STOCK ey4/BOC

Stock number: 016848

Description

Removal of this mouse colony is imminent. If live mice are needed for your studies, it is advised that they be ordered immediately. After removal, the mice will be available from a cryorecovery.

Mice homozygous for the eyeless 4 mutation display anophthalmia and lens-cornea synechia.

Detailed description

Mice homozygous for the eyeless 4 mutation display anophthalmia and lens-cornea synechia.

Development

The eyeless 4 mutation was identified in the C3Bir.129P2(B6)-Il10^tm1Cgn/Lt strain by the laboratory of Dr. Bo Chang at The Jackson Laboratory. The targeted mutation was removed from this line through backcrossing to C57BL/6J, but this line has not been backcrossed to the point of congenicity and has been bred to homozygosity for eyeless 4.

Allele

Symbol: ey4
Name: eyeless 4
MGI accession ID: MGI:5013381
Generation method: Spontaneous
Marker symbol: ey4
Marker name: eyeless 4
Chromosome: 2
Strain of origin: C3Bir.129P2(B6)-Il10^tm1Cgn/Lt
Molecular note: This spontaneous mutation was identified at The Jackson Laboratory.