Mice homozygous for the severe kyphosis mutation have open eyelids at birth leading to injury and blindness, a progressive S-shaped kyphosis of the lumbar region of the spine, and a resultant shortened trunk and higher tail position.  Small granulomas in muscle and brown fat are also found.  Death usually occurs between 3 and 6 months of age and homozygotes do not breed.

Homozygous mice carrying this spontaneous mutation exhibit a progressive S-shaped kyphosis of the lumbar region resulting in a shortened trunk.

Typically mice are recovered in 12-16 weeks. Contact Customer Service to place an order or for more information.

Typically mice are recovered in 12-16 weeks. <a target="_blank" href="https://www.jax.org/jax-mice-and-services/customer-support" rel="noreferrer">Contact Customer Service</a> to place an order or for more information.