Homozygous mutants are characterized by an overall lighter pigmentation.
Read More +Genetic Background | Generation |
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|
Allele Type | Gene Symbol | Gene Name |
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Spontaneous | oda | overall diluted appearance |
Homozygotes can be identified by two weeks of age on this nonagouti background by their diluted steel grey coat color, which includes dilited pigment in the ears, feet, and tail. Homozygotes are viable and fertile.
The overall diluted appearance mutation arose spontaneously in 2001 at The Jackson Laboratory in STOCK Tg(CAG-EGFP)D4Nagy/J (stock #003116), which has 129 sublines and ICR in its genetic background. This mutant subline was maintained by sibling intercrossing for several years before it was backcrossed onto the C57BL/6J background by backcross-intercross breeding. This strain reached generation N5 in 2011.
Allele Name | overall diluted appearance |
---|---|
Allele Type | Spontaneous |
Allele Synonym(s) | |
Gene Symbol and Name | oda, overall diluted appearance |
Gene Synonym(s) | |
Strain of Origin | STOCK Tg(CAG-EGFP)D4Nagy/J |
Chromosome | 14 |
Molecular Note | This heritable phenotypic marker arose spontaneously and the underlying mutant sequence has not been chaaracterized. |
When using the overall diluted appearance mouse strain in a publication, please cite the originating article(s) and include JAX stock #008548 in your Materials and Methods section.
Facility Barrier Level Descriptions
Service/Product | Description | Price |
---|---|---|
Heterozygous for oda |
Frozen Mouse Embryo | B6.Cg-oda/GrsrJ Frozen Embryo | $2595.00 |
Frozen Mouse Embryo | B6.Cg-oda/GrsrJ Frozen Embryo | $2595.00 |
Frozen Mouse Embryo | B6.Cg-oda/GrsrJ Frozen Embryo | $3373.50 |
Frozen Mouse Embryo | B6.Cg-oda/GrsrJ Frozen Embryo | $3373.50 |
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The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project. We do not guarantee breeding performance and therefore suggest that investigators order more than one breeding pair to avoid delays in their research.
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