behavior/neurological phenotype

• impaired swimming
  • homozygotes swim tilted to one side in circles usually just below the surface of the water
  (MGI Ref ID J:156739)

• head tilt
  • severe
  (MGI Ref ID J:156739)

• circling
  (MGI Ref ID J:156739)

hearing/vestibular/ear phenotype

• increased or absent threshold for auditory brainstem response
  • at wean age homozygotes have severe hearing impairment as assessed by auditory-evoked brainstem response and are deaf by 70 days of age
  (MGI Ref ID J:156739)

• abnormal otolith morphology
  • whole mounts of inner ears show otoconial deficiencies that are likely due to displacement of the otolithic membrane
  (MGI Ref ID J:156739)

• deafness
  • profoundly deaf by 70 days of age
  (MGI Ref ID J:156739)