The spontaneous recessive rslk2J remutation in these mice affects coat color.
Read More +Genetic Background | Generation |
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|
Allele Type | Gene Symbol | Gene Name |
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Spontaneous | rslk | recessive spotting-like |
Mice homozygous for this spontaneous and recessive remutation are recognized by their diluted gray coat color and white spotting that occurs randomly on both dorsal and ventral sides of the mice. Homozygous mutants live a normal lifespan and both sexes breed.
The recessive spotting like 2 Jackson mutation (rslk2J) arose spontaneously on the C57BL/6J background at The Jackson Laboratory in 2004 when that strain was at generation F225. It has been maintained on C57BL/6J.
Allele Name | recessive spotting-like 2 Jackson |
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Allele Type | Spontaneous |
Allele Synonym(s) | |
Gene Symbol and Name | rslk, recessive spotting-like |
Gene Synonym(s) | |
Strain of Origin | C57BL/6J |
Chromosome | 5 |
Molecular Note | This spontaneous mutation was shown by a complementation test to be allelic to the original rslk allele. |
When using the recessive spotting-like 2 Jackson mouse strain in a publication, please cite the originating article(s) and include JAX stock #006107 in your Materials and Methods section.
Facility Barrier Level Descriptions
Service/Product | Description | Price |
---|---|---|
Heterozygous for rslk<2J> |
Frozen Mouse Embryo | C57BL/6J-rslk<2J>/GrsrJ | $2595.00 |
Frozen Mouse Embryo | C57BL/6J-rslk<2J>/GrsrJ | $2595.00 |
Frozen Mouse Embryo | C57BL/6J-rslk<2J>/GrsrJ | $3373.50 |
Frozen Mouse Embryo | C57BL/6J-rslk<2J>/GrsrJ | $3373.50 |
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The Jackson Laboratory has rigorous genetic quality control and mutant gene genotyping programs to ensure the genetic background of JAX® Mice strains as well as the genotypes of strains with identified molecular mutations. JAX® Mice strains are only made available to researchers after meeting our standards. However, the phenotype of each strain may not be fully characterized and/or captured in the strain data sheets. Therefore, we cannot guarantee a strain's phenotype will meet all expectations. To ensure that JAX® Mice will meet the needs of individual research projects or when requesting a strain that is new to your research, we suggest ordering and performing tests on a small number of mice to determine suitability for your particular project. We do not guarantee breeding performance and therefore suggest that investigators order more than one breeding pair to avoid delays in their research.
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