STOCK ey4/BOC

Stock number: 016848

Description

This strain is being bred to increase penetrance, is currently unavailable, and expected to be available in June 2022.

Mice homozygous for the eyeless 4 mutation display anophthalmia and lens-cornea synechia.

Detailed description

Mice homozygous for the eyeless 4 mutation display anophthalmia and lens-cornea synechia.

Development

The eyeless 4 mutation was identified in the C3Bir.129P2(B6)-Il10^tm1Cgn/Lt strain by the laboratory of Dr. Bo Chang at The Jackson Laboratory. The targeted mutation was removed from this line through backcrossing to C57BL/6J, but this line has not been backcrossed to the point of congenicity and has been bred to homozygosity for eyeless 4.

Allele

Symbol: ey4
Name: eyeless 4
MGI accession ID: MGI:5013381
Generation method: Spontaneous
Marker symbol: ey4
Marker name: eyeless 4
Chromosome: 2
Strain of origin: C3Bir.129P2(B6)-Il10^tm1Cgn/Lt
Molecular note: This spontaneous mutation was identified at The Jackson Laboratory.