This strain is extinct, please refer to Stock No. 001594
Genetic Background | Generation |
---|---|
|
Allele Type | Gene Symbol | Gene Name |
---|---|---|
Spontaneous | Dtnbp1 | dystrobrevin binding protein 1 |
Allele Name | sandy |
---|---|
Allele Type | Spontaneous |
Allele Synonym(s) | Bloc1s8sdy; Dys KO; Dys-; sdy; sdy- |
Gene Symbol and Name | Dtnbp1, dystrobrevin binding protein 1 |
Gene Synonym(s) | |
Strain of Origin | DBA/2J |
Chromosome | 13 |
Molecular Note | The mutation in the sandy mouse has been attributed to a deletion in the Dtnbp1 gene from intron 5 nucleotide 3701 to intron 7 nucleotide 12377. The deletion results in the loss of 52 amino acids from position 119-172 and abolishes expression of the protein. Western analysis did not detect protein in hippocampus tissue from homozygous mutant mice. |
What information were you hoping to find through your search?
How easy was it to find what you were looking for?
We may wish to follow up with you. Enter your email if you are happy for us to connect and reachout to you with more questions.
Please Enter a Valid Email Address
Thank you for sharing your feedback! We are working on improving the JAX Mice search. Come back soon for exciting changes.