Mice homozygous for the ruby-eye 7 Jackson mutation have ruby colored eyes and a grey coat on this predominantly C57BL/6J background.
The ruby-eye 7 Jackson mutation arose spontaneously in the B6.129S4-Cd86tm1Shr/J strain (stock #003609). This mutant subline was backcrossed once to C57BL/6J and selectively intercrossed to bred out the targeted mutation and this strain has been maintained subsequently by sibling mating.
|Allele Name||ruby-eye 7 Jackson|
|Gene Symbol and Name||Hps6, HPS6, biogenesis of lysosomal organelles complex 2 subunit 3|
|Strain of Origin||B6.129S4-Cd86tm1Shr/J|
|General Note||This allele is extinct as of May 22, 2009.|
|Molecular Note||Mice carrying this new remutation were discovered in a colony at the Jackson Laboratory.|