This strain represents one of a panel of chromosome substitution (or consomic) strains. Each strain carries a chromosome from the C57BL/6ByJ strain introgressed into a 129P3/J background. These strains represent a tool for dissection of quantitative trait loci (QTL). In particular, these two strains exhibit differences in taste response, ingestive behavior, alcohol consumption, body size, and adiposity. Genome scans of crosses between these strains have detected QTLs for these phenotypes that cluster on Chr 1, 2, 7 and 9 (Adip2; Adip3, Adip5, Ap7q, Bwq5, Bwq6, Nattq1, Nattq2, Sucq).
In 2013, a 154 SNP (single nucleotide polymorphism) panel analysis covering all 19 chromosomes and the X chromosome was performed at The Jackson Laboratory. All markers on Chr 1 are fixed for the C57BL/6 allele type. The remaining markers are fixed for 129P3/J with the exception of 2 markers on Chr 18 that tested as heterozygous for C57BL/6 and 129P3/J.

This strain represents one of a panel of chromosome substitution (or consomic) strains. Each strain carries a chromosome from the C57BL/6ByJ strain introgressed into a 129P3/J background. These strains represent a tool for dissection of quantitative trait loci. In particular, these two strains exhibit differences in body composition, alcohol consumption and taste responsiveness.

This strain is hosted by NIH's MMRRC, which partners with JAX for the distribution of this and other strains. For additional information and to purchase, please visit the MMRRC site.