B6.Cg-oda/GrsrJ

Stock number: 008548
Product name: overall diluted appearance
Research areas: Dermatology Research

Description

Homozygous mutants are characterized by an overall lighter pigmentation.

Detailed description

Homozygotes can be identified by two weeks of age on this nonagouti background by their diluted steel grey coat color, which includes dilited pigment in the ears, feet, and tail. Homozygotes are viable and fertile.

Development

The overall diluted appearance mutation arose spontaneously in 2001 at The Jackson Laboratory in STOCK Tg(CAG-EGFP)D4Nagy/J (stock #003116), which has 129 sublines and ICR in its genetic background. This mutant subline was maintained by sibling intercrossing for several years before it was backcrossed onto the C57BL/6J background by backcross-intercross breeding. This strain reached generation N5 in 2011.

Allele

Symbol: oda
Name: overall diluted appearance
MGI accession ID: MGI:3851741
Generation method: Spontaneous
Marker symbol: oda
Marker name: overall diluted appearance
Chromosome: 14
Strain of origin: STOCK Tg(CAG-EGFP)D4Nagy/J
Molecular note: This heritable phenotypic marker arose spontaneously and the underlying mutant sequence has not been chaaracterized.