Homozygous mutants exhibit an abnormal gait and limb position of hind legs.
Read More +Genetic Background | Generation |
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Allele Type | Gene Symbol | Gene Name |
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Spontaneous | oar | oarleg |
Mice homozygous for the oarleg mutation display improper orientation of one or both hind limbs and when lifted by the tail they point their toes straight outward and hold the hind limbs stiffly in a manner that makes the appendage resemble an oar. An abnormal gait appears by approximately 2 weeks of age. Despite this, no obvious aberrations of the skeleton have been found and these mutants can orient and swim in water.
The oarleg mutation arose spontaneously on the BABL/cByJ background at The Jackson Laboratory in 2001 and has been maintained on this coisogenic inbred background by sibling breeding.
When using the oarleg mouse strain in a publication, please cite the originating article(s) and include JAX stock #010637 in your Materials and Methods section.
Facility Barrier Level Descriptions
Service/Product | Description | Price |
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Heterozygous for oar |
Frozen Mouse Embryo | BALB/cByJ-oar/GrsrJ | $2595.00 |
Frozen Mouse Embryo | BALB/cByJ-oar/GrsrJ | $2595.00 |
Frozen Mouse Embryo | BALB/cByJ-oar/GrsrJ | $3373.50 |
Frozen Mouse Embryo | BALB/cByJ-oar/GrsrJ | $3373.50 |
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The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project. We do not guarantee breeding performance and therefore suggest that investigators order more than one breeding pair to avoid delays in their research.
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