behavior/neurological phenotype

• limb grasping
  • when picked up by the tail homozygotes pull their back legs in toward their bodies
  (MGI Ref ID J:140624)

• abnormal gait
  • wobbling gait recognized at 2 weeks of age
  (MGI Ref ID J:140624)

mammalian phenotype

• vision/eye phenotype
  • Normal - normal ophthalmoscopic examination at 1 month of age
  (MGI Ref ID J:140624)

• hearing/vestibular/ear phenotype
  • Normal - ABR is normal at one month of age
  (MGI Ref ID J:140624)

nervous system phenotype

• brain vacuoles
  • two mutant males at three weeks of age show vacuoles in the spinal cord white matter, peduncles, and eighth cranial nerve root
  (MGI Ref ID J:140624)

• abnormal spinal cord white matter morphology
  • two mutant males at three weeks of age show vacuoles in the spinal cord white matter, peduncles, and eighth cranial nerve root
  (MGI Ref ID J:140624)

• axonal dystrophy
  • at three weeks of age dystrophic axons are found in the spinal cord and brain stem
  (MGI Ref ID J:140624)