| Allele Name | transgene insertion 37, Gordon Fishell |
| Allele Type | Transgenic (Recombinase-expressing, Inducible) |
| Allele Synonym(s) | Tg(Dlx1/2-cre/ERT2,-ALPP)37Fsh |
| Gene Symbol and Name | Tg(I12b-cre/ERT2,-ALPP)37Fsh, transgene insertion 37, Gordon Fishell |
| Gene Synonym(s) | |
| Promoter | Dlx1, distal-less homeobox 1, mouse, laboratory |
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| Expressed Gene | ESR1, estrogen receptor 1, human |
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| Expressed Gene | ALPP, alkaline phosphatase, placental, human |
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| Expressed Gene | cre, cre recombinase, bacteriophage P1 |
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| Site of Expression | Tamoxifen administration induces Cre recombination in the ventral telencephalon and diencephalon as early as embryonic day 10.5 and in the olfactory bulb interneurons as early as embryonic day 15.5. |
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| Strain of Origin | FVB/N |
| Chromosome | UN |
| Molecular Note | A targeting construct containing sequence encoding xre/ERT2 under the control of the mouse Dlx1/2, distal-less homeobox 1, distal-less homeobox 2, forebrain enhancer/ promoter, I12b, with an internal ribosomal entry sequence (IRES), followed by the human placental alkaline phosphatase gene (ALPP), and SV40 polyadenylation site sequence, was microinjected into FVB/N donor eggs. Founder line 37 was subsequently established. |
| Mutations Made By | Rob Machold, The Skirball Institute, NYU Sch. of Med. |
