B6(129S4)-Hps6^ru-7J/GrsrJ

Stock number: 005559

Description

This strain is extinct. Please search JAX^® Mice Database for other alleles of Hps6.

Detailed description

Mice homozygous for the ruby-eye 7 Jackson mutation have ruby colored eyes and a grey coat on this predominantly C57BL/6J background.

Development

The ruby-eye 7 Jackson mutation arose spontaneously in the B6.129S4-Cd86^tm1Shr/J strain (stock #003609). This mutant subline was backcrossed once to C57BL/6J and selectively intercrossed to bred out the targeted mutation and this strain has been maintained subsequently by sibling mating.

Allele

Symbol: Hps6^ru-7J
Name: ruby-eye 7 Jackson
MGI accession ID: MGI:3770622
Generation method: Spontaneous
Marker symbol: Hps6
Marker name: HPS6, biogenesis of lysosomal organelles complex 2 subunit 3
Chromosome: 19
Strain of origin: B6.129S4-Cd86^tm1Shr/J
Molecular note: Mice carrying this new remutation were discovered in a colony at the Jackson Laboratory.
General note: This allele is extinct as of May 22, 2009.