These targeted mutant mice possess loxP sites on either side of the third coding exon of the <i>Pot1a</i> (protection of telomeres 1A) gene. Mice that are homozygous for this floxed allele are viable, fertile, normal in size and do not display any gross physical or behavioral abnormalities. When bred to mice that express Cre recombinase, resulting offspring will not express the targeted gene in cre-expressing tissues. 

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These targeted mutant mice possess loxP sites on either side of the third coding exon of the <i>Pot1a</i> gene. This floxed mouse line may be useful in studies of telomere biology.

Typically mice are recovered in 12-16 weeks. Contact Customer Service to place an order or for more information.

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