Mice homozygous for the severe kyphosis mutation have open eyelids at birth leading to injury and blindness, a progressive S-shaped kyphosis of the lumbar region of the spine, and a resultant shortened trunk and higher tail position.  Small granulomas in muscle and brown fat are also found.  Death usually occurs between 3 and 6 months of age and homozygotes do not breed.

Homozygous mice carrying this spontaneous mutation exhibit a progressive S-shaped kyphosis of the lumbar region resulting in a shortened trunk.

Typically mice are recovered in 12-16 weeks. Contact Customer Service to place an order or for more information.

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