Mouse Strain Datasheet - 010726
Mouse Strain Datasheet - 010726
Homozygous M390R mutant Bbs1 (Bardet-Biedl syndrome 1 (human)) animals exhibit photoreceptor degeneration and severe obesity. Mice are hyperphagic and hyperleptinemic with reduced locomotor activity but no elevation of mean arterial blood pressure. Lateral ventricles in the brain are enlarged and the corpus striatum is reduced. Males lack sperm flagella and are infertile.
Val Sheffield, University of Iowa, HHMI
| Genetic Background | Generation |
|---|---|
|
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| Allele Type | Gene Symbol | Gene Name |
|---|---|---|
| Targeted | Bbs1 | Bardet-Biedl syndrome 1 (human) |
| Service | Genotype | Price |
|---|---|---|
| Heterozygous or wildtype for Bbs1<tm1Vcs> |
We will fulfill your order by providing at least two carriers for each strain ordered. The total number, sex, and genotypes provided will vary, although typically 8 or more animals are provided. Please check genotypes which will be recovered. While the genotypes of all animals produced will be communicated to you prior to scheduling shipment, the genotypes of animals provided may not reflect the mating scheme and genotypes described in the strain description. Animals are typically ready to ship in 11-14 weeks. If a second recovery is required to produce the minimum number of animals, then delivery time would increase to approximately 25 weeks. If we fail to produce animals of the correct genotype, you will not be charged. We cannot guarantee the reproductive success of mice shipped to your facility. If the mice are lost after the first three days (post-arrival) or do not produce progeny at your facility, a new order and fee will be necessary.
Cryorecovery to establish a Dedicated Supply for greater quantities of mice. Mice recovered can be used to establish a dedicated colony to contractually supply you mice according to your requirements. Price by quotation.
| Frozen Mouse Embryo | $2,595.00 per straw or vial |
