Mouse Strain Datasheet - 009045
Mouse Strain Datasheet - 009045
The 15 coding exons of the Apc (adenomatosis polyposis coli) gene are flanked by loxP sites. Germline heterozygous deletion of the floxed region results in a tumor-prone mouse similar to ApcMin animals. This mutant mouse strain is useful for studies of this tumor suppressor gene and serves as a mouse model of colon cancer.
Dr. Tyler Jacks, Massachusetts Institute of Technology
| Genetic Background | Generation |
|---|---|
|
?+pN2
|
| Allele Type | Gene Symbol | Gene Name |
|---|---|---|
| Targeted (Conditional ready (e.g. floxed), No functional change) | Apc | adenomatosis polyposis coli |
| Service | Genotype | Price |
|---|---|---|
| Please inquire |
We will fulfill your order by providing at least two carriers for each strain ordered. The total number, sex, and genotypes provided will vary, although typically 8 or more animals are provided. Please check genotypes which will be recovered. While the genotypes of all animals produced will be communicated to you prior to scheduling shipment, the genotypes of animals provided may not reflect the mating scheme and genotypes described in the strain description. Animals are typically ready to ship in 11-14 weeks. If a second recovery is required to produce the minimum number of animals, then delivery time would increase to approximately 25 weeks. If we fail to produce animals of the correct genotype, you will not be charged. We cannot guarantee the reproductive success of mice shipped to your facility. If the mice are lost after the first three days (post-arrival) or do not produce progeny at your facility, a new order and fee will be necessary.
Cryorecovery to establish a Dedicated Supply for greater quantities of mice. Mice recovered can be used to establish a dedicated colony to contractually supply you mice according to your requirements. Price by quotation.
| Frozen Mouse Embryo | $2,595.00 per straw or vial |
