C57BL/6J-rslk^2J/GrsrJ

Stock number: 006107
Product name: recessive spotting-like 2 Jackson
Research areas: Dermatology Research

Description

The spontaneous recessive rslk^2J remutation in these mice affects coat color.

Detailed description

Mice homozygous for this spontaneous and recessive remutation are recognized by their diluted gray coat color and white spotting that occurs randomly on both dorsal and ventral sides of the mice. Homozygous mutants live a normal lifespan and both sexes breed.

Development

The recessive spotting like 2 Jackson mutation (rslk^2J) arose spontaneously on the C57BL/6J background at The Jackson Laboratory in 2004 when that strain was at generation F225. It has been maintained on C57BL/6J.

Allele

Symbol: rslk^2J
Name: recessive spotting-like 2 Jackson
MGI accession ID: MGI:3616701
Generation method: Spontaneous
Marker symbol: rslk
Marker name: recessive spotting-like
Chromosome: 5
Strain of origin: C57BL/6J
Molecular note: This spontaneous mutation was shown by a complementation test to be allelic to the original rslk allele.