerance to SV40 TAg but no spontaneous cancer phenotype.
Jeffrey E Green, National Cancer Institute, National Institutes of Health (NIH/NCI)
Olga Aprelikova, National Cancer Institute, National Institutes of Health (NIH/NCI)
| Genetic Background | Generation |
|---|---|
|
?+pN2F2
|
| Allele Type |
|---|
| Transgenic (Inserted expressed sequence) |
Starting at:
| $255.00 Domestic price for female 4-week |
| 510.00 Domestic price for breeder pair |
| Service | Genotype | Price |
|---|---|---|
| Hemizygous or non-carrier for Tg(C3-1-TAg)cJeg |
We will fulfill your order by providing at least two carriers for each strain ordered. The total number, sex, and genotypes provided will vary, although typically 8 or more animals are provided. Please check genotypes which will be recovered. While the genotypes of all animals produced will be communicated to you prior to scheduling shipment, the genotypes of animals provided may not reflect the mating scheme and genotypes described in the strain description. Animals are typically ready to ship in 11-14 weeks. If a second recovery is required to produce the minimum number of animals, then delivery time would increase to approximately 25 weeks. If we fail to produce animals of the correct genotype, you will not be charged. We cannot guarantee the reproductive success of mice shipped to your facility. If the mice are lost after the first three days (post-arrival) or do not produce progeny at your facility, a new order and fee will be necessary.
Cryorecovery to establish a Dedicated Supply for greater quantities of mice. Mice recovered can be used to establish a dedicated colony to contractually supply you mice according to your requirements. Price by quotation.
| Frozen Mouse Embryo | $2,595.00 per straw or vial |
