C;A-Bolt/GrsrJ

Stock number: 006448
Research areas: Developmental Biology Research

Description

This strain has been discontinued, please refer to Stock No. 011075

Detailed description

Mice carrying the dominant mutation lightning bolt tail have variable-length kinked tails, curved spine, and abnormal spinal vertebral bodies. When picked up by the tail, carriers orient their rear legs in abnormal positions. Only 25% of the offspring of heterozygote x heterozygote crosses express the lightning bolt tail phenotype suggesting prenatal lethality.

Development

The mutation lightning bolt tail arose spontaneously in a (BALB/cJ x A/J)F1 colony at The Jackson Laboratory in 1998, and has been maintained by sibling matings ever since. In 2006 this strain reached generation F26.

Allele

Symbol: Bolt
Name: lightning bolt tail
MGI accession ID: MGI:3689312
Generation method: Spontaneous
Marker symbol: Bolt
Marker name: lightning bolt tail
Chromosome: 11
Strain of origin: (BALB/cJ x A/J)F1