The transgene in these mice is composed of a human neurofilament light polypeptide (NEFL) promoter driving the expression of an enhanced yellow fluorescent protein-mouse neurofilament heavy chain (Nefh) fusion protein. Hemizygous mice exhibit fluorescence in axonal fibers, including those of sciatic nerves, optical nerves, and spinal cord.

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The transgene in these mice is composed of a human neurofilament light polypeptide (NEFL) promoter driving the expression of an enhanced yellow fluorescent protein-mouse neurofilament heavy chain (Nefh) fusion protein. Hemizygous mice exhibit fluorescence in axonal fibers, including those of sciatic nerves, optical nerves, and spinal cord.

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B6.Cg-Tg(NEFL-EYFP/Nefh)40Gsn/J Frozen Embryo